Article
Chemistry, Analytical
Vignesh Ravichandran, Izabela Ciesielska-Wrobel, Md Abdullah al Rumonl, Dhaval Solanki, Kunal Mankodiya
Summary: This study focuses on the impedance characteristics of dry e-textile electrodes and a laser-cut knit electrode under various contact forces and moisture conditions. The results showed that certain electrodes exhibited a significant decrease in impedance after moisture exposure, indicating the impact of stitch design and moisture. However, after controlled drying, some electrodes experienced an increase in impedance. Overall, the knit electrode and embroidered electrodes demonstrated superior performance in terms of impedance, moisture retention, and ECG signal quality.
Article
Ophthalmology
Andrey Yurevich Andreev, Egor Olegovich Osidak, Timofei Evgenievich Grigoriev, Sergey Vladimirovich Krasheninnikov, Valeriy Dmitrievich Zaharov, Oleg Vadimovich Zaraitianc, Sergey Anatolievich Borzenok, Sergey Petrovich Domogatsky
Summary: This study aimed to investigate a new Viscoll collagen-based membrane for improving corneal biomechanical characteristics, with results showing that the membrane effectively increased corneal thickness and strengthened tissue while maintaining transparency in a rabbit model. The experiment demonstrated that the implanted corneas remained transparent, and there were significant improvements in strength and elasticity.
EXPERIMENTAL EYE RESEARCH
(2021)
Article
Chemistry, Physical
Wenbo Du, Zhengjun Yao, Oleksander Moliar, Xuewei Tao, Qichao Zhang, Petro Loboda, Changqing Shu, Shasha Zhang
Summary: The study found that as the freezing temperature decreases and the solid content increases, the porosity and wall thickness of the porous titanium scaffold increase, leading to improved mechanical properties. The relationship between structure and mechanical properties can be described by a specific formula.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Multidisciplinary Sciences
Chenglong Shi, Nana Lu, Yaru Qin, Mingdi Liu, Hongxia Li, Haichao Li
Summary: This study investigated bone scaffolds with elliptical pore structures similar to cancellous bone, finding that the size and angle distribution of elliptical pores can influence the mechanical properties and permeability of the scaffolds. Proper design can match the characteristics of human cancellous bone, showing great potential for research and application in the field of artificial bone scaffolds.
Article
Biotechnology & Applied Microbiology
Long Chao, Chen Jiao, Huixin Liang, Deqiao Xie, Lida Shen, Zhidong Liu
Summary: Human bone cells require highly demanded biomimetic design with porous structures attached to implants. The study found that the performance of porous structures can be controlled by the initial design of the microstructure and tissue morphology, allowing for accurate matching of natural bone performance. Research on the mechanical properties and permeability of porous structures can help address issues in existing biomimetic bone structures and promote cell adhesion, migration, and new bone attachment.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Polymer Science
Ziqi Wang, Junying Zhang, Hongqing Niu, Dezhen Wu, Mengying Zhang, Enlin Han, Jing Sheng, Xiaoguang Sun, Chao Fan
Summary: In this study, co-polyimide (PI) fibers with excellent mechanical and dielectric properties were prepared by the wet-spinning method. The relationship between the properties and microstructure of the heat-drawn co-PI fibers was investigated, showing that proper conditions led to fewer surface defects and homogeneous inner structure. This work highlights the structure-property relationship in annealed PI fibers, providing a new pathway to high-performance PI fibers.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Polymer Science
Yang Yu, Eunkyoung Shim
Summary: With the advancement of TPE technology, there is a growing interest in using these materials in the meltblowing process to enhance product performance; a new elastomeric meltblown fabric was successfully produced in this study, with research conducted on the relationship between structure, tensile properties, and meltblowing process parameters; reducing fiber diameter tends to increase the tensile strength of the fabric due to the creation of more fiber-to-fiber bond points.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Review
Chemistry, Multidisciplinary
Aileen M. Eagleton, Emma K. Ambrogi, Sophia A. Miller, Nataliia Vereshchuk, Katherine A. Mirica
Summary: Metal-organic frameworks (MOFs) integrated into textiles have the potential to contribute to the development of advanced wearable systems with multifunctional performance. This review highlights the multifunctionality and versatility of MOF-integrated textile systems, summarizing their applications in sensing, filtration, detoxification, drug delivery, UV protection, and photocatalysis.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Materials Science, Composites
Zhanyou Ji, Jianzhong Ma, Xiaojing Guo, Yingke Wu, Zhonglei Ma, Jianbin Qin, Liang Shao
Summary: By constructing a scaffold structure with controlled zinc oxide particles and epoxy resin, the dimensional stability of rubber foam was effectively improved, leading to enhanced mechanical properties and flame retardancy. The scaffold structure significantly reduced the shrinkage, increased rigidity, and maintained toughness of the foam, while also reinforcing its flame retardant properties.
