Article
Optics
Pavan Chandra Konda, Jonathan M. Taylor, Andrew R. Harvey
Summary: The novel microscopy concept, Multi-Aperture Fourier ptychographic microscopy (MA-FPM), introduces parallel detectors in microscopy to increase the space-bandwidth-time product. By using a synthetic aperture technique and FP algorithms to recover phase, high-resolution, wide field-of-view images are synthesized.
OPTICS AND LASERS IN ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Xiaoli Wang, Yan Piao, Yuanshang Jin, Jie Li, Zechuan Lin, Jie Cui, Tingfa Xu
Summary: Fourier ptychographic microscopy is a new computational imaging technology that allows for a large field of view and high resolution. This article proposes a Fourier ptychographic reconstruction method applied to a self-training physical model, incorporating the SwinIR network for the first time. Experimental results demonstrate that the proposed method achieves the best evaluation index values and produces the highest quality image reconstruction after model training.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemical Research Methods
Ruofei Wu, Jiaxiong Luo, Jiancong Li, Hanbao Chen, Junrui Zhen, Sicong Zhu, Zicong Luo, Yanxiong Wu
Summary: This study proposes an aberration correction method (AA-P algorithm) based on an improved phase recovery strategy, which optimizes the spectral function and optical pupil function updates of the samples using adaptive modulation factors added during the iterations. Experimental results show that the proposed AA-P algorithm can recover complex amplitude images with clearer contours and higher phase contrast in optical systems with hybrid aberrations. The algorithm improves the image reconstruction quality by 82.6% compared to the existing EPRY-FPM algorithm.
JOURNAL OF BIOMEDICAL OPTICS
(2023)
Article
Optics
Lorenzo Valzania, Jonathan Dong, Sylvain Gigan
Summary: Ptychography is a promising phase retrieval technique that has seen advancements in spectral methods to accelerate gradient descent algorithms. Experimental data has shown three times faster ptychographic reconstructions with spectral initializations compared to standard gradient descent algorithms, with improved resilience to noise. There is potential for spectral methods to be implemented in large-scale iterative ptychographic algorithms without additional computational costs.
Article
Nanoscience & Nanotechnology
Kyung Chul Lee, Kyungwon Lee, Jaewoo Jung, Se Hee Lee, Donghyun Kim, Seung Ah Lee
Summary: The research introduces a high-performance microscope device that can be mounted on a smartphone, utilizing the smartphone's camera, display screen, and processor for imaging and image reconstruction. The device achieves high resolution and a wide field of view, with potential for a variety of clinical applications.
Article
Optics
Xiao Tao, Jinlei Zhang, Peng Sun, Chang Wang, Chenning Tao, Rengmao Wu, Zhenrong Zheng
Summary: The PSI-FPM system utilizes phase-coded speckle illumination and a phase-only SLM to greatly reduce the number of images needed for reconstruction and enhance the system's robustness. Validated through simulations and experiments, the system reconstructs high-resolution images and is suitable for various speckle imaging applications.
OPTICS COMMUNICATIONS
(2021)
Article
Engineering, Electrical & Electronic
Jiaxiong Luo, Ruofei Wu, Zicong Luo, Haishu Tan, Junrui Zhen, Sicong Zhu, Hanbao Chen, Jiancong Li, Yanxiong Wu
Summary: Fourier ptychographic microscopy is a computational imaging technique that combines a large field of view and high-resolution. This study developed a more general reconstruction algorithm based on the previous algorithm to improve the reliability and effectiveness of intensity correction.
IEEE PHOTONICS JOURNAL
(2022)
Article
Optics
Van Huan Pham, Byong Hyuk Chon, Hee Kyung Ahn
Summary: We propose a tunable reflective Fourier ptychographic microscopy approach that allows variable resolution and field of view using different objective lenses and a digital micromirror device. This approach applies several objective lenses without additional optical alignment to enhance resolution. We demonstrate the feasibility of this technique by using 10x and 50x objective lenses, and compare its resolution with conventional Fourier ptychographic microscopy to confirm the improved resolution.
OPTICAL ENGINEERING
(2023)
Article
Optics
D. Pirone, V. Bianco, M. Valentino, M. Mugnano, V. Pagliarulo, P. Memmolo, L. Miccio, P. Ferraro
Summary: This study successfully uses Fourier Ptychographic Microscopy (FPM) to investigate cell-substrate interaction on micropatterned substrates, solving the issue of layer decoupling. By computationally decoupling the images in FPM reconstruction, clear images of both layers can be extracted separately. This method allows for the restoration of quantitative phase-contrast maps of the cells and the separate extraction of cell morphology and the underlying wrinkled patterns. The results of this study pave the way for further research in mechanobiology and cells and tissue engineering.
OPTICS AND LASERS IN ENGINEERING
(2022)
Article
Optics
Shun Zhou, Jiaji Li, Jiasong Sun, Ning Zhou, Habib Ullah, Zhidong Bai, Qian Chen, Chao Zuo
Summary: Optical diffraction tomography (ODT) is a promising label-free three-dimensional microscopic method for measuring the refractive index distribution of optically transparent samples. Non-interferometric ODT techniques have gained attention, but suffer from low-frequency missing problems in high numerical aperture systems. Researchers have proposed transport-of-intensity Fourier ptychographic diffraction tomography (TI-FPDT) to address this issue. TI-FPDT combines ptychographic angular diversity with transport of intensity measurements to overcome reconstruction quality deterioration and refractive index underestimation in conventional FPDT.
