Glycosidase inhibition: assessing mimicry of the transition state

Altered Enthalpy−Entropy Compensation in Picomolar Transition State Analogues of Human Purine Nucleoside Phosphorylase

(2009) Achelle A. Edwards et al.   BIOCHEMISTRY

The crystal structure of a family GH25 lysozyme from Bacillus anthracis implies a neighboring-group catalytic mechanism with retention of anomeric configuration

(2009) Carlos Martinez-Fleites et al.   CARBOHYDRATE RESEARCH

Sugar-mimicking glycosidase inhibitors: bioactivity and application

(2009) N. Asano   CELLULAR AND MOLECULAR LIFE SCIENCES

A New Sialidase Mechanism

(2009) Thomas J. Morley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Streptococcus pneumoniaeEndohexosaminidase D, Structural and Mechanistic Insight into Substrate-assisted Catalysis in Family 85 Glycoside Hydrolases

(2009) D. Wade Abbott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring

(2009) Matilde Aguilar-Moncayo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Kinetic and Mechanistic Analysis ofTrypanosoma cruziTrans-Sialidase Reveals a Classical Ping-Pong Mechanism with Acid/Base Catalysis†

(2008) Iben Damager et al.   BIOCHEMISTRY

Teaching old enzymes new tricks: engineering and evolution of glycosidases and glycosyl transferases for improved glycoside synthesisThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Systems and Chemical Biology, and has undergone the Journal's usual peer review process.

(2008) Fathima Aidha Shaikh et al.   Biochemistry and Cell Biology

Molecular Basis for β-Glucosidase Inhibition by Ring-Modified Calystegine Analogues

(2008) Matilde Aguilar et al.   CHEMBIOCHEM

Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight into Evolution of Carbohydrate Metabolism by Human Gut Flora

(2008) Tracey M. Gloster et al.   CHEMISTRY & BIOLOGY

Mechanistic insights into glycosidase chemistry

(2008) David J Vocadlo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Covalent inhibitors of glycosidases and their applications in biochemistry and biology

(2008) B. P Rempel et al.   GLYCOBIOLOGY

Structural and Functional Analysis of a Glycoside Hydrolase Family 97 Enzyme fromBacteroides thetaiotaomicron

(2008) Momoyo Kitamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevation of GlobalO-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition ofO-GlcNAcase Does Not Induce Insulin Resistance

(2008) Matthew S. Macauley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and biochemical evidence for a boat-like transition state in β-mannosidases

(2008) Louise E Tailford et al.   Nature Chemical Biology

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

(2008) Scott A Yuzwa et al.   Nature Chemical Biology

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

(2008) B. L. Cantarel et al.   NUCLEIC ACIDS RESEARCH