COMPOSITES SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Biomedical
Janani Radhakrishnan, Manjula Muthuraj, Gnana Santi Phani Deepika Gandham, Swaminathan Sethuraman, Anuradha Subramanian
Summary: This study evaluates the potential of a composite scaffold made of nanohydroxyapatite, poly(hydroxybutyrate), and poly(epsilon-caprolactone) in promoting bone regeneration in a rabbit ulnar segmental defect model. The scaffold demonstrated excellent biocompatibility and supported osteoblast proliferation and mineralization in vitro. In vivo experiments showed directional bone tissue formation in the defect site using the scaffold, while the control group exhibited undesired sclerotic-like tissue formation. The developed composite scaffold exhibits osteoinductive and osteoconductive properties, making it a promising candidate for bone regenerative therapies.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2022)
Article
Polymer Science
Yong Liu, Yu Liu, Lei Shang, Yuhui Ao
Summary: The study systematically investigated the structural evolution of polyacrylonitrile fibers in stepwise heat treatment, revealing the key role of the temperature zone from 245 to 265 degrees Celsius in the formation of the skin-core structure. Tensile strength and modulus decreased during stabilization, reaching 4.273 GPa and 221.132 GPa, respectively after high-temperature carbonization. The elongation at break increased and then decreased, indicating a transition from toughness failure to brittleness failure.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Engineering, Manufacturing
Chinmai Bhat, Ajeet Kumar, Shang-Chih Lin, Jeng-Ywan Jeng
Summary: This study introduces a novel design and additive manufacturing method for technical textiles that can achieve tunable mechanical properties. By adjusting the relative placement of unit cells, chainmail fabrics with different flexibilities and mechanical properties can be obtained. Experimental and numerical evaluations show that FCC fabrics exhibit excellent load-bearing properties and energy absorption capacity. These tunable technical textiles have potential applications in lightweight and adaptive spinal posture-correcting braces, as well as in protective equipment.
ADDITIVE MANUFACTURING
(2023)
Article
Materials Science, Textiles
Ferid Kirci, Ecem Karamanlargil, Sena Cimilli Duru, Banu Nergis, Cevza Candan
Summary: Medical compression stockings are special products used for treating venous and vascular diseases, which can alleviate discomfort during long flights. Conventional compression stockings made of synthetic yarns have poor air and moisture permeability, while the new products developed in the study show improvements in comfort and pressure performance.