Article
Engineering, Electrical & Electronic
Shuhe Zhang, Tos T. J. M. Berendschot, Jinhua Zhou
Summary: We propose a simple and efficient reconstruction algorithm, Elfpie, for Fourier ptychographic microscopy, which is robust to various system errors without the need for calibration or recovery. Elfpie utilizes a new image gradient-based data fidelity cost function regularized by global second-order total-variation regularization, and incorporates the AdaBelief optimizer with an adaptive learning rate.
Article
Cell Biology
Aiye Wang, Zhuoqun Zhang, Siqi Wang, An Pan, Caiwen Ma, Baoli Yao
Summary: This paper introduces a method called ADMM-FPM which utilizes the concept of alternating direction method of multipliers to solve the phase retrieval problem in Fourier ptychographic microscopy (FPM). Compared to existing algorithms, ADMM-FPM shows better stability and robustness under noisy conditions.
Article
Optics
An Pan, Aiye Wang, Junfu Zheng, Yuting Gao, Caiwen Ma, Baoli Yao
Summary: Fourier ptychographic microscopy (FPM) is a computational imaging technique that offers high resolution, wide field-of-view, and quantitative phase recovery. However, the presence of an imperceptible artifact caused by edge effect degrades the precision of phase imaging in FPM. To address this issue, two opposite algorithms called discrete cosine transform (DCT) and periodic plus smooth image decomposition (PPSID) were proposed and discussed systematically. The PPSID-FPM algorithm significantly improves the accuracy of phase measurement and is comparable to the conventional FPM algorithm.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Optics
Hongyang Zhao, Wangwei Hui, Qing Ye, Kaicheng Huang, Quishuai Shi, Jianguo Tian, Wenyuan Zhou
Summary: Fourier ptychographic microscopy (FPM) is a technique that overcomes the limitation of spatial bandwidth product to obtain images with both large field-of-view and high resolution. However, the sequential iterative calculation in the FPM reconstruction process reduces its efficiency. To address this, we propose a parallel FPM reconstruction method based on field programmable gate array (FPGA) to speed up the process. By computing multiple sub-regions in the Fourier domain in parallel, we achieve a speed nearly 180 times faster than traditional methods. The proposed method offers a new perspective on parallel computing for FPM reconstruction.
Article
Optics
Yefeng Shu, Jiasong Sun, Jiaming Lyu, Yao Fan, Ning Zhou, Ran Ye, Guoan Zheng, Qian Chen, Chao Zuo
Summary: Quantitative phase imaging (QPI) is a valuable tool in biomedical research for quantifying optical thickness variation in living cells and tissues. Fourier ptychographic microscopy (FPM) is a high-resolution QPI method that allows long-term label-free observation and quantitative analysis of large cell populations. However, achieving high spatial and temporal resolution over a long-time scale remains a challenge. This study presents an adaptive optical QPI method based on annular illumination FPM, which utilizes low-resolution images and real-time aberration correction to recover high-resolution phase images and achieve diffraction-limited performance across a wide field of view.
Review
Optics
Roarke Horstmeyer, Haowen Ruan, Changhuei Yang
Article
Physics, Multidisciplinary
Benjamin Judkewitz, Roarke Horstmeyer, Ivo M. Vellekoop, Ioannis N. Papadopoulos, Changhuei Yang
Article
Computer Science, Software Engineering
Jaewon Kim, Roarke Horstmeyer, Ig-Jae Kim, Ramesh Raskar
ACM TRANSACTIONS ON GRAPHICS
(2011)
Article
Biochemical Research Methods
Joseph L. Hollmann, Roarke Horstmeyer, Changhuei Yang, Charles A. DiMarzio
JOURNAL OF BIOMEDICAL OPTICS
(2013)
Article
Biochemical Research Methods
Joseph L. Hollmann, Roarke Horstmeyer, Changhuei Yang, Charles A. DiMarzio
JOURNAL OF BIOMEDICAL OPTICS
(2014)
Article
Optics
Benjamin Judkewitz, Ying Min Wang, Roarke Horstmeyer, Alexandre Mathy, Changhuei Yang
Article
Optics
Guoan Zheng, Roarke Horstmeyer, Changhuei Yang
Article
Optics
Roarke Horstmeyer, Se Baek Oh, Ramesh Raskar
Article
Optics
Roarke Horstmeyer, Richard Y. Chen, Benjamin Judkewitz, Changhuei Yang
Article
Optics
Guoan Zheng, Xiaoze Ou, Roarke Horstmeyer, Changhuei Yang
Article
Optics
Xiaoze Ou, Roarke Horstmeyer, Changhuei Yang, Guoan Zheng
Article
Multidisciplinary Sciences
Roarke Horstmeyer, Benjamin Judkewitz, Ivo M. Vellekoop, Sid Assawaworrarit, Changhuei Yang
SCIENTIFIC REPORTS
(2013)
Proceedings Paper
Microscopy
Joseph L. Hollmann, Roarke Horstmeyer, Changhuei Yang, Charles A. DiMarzio
THREE-DIMENSIONAL AND MULTIDIMENSIONAL MICROSCOPY: IMAGE ACQUISITION AND PROCESSING XXI
(2014)