Journal
OPTICS EXPRESS
Volume 21, Issue 20, Pages 24025-24038Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.21.024025
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Funding
- National Science Center proj.Maestro [DEC-2011/02/A/ST2/00302]
- EuroHORCs-European Science Foundation EURYI [EURYI-01/2008-PL]
- National Laboratory of Quantum Technology
- National Centre for Research and Development [PBS1/A9/20/2013]
- Polish Ministry of Science and Higher Education
- Nicolaus Copernicus University [398-F]
- European Social Fund
- Polish Government
- Foundation for Polish Science Team Programme [TEAM/2008-1/1]
- EU European Regional Development Fund
- European Research Council [279647]
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Although Doppler optical coherence tomography techniques have enabled the imaging of blood flow in mid-sized vessels in biological tissues, the generation of velocity maps of capillary networks remains a challenge. To better understand the origin and information content of the Doppler signal from small vessels and limitations of such measurements, we used joint spectral and time domain optical coherence tomography to monitor the flow in a model, semitransparent microchannel device. The results obtained for Intralipid, whole blood, as well as separated red blood cells indicate that the technique is suitable to record velocity profiles in vitro, in a range of microchannel configurations. (C)2013 Optical Society of America
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