FIBERS AND POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
R. M. Abdel-Rahman, V. Vishakha, I. Kelnar, J. Jancar, A. M. Abdel-Mohsen
Summary: A 3D hybrid scaffold based on collagen-grafted-chitosan-glucan fiber was prepared, and the physicochemical and antibacterial properties of the scaffold were significantly improved by chemical modification.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Veronika Anohova, Lyudmila Asyakina, Olga Babich, Olga Dikaya, Aleksandr Goikhman, Ksenia Maksimova, Margarita Grechkina, Maxim Korobenkov, Diana Burkova, Aleksandr Barannikov, Anton Narikovich, Evgeny Chupakhin, Anatoly Snigirev, Sergey Antipov
Summary: The directed formation of living cell structures is crucial for tissue engineering. New 3D scaffold materials for living tissues are essential for the widespread use of regenerative medicine. This manuscript demonstrates the molecular structure study of Dosidicus gigas collagen and the potential for obtaining a thin membrane material. The collagen membrane exhibits high flexibility, plasticity, and mechanical strength.
Article
Sport Sciences
Tobias Siebert, Lars Donath, Mischa Borsdorf, Norman Stutzig
Summary: This study investigated the effects of static stretching, dynamic stretching, and myofascial foam rolling on hip flexion range of motion. The results showed significant increases in range of motion after static stretching and dynamic stretching, but not after foam rolling. Therefore, the increased range of motion observed with foam rolling may be due to a change in pain threshold.
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2022)
Article
Engineering, Biomedical
Nico Nitzsche, Tobias Siebert, Henry Schulz, Norman Stutzig
Summary: This study investigated the effect of additional plyometric training on the reactive jumping performance and lower leg muscle strength in rhythmic gymnasts. The results showed that the additional training significantly improved the jump height, reactive strength index, and performance in sport-specific tests.
ISOKINETICS AND EXERCISE SCIENCE
(2022)
Article
Physiology
Sven Weidner, Andre Tomalka, Christian Rode, Tobias Siebert
Summary: Eccentric muscle contractions play a vital role in our daily life, and the effect of stretch velocity on muscle force redevelopment has been investigated. The results suggest that the stretch velocity influences the occurrence of Give and force redevelopment. These findings have important implications for improving muscle models and predictions in multibody simulations.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Engineering, Biomedical
Fabian Kempter, Lorena Lantella, Norman Stutzig, Joerg Fehr, Tobias Siebert
Summary: Rotated head postures during low or moderate crash events can affect the static and dynamic behavior of muscle activity, potentially altering neck injury mechanisms.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)
Article
Cell Biology
Maria Kokozidou, Clemens Goegele, Felix Pirrung, Niels Hammer, Christian Werner, Benjamin Kohl, Judith Hahn, Annette Breier, Michaela Schroepfer, Michael Meyer, Gundula Schulze-Tanzil
Summary: This study characterizes the ligamentogenesis in embroidered poly(L-lactide-co-epsilon-caprolactone) (P(LA-CL)) / polylactic acid (PLA) constructs using a dynamic nude mice xenograft model. The scaffold did not affect mice weight development and organs, indicating no organ toxicity. Moreover, the scaffold maintained its size and shape and reflected a high cell viability prior to and following implantation. Scaffold functionalization with fluorinated collagen foam provides a promising approach for ACL tissue engineering.
