Journal
OPTICS EXPRESS
Volume 17, Issue 4, Pages 2255-2263Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.17.002255
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Funding
- Natural Science and Engineering Research Council of Canada and Canadian Institute
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This work is related to the development of phase-sensitive methodologies in Surface Plasmon Resonance (SPR) biosensing. We take advantage of a specific angular dependence of phase of light, reflected under SPR geometry, on parameters of the SPR-supporting metal, and propose a polarimetry-based methodology to easily determine the optimal calibration zero point, corresponding to the maximal phase sensitivity. The proposed methodology can significantly facilitate the calibration of the system in field and multi-channel sensing, broaden the dynamic range, as well as contribute to the development of feedback loops. (C) 2009 Optical Society of America
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