Review
Medicine, General & Internal
Rui Xie, Bingjie Qiu, Jay Chhablani, Xinyuan Zhang
Summary: The advancement of optical coherence tomography (OCT) technology has greatly improved the analysis of choroidal morphology and physiology, especially with the use of enhanced depth imaging OCT and swept-source OCT. This has led to a better understanding of choroidal disorders in retinal and choroidal diseases.
FRONTIERS IN MEDICINE
(2021)
Article
Engineering, Multidisciplinary
Ganwei Yan, Kecheng Yang, Wei Li, Zhibiao Li, Xiaojun Yin, Min Xia
Summary: In this study, a spectral-domain optical coherence tomography (SD-OCT) system with a center wavelength of 1555 nm was tested for stability and accuracy in the micron to sub-micron range. The results showed that the system could provide accurate topographic height information and compared well with other commercial devices.
Article
Engineering, Manufacturing
Tristan G. Fleming, Samuel J. Clark, Xianqiang Fan, Kamel Fezzaa, Chu Lun Alex Leung, Peter D. Lee, James M. Fraser
Summary: In situ monitoring is crucial for laser powder bed fusion and laser welding in manufacturing complex metallic components. This study combines optical coherence tomography (OCT) and synchrotron X-ray imaging for real-time monitoring of keyhole profiles during laser material processing. The results reveal the causes of outliers in OCT depth measurements and demonstrate the ability to track bubble and pore formation events.
ADDITIVE MANUFACTURING
(2023)
Article
Optics
Sandro Heuke, Herve Rigneault, Anne Sentenac
Summary: Fourier Ptychography Tomography (FPT) is a novel computational technique for coherent imaging, capable of three-dimensional reconstructions of complex sample permittivity with increased resolution compared to standard microscopy. In the context of coherent anti-Stokes Raman scattering (CARS) imaging, FPT shows potential for enhanced resolution and optical sectioning, particularly with non-linear interactions.
Article
Physics, Applied
Jianfeng Wang, Eric J. Chaney, Edita Aksamitiene, Marina Marjanovic, Stephen A. Boppart
Summary: This report demonstrates the implementation of compressive sensing and sparse sampling in polarization sensitive optical coherence tomography to reduce the number of B-scans required for effective volumetric measurements. The results show that CS could reconstruct reasonably good PS-OCT measurements with a maximum reduced B-scan rate of 50%, thereby accelerating and doubling the rate of volumetric PS-OCT measurements.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2021)
Article
Optics
Yusi Miao, Jun Song, Myeong Jin Ju
Summary: A fast and practical computational cross-calibration method for multiple spectrometers is described, which constructs a signal correlation matrix and can be used for physical alignment or numerical matching of spectra. The performance is comparable to the previously reported optimization approach.
Article
Optics
Daewoon Seong, Won Ki, Pilun Kim, Jaeyul Lee, Sangyeob Han, Soojin Yi, Hong Kyun Kim, Mansik Jeon, Jeehyun Kim
Summary: This study developed a virtual intraoperative OCT angiography integrated surgical microscope, which can simultaneously visualize the morphological tissue structure and microvasculature data of the surgical region, demonstrating its potential application in in vivo imaging and simulated surgeries of small animals.
OPTICS AND LASERS IN ENGINEERING
(2022)
Article
Optics
Yusi Miao, Mahsa Siadati, Jun Song, Da Ma, Yifan Jian, Mirza Faisal Beg, Marinko Sarunic, Myeong Jin Ju
Summary: The article presents a coherent buffer averaging technique for megahertz-rate retinal imaging to improve OCTA contrast, demonstrating a 10-fold increase in phase alignment among buffers. This method provides better OCTA contrast than conventional approaches with a faster acquisition time.
Article
Optics
Tanbin Shao, Kecheng Yang, Min Xia, Wenping Guo
Summary: In this study, an enhanced dispersion-encoded full-range spectral interferometry technique is proposed and validated for improving measurement accuracy in samples with significant depth, inclination, and roughness. By removing the direct current and preserving data with good phase continuity, the accuracy of phase compensation is improved. The proposed technique extends the depth measurement range and achieves high axial measurement precision.
Article
Optics
Jianan Fang, Kun Huang, E. Wu, Ming Yan, Heping Zeng
Summary: This article introduces an infrared 3D imaging system capable of detecting three-dimensional structure and reflectivity information. The system operates at single-photon sensitivity and femtosecond timing resolution, enabling imaging under low-light conditions. By nonlinear frequency upconversion and recording with a silicon camera, the presented system achieves high lateral and depth resolutions for 3D reconstruction. Additionally, a numerical denoiser based on spatiotemporal correlation allows the retrieval of object profile and reflectivity even with a detected flux below 0.05 photons/pixel/second. This infrared 3D imager features high detection sensitivity, precise timing resolution, and wide-field operation, offering new possibilities in life and material sciences.
LIGHT-SCIENCE & APPLICATIONS
(2023)
Article
Optics
Xiangsen Guo, Guangyuan Ren, Jianbo Tang
Summary: In this study, an autocorrelation analysis-based optical coherence tomography (OCT) method was introduced for accurate measurement of blood flow velocity in the capillary network. The axial blood flow velocity was obtained from the phase change in the decorrelation period of the first-order field autocorrelation function (g1) of the OCT field data. The proposed method showed accurate measurement of axial speed in the range of 0.5-15 mm/s in phantom experiments, and it achieved robust axial velocity measurements with more than five times shorter acquisition time compared to phase-resolved Doppler optical coherence tomography (pr-DOCT) in living animals.