HISTOCHEMISTRY AND CELL BIOLOGY
(2023)
Article
Engineering, Biomedical
Robin Trostorf, Enrique Morales Orcajo, Amelie Poetzke, Tobias Siebert, Markus Boel
Summary: This study investigated the three-dimensional deformations of the porcine urinary bladder and revealed the morphological changes, pressure, and stress characteristics of the bladder during passive and active phases. The findings are important for understanding the load transfer mechanisms within the urinary bladder and validating corresponding models.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Biophysics
Fabian Walter, Robert Seydewitz, Philipp Mitterbach, Tobias Siebert, Markus Boel
Summary: A three-dimensional model was developed to describe the passive mechanical behavior of anisotropic skeletal muscle tissue, and its validity was validated through experimental tests. The results showed that the mechanical behavior of the tissue varied depending on the fiber orientation and deformation mode, and the extensive dataset collected in this study can be used for different error measurements.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
(2023)
Article
Biology
Lisa Klemm, Robert Seydewitz, Tobias Siebert, Markus Boel
Summary: The contraction activation of smooth muscle in the stomach wall (SW) is coordinated by slow electrical waves initiated and propagated by interstitial cells of Cajal (ICC). This model integrates a biophysically based model of ICC pacemaker activity and a mechanical feedback mechanism to simulate gastric slow waves induced by abnormal stretching of the antral SW. The model predicts stretch-induced gastric arrhythmias, such as the emergence of an ectopic pacemaker in the gastric antrum.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Editorial Material
Biophysics
Christian Rode, Andre Tomalka, Reinhard Blickhan, Tobias Siebert
BIOPHYSICAL JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Clemens Goegele, Julia Vogt, Judith Hahn, Annette Breier, Ricardo Bernhardt, Michael Meyer, Michaela Schroepfer, Kerstin Schaefer-Eckart, Gundula Schulze-Tanzil
Summary: This study successfully established an enthesis-like construct by colonizing functionalized scaffolds with human mesenchymal stem cells (hMSCs) and rabbit ACL fibroblasts. The hMSCs adhered more rapidly than rabbit ACL fibroblasts and showed immunoreactivity of collagen type I in the bone zone.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Biomedical
Stefan Papenkort, Mischa Borsdorf, Markus Boel, Tobias Siebert
Summary: This study presents a realistic 3D geometry model of the porcine stomach based on photogrammetric reconstruction, which can be used for future investigations on stomach functioning. The study also provides data on the thickness distribution of the stomach wall's mucosa and tunica muscularis, as well as an algorithm for computing longitudinal and circumferential directions at local points.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Biotechnology & Applied Microbiology
Matthew Araz, Sven Weidner, Fabio Izzi, Alexander Badri-Sproewitz, Tobias Siebert, Daniel F. B. Haeufle
Summary: Neuromuscular control loops experience communication delays, but mammals can run robustly even in adverse conditions. Muscle preflexes, which act within milliseconds, may be crucial for this ability. Our study quantifies muscle work during the preflex phase and tests its force modulation, finding that muscles exhibit a stereotypical stiffness response and a velocity adaptation to the force related to the perturbation. These findings highlight the activity-dependent nature of muscle stiffness and damping characteristics, indicating that neural control can anticipate ground conditions and lead to neuromuscular adaptation.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Tobias Walter, Norman Stutzig, Tobias Siebert
Summary: This study investigates the effect of an active exoskeleton on back muscle activity when lifting weights. It was found that the use of the active exoskeleton significantly reduces muscle activity and perceived exertion. Therefore, active exoskeletons provide noticeable support when lifting heavy weights, reducing muscle activity and pressure on the lumbar region.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Clemens Goegele, Judith Hahn, Gundula Schulze-Tanzil
Summary: The firm integration of anterior cruciate ligament (ACL) grafts into bones remains a challenging issue in ACL reconstruction. To achieve a functional-tissue-engineered ACL substitute, robust bone attachment sites need to be re-established. This review discusses the peculiarities of synovioentheseal complexes at the femoral and tibial attachment sites and explores tissue engineering strategies to address them. Various material composites and manufacturing techniques have been applied to mimic the ACL enthesis tissue gradients, and functionalized materials and growth factors have been integrated for zone-dependent differentiation of precursor cells. However, the individual and asymmetric histoarchitectures of ACL entheses present a unique biomechanical microenvironment that must be considered in future ACL interface tissue engineering approaches.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Andre Tomalka, Maximilian Heim, Annika Klotz, Christian Rode, Tobias Siebert
Summary: This study investigates the functioning of mammalian skeletal muscle at short lengths and finds that sarcomeres can maintain regular thick filament arrangement and generate force even at extremely short lengths. Furthermore, the sarcomeres exhibit a bimodal length distribution and fibers remain shortened after deactivation, showing increased forces during passive re-elongation. These findings contradict the assumption of thick filament compression and support the model of thick filament sliding.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2022)
