Observation of the reversibility of a covalent pyrrolobenzodiazepine (PBD) DNA adduct by HPLC/MS and CD spectroscopy

Pyrrolo[2,1-c][1,4]benzodiazepine as a Scaffold for the Design and Synthesis of Anti- Tumour Drugs

(2012) Laura Cipolla et al.   Anti-Cancer Agents in Medicinal Chemistry

Synthesis of DNA-Interactive Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs)

(2010) Dyeison Antonow et al.   CHEMICAL REVIEWS

Structure−Activity Relationships of Monomeric C2-Aryl Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Antitumor Agents

(2010) Dyeison Antonow et al.   JOURNAL OF MEDICINAL CHEMISTRY

DNA Sequence Preference and Adduct Orientation of Pyrrolo[2,1-c][1,4]benzodiazepine Antitumor Agents

(2010) Khondaker M. Rahman et al.   ACS Medicinal Chemistry Letters

Effect of microwave irradiation on covalent ligand–DNA interactions

(2009) Khondaker M. Rahman et al.   CHEMICAL COMMUNICATIONS

The Pyrrolobenzodiazepine Dimer SJG-136 Forms Sequence-Dependent Intrastrand DNA Cross-Links and Monoalkylated Adducts in Addition to Interstrand Cross-Links

(2009) Khondaker M. Rahman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Observation of a dynamic equilibrium between DNA hairpin and duplex forms of covalent adducts of a minor groove binding agent

(2008) Khondaker M. Rahman et al.   CHEMICAL COMMUNICATIONS

Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78

(2008) M. Kotecha et al.   MOLECULAR CANCER THERAPEUTICS

An assay combining high-performance liquid chromatography and mass spectrometry to measure DNA interstrand cross-linking efficiency in oligonucleotides of varying sequences

(2007) Mathangi Narayanaswamy et al.   ANALYTICAL BIOCHEMISTRY