Article
Optics
Yahong Chen, Andreas Norrman, Sergey A. Ponomarenko, Ari T. Friberg
Summary: This study investigates the spin angular momentum (SAM) density associated with partially coherent surface-plasmon-polariton (SPP) vortex fields at a metal-air interface, revealing the influence of SPP electric-field and magnetic-field correlations on the SAM density distributions. The analysis demonstrates the essential role played by the coherence state of the partially coherent SPP vortex field in shaping the SAM density distributions.
Article
Engineering, Manufacturing
Sophia N. Economidou, Md Jasim Uddin, Manuel J. Marques, Dennis Douroumis, Wan Ting Sow, Huaqiong Li, Andrew Reid, James F. C. Windmill, Adrian Podoleanu
Summary: The 3DMNMEMS is a novel drug delivery device that combines 3D printing, microneedles, and Microelectromechanical Systems (MEMS) to achieve versatile and controllable transdermal drug delivery. By utilizing advanced imaging techniques, the device's ability to monitor the distribution of liquid in skin tissue in real time is demonstrated, with in vivo testing showing improved glycemic control compared to subcutaneous injections. These results highlight the potential of the 3DMNMEMS as a universal personalized care transdermal drug delivery system.
ADDITIVE MANUFACTURING
(2021)
Article
Engineering, Electrical & Electronic
George Giamougiannis, Apostolos Tsakyridis, Yangjin Ma, Angelina Totovic, Miltiadis Moralis-Pegios, David Lazovsky, Nikos Pleros
Summary: We proposed a novel interferometric coherent photonic crossbar architecture (Xbar) that can realize any tensor operator and achieve total loss-induced fidelity restoration. The Xbar layout significantly reduces the programming steps compared to traditional photonic schemes based on singular value decomposition (SVD). The theoretical analysis shows that the Xbar design has lower insertion losses and improved scalability potential compared to SVD-based schemes, making it suitable for alternative node technologies with lower energy consumption and higher operational speed.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Optics
Zunyue Zhang, Yi Wang, Jiarui Wang, Dan Yi, David Weng U. Chan, Wu Yuan, Hon Ki Tsang
Summary: In this study, a compact integrated scanning spectrometer is proposed, which utilizes a tunable micro-ring resonator and a single arrayed waveguide grating to achieve wide optical bandwidths and high spectral resolutions. The integrated spectrometer with germanium photodetectors demonstrates excellent performance.
PHOTONICS RESEARCH
(2022)
Article
Optics
Mojtaba Mohseni, Christoph Polzer, Thomas Hellerer
Article
Biochemical Research Methods
Fredrik Svedberg, Christian Brackmann, Thomas Hellerer, Annika Enejder
JOURNAL OF BIOMEDICAL OPTICS
(2010)
Article
Biochemical Research Methods
Christoph Polzer, Stefan Ness, Mojtaba Mohseni, Thomas Kellerer, Markus Hilleringmann, Joachim Raedler, Thomas Hellerer
BIOMEDICAL OPTICS EXPRESS
(2019)
Article
Optics
A. Zach, M. Mohseni, C. Polzer, J. W. Nicholson, T. Hellerer
Article
Biochemistry & Molecular Biology
Thomas Kellerer, Janko Janusch, Christian Freymueller, Adrian Ruehm, Ronald Sroka, Thomas Hellerer
Summary: This study utilized two different fluorescence lifetime measurement techniques to investigate the factors affecting fluorescence lifetime results, showing consistent results and revealing the strongest influencing factor on fluorescence lifetime. It also provides quantitative guidance on how to choose the most suitable technique and perform experiments correctly to obtain consistent fluorescence lifetime results.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Proceedings Paper
Engineering, Biomedical
Thomas Hellerer, Christoph Polzer, Axel Friedenauer, Isabel Greisberger, Bernhard Wolfring, Christoph Skrobol
MULTIPHOTON MICROSCOPY IN THE BIOMEDICAL SCIENCES XIX
(2019)
Proceedings Paper
Engineering, Electrical & Electronic
Marion Lang, Thomas Hellerer, Juergen Stuhler
PHOTONICS AND OPTOELECTRONICS MEETINGS (POEM) 2011: LASER AND TERAHERTZ SCIENCE AND TECHNOLOGY
(2012)
Article
Optics
Frank Lison, Thomas Hellerer
Article
Multidisciplinary Sciences
Thomas Hellerer, Claes Axaeng, Christian Brackmann, Per Hillertz, Marc Pilon, Annika Enejder
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2007)
Article
Physics, Multidisciplinary
A Kiraz, M Ehrl, T Hellerer, OE Müstecaplioglu, C Bräuchle, A Zumbusch
PHYSICAL REVIEW LETTERS
(2005)
Article
Physics, Applied
T Hellerer, AMK Enejder, A Zumbusch
APPLIED PHYSICS LETTERS
(2004)
Article
Chemistry, Physical
T Hellerer, A Schiller, G Jung, A Zumbusch
Article
Biophysics
P Zehetmayer, T Hellerer, A Parbel, H Scheer, A Zumbusch
BIOPHYSICAL JOURNAL
(2002)
Article
Physics, Atomic, Molecular & Chemical
M Clara, JE Braun, T Hellerer, HJ Neusser
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
(2000)
