Bridged nucleic acid conjugates at 6′-thiol: synthesis, hybridization properties and nuclease resistances

Antisense drug discovery and development

(2011) Tsuyoshi Yamamoto et al.   Future Medicinal Chemistry

The synthesis of double-headed nucleosides by the CuAAC reaction and their effect in secondary nucleic acid structures

(2011) Anna S. Jørgensen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Semisynthetic DNA-Protein Conjugates for Biosensing and Nanofabrication

(2010) Christof M. Niemeyer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Significantly Enhanced DNA Thermal Stability Resulting from Porphyrin H-Aggregate Formation in the Minor Groove of the Duplex

(2010) Adam W. I. Stephenson et al.   CHEMBIOCHEM

Pyrene-functionalized triazole-linked 2′-deoxyuridines—probes for discrimination of single nucleotide polymorphisms (SNPs)

(2010) Michael E. Østergaard et al.   CHEMICAL COMMUNICATIONS

A comparison of five bioconjugatable ferrocenes for labeling of biomolecules

(2010) Dongbiao Ge et al.   CHEMICAL COMMUNICATIONS

Synthesis, RNA selective hybridization and high nuclease resistance of an oligonucleotide containing novel bridged nucleic acid with cyclic urea structure

(2010) Masaru Nishida et al.   CHEMICAL COMMUNICATIONS

A novel bridged nucleoside bearing a conformationally switchable sugar moiety in response to redox changes

(2010) Takeshi Baba et al.   CHEMICAL COMMUNICATIONS

Recent developments in oligonucleotide conjugation

(2010) Yashveer Singh et al.   CHEMICAL SOCIETY REVIEWS

Locked Nucleic Acids: Promising Nucleic Acid Analogs for Therapeutic Applications

(2010) Rakesh N. Veedu et al.   CHEMISTRY & BIODIVERSITY

New Far-red and Near-infrared Fluorescent Probes with Large Stokes Shifts for Dual Covalent Labeling of DNA

(2010) Thomas Ehrenschwender et al.   Chemistry-An Asian Journal

Bridged Nucleic Acids: Development, Synthesis and Properties

(2010) Satoshi Obika et al.   HETEROCYCLES

Synthesis of 2′,4′-Propylene-Bridged (Carba-ENA) Thymidine and Its Analogues: The Engineering of Electrostatic and Steric Effects at the Bottom of the Minor Groove for Nuclease and Thermodynamic Stabilities and Elicitation of RNase H

(2010) Yi Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Amino acids attached to 2′-amino-LNA: synthesis and excellent duplex stability

(2010) Marie W. Johannsen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Non-viral siRNA delivery vectors: dendritic molecular transporter and molecular transporter nanovectors for target gene silencing

(2010) Sharon K. Hamilton et al.   Polymer Chemistry

Modification of nucleic acids using [3 + 2]-dipolar cycloaddition of azides and alkynes

(2010) A. V. Ustinov et al.   RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY

Multimodal Gadolinium-Enriched DNA-Gold Nanoparticle Conjugates for Cellular Imaging

(2009) Ying Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Solid-Phase Synthesis of Oligonucleotide Conjugates Useful for Delivery and Targeting of Potential Nucleic Acid Therapeutics

(2009) Harri Lönnberg   BIOCONJUGATE CHEMISTRY

Chemical Strategies for the Synthesis of Peptide−Oligonucleotide Conjugates

(2009) Kui Lu et al.   BIOCONJUGATE CHEMISTRY

Reduction-sensitive polymers and bioconjugates for biomedical applications

(2009) Fenghua Meng et al.   BIOMATERIALS

Synthesis of Several Types of Bridged Nucleic Acids

(2009) S. M. Abdur Rahman et al.   CHEMISTRY LETTERS

Cooperative DNA Probing Using a β-Cyclodextrin−DNA Conjugate and a Nucleobase-Specific Fluorescent Ligand

(2009) Toshihiro Ihara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biological Barriers to Therapy with Antisense and siRNA Oligonucleotides

(2009) R. Juliano et al.   MOLECULAR PHARMACEUTICS

Utilization of Intrachain 4′-C-Azidomethylthymidine for Preparation of Oligodeoxyribonucleotide Conjugates by Click Chemistry in Solution and on a Solid Support

(2008) Anu Kiviniemi et al.   BIOCONJUGATE CHEMISTRY

siRNA Conjugate Delivery Systems

(2008) Ji Hoon Jeong et al.   BIOCONJUGATE CHEMISTRY

Novel strategies for the site-specific covalent labelling of nucleic acids

(2008) Samuel H. Weisbrod et al.   CHEMICAL COMMUNICATIONS

Effect of the Nature of the Spacer on Gene Transfer Efficacies of Novel Thiocholesterol Derived Gemini Lipids in Different Cell Lines: A Structure–Activity Investigation

(2008) Avinash Bajaj et al.   JOURNAL OF MEDICINAL CHEMISTRY

Functionalized 2′-Amino-α-L-LNA: Directed Positioning of Intercalators for DNA Targeting

(2008) T. Santhosh Kumar et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

(2008) R. Juliano et al.   NUCLEIC ACIDS RESEARCH

Labeling of DNA via rearrangement of S-2-aminoethyl phosphorothioates to N-(2-mercaptoethyl)phosphoramidates

(2008) Menglin Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Carbon nanotube cell translocation and delivery of nucleic acidsin vitro and in vivo

(2007) Lara Lacerda et al.   JOURNAL OF MATERIALS CHEMISTRY