Article
Ophthalmology
Zakariya A. Jarrar, Abdus Samad Ansari, Katie M. Williams, Dominic S. Wong, Pirro G. Hysi, Omar A. Mahroo, Christopher J. Hammond
Summary: The aim of this classical twin study is to determine the prevalence case wise concordance between monozygotic and dizygotic twin pairs, and heritability of common vitreomacular interface (VMI) abnormalities. The study found that VMI abnormalities have a genetic component and the prevalence increases with age. Further genetic studies are needed to identify genes and pathways related to these sight-threatening abnormalities.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Ophthalmology
Michael Grinton, Harry Melville, Grace George, Pallavi Tyagi, Peter Avery, Louisa Wickham, David H. Steel
Summary: The study found a significant correlation between FFW and VMT width in unilateral cases, as well as a strong correlation between VMT width, VRI, and outer retinal changes in bilateral cases. Individual variations in foveal morphology and presence of vitreoretinal interface changes are associated with the extent of VMT width, suggesting both genetic and acquired factors may determine their presence and extent.
ACTA OPHTHALMOLOGICA
(2021)
Article
Ophthalmology
Winfried M. Amoaku, Laura Cushley, Vittorio Silvestri, Stephen Akafo, Kwesi N. Amissah-Arthur, Seth Lartey, Courtney N. Hageman, Christian M. Pappas, William C. Hubbard, Paul S. Bernstein, Albert Vitale, Megan Roberts, Gianni Virgili, Gregory S. Hageman, Giuliana Silvestri
Summary: This study provides the first assessment of VMIA in Ghanaian Africans. VMIA is commonly observed in Africans, and there is no significant association between VMIA and AMD grade.
Article
Biology
Fabrizio Giansanti, Cristina Nicolosi, Daniela Bacherini, Federica Soloperto, Federica Sarati, Dario Giattini, Giulio Vicini
Summary: In this study, we compared the use of a heads-up 3D surgical viewing system with conventional microscope surgery in vitreoretinal surgery. The results showed no significant differences in surgical outcomes and duration between the two groups, suggesting that the 3D system is a valuable tool for treating different retinal diseases.
Article
Medicine, General & Internal
Hiroyuki Komatsu, Yoshihiko Usui, Kinya Tsubota, Risa Fujii, Takefumi Yamaguchi, Kazuichi Maruyama, Ryo Wakita, Masaki Asakage, Hiroyuki Shimizu, Naoyuki Yamakawa, Naoya Nezu, Koji Ueda, Hiroshi Goto
Summary: Comprehensive proteomic analysis revealed altered vitreous protein expression levels that can discriminate ocular sarcoidosis from other forms of uveitis. Neutrophil gelatinase-associated lipocalin (NGAL) and junctional adhesion molecules B (JAMB) were identified as potential biomarkers for ocular sarcoidosis, serving as an auxiliary tool for its diagnosis.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Katarzyna Nowomiejska, Mario Damiano Toro, Vincenza Bonfiglio, Aleksandra Czarnek-Chudzik, Agnieszka Brzozowska, Kamil Torres, Robert Rejdak
Summary: Retrospective study evaluating the use of a three-dimensional (3D) viewing system and a conventional microscope (CM) for pars plana vitrectomy (PPV) combined with cataract surgery in primary rhematogenous retinal detachment (RD) showed similar postoperative visual acuity and rate of complications.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Public, Environmental & Occupational Health
Sylvia Agyekum, Poemen P. Chan, Yuzhou Zhang, Zhaohua Huo, Benjamin H. K. Yip, Patrick Ip, Clement C. Tham, Li Jia Chen, Xiu Juan Zhang, Chi Pui Pang, Jason C. Yam
Summary: The rising global prevalence of myopia poses a significant public health concern. This systematic review examines the cost-effectiveness of interventions for treating myopia. Six studies meeting the eligibility criteria were included, assessing costs, quality-adjusted life years (QALYs), and incremental cost-effectiveness ratios (ICER). The findings suggest that photorefractive screening plus 0.01% atropine and corneal refractive surgery are cost-effective, while ranibizumab and conbercept show to be more cost-effective than photodynamic therapy for pathologic myopia. Prevention of myopia progression is more cost-effective than treating pathologic myopia.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Biology
Filippo Confalonieri, Vanessa Ferraro, Alessandra Di Maria, Alessandro Gaeta, Jose Luis Vallejo-Garcia, Paolo Vinciguerra, Xhevat Lumi, Goran Petrovski
Summary: A systematic review was conducted on the use of antiplatelets and/or anticoagulants in vitreoretinal surgery. The findings suggest that the benefits of using these medications seem to outweigh the disadvantages, which are mainly related to postoperative hemorrhagic complications.
Review
Biochemistry & Molecular Biology
Filippo Confalonieri, Hanna Haave, Ragnheidur Bragadottir, Ingar Stene-Johansen, Xhevat Lumi, Lyubomyr Lytvynchuk, Goran Petrovski
Summary: This article provides a systematic review on the use of intraoperative optical coherence tomography (iOCT) systems in the treatment of full-thickness macular holes (FTMHs). Despite the limited number of studies, the results suggest that iOCT may be a helpful tool for surgeons in planning and managing FTMH surgeries.
Article
Ophthalmology
David Ta Kim, David Chow
Summary: This study is the first to evaluate the effect of latency on 3D HUD for vitreoretinal surgery. The levels of latency in the current models of 3D HUD are unlikely to contribute to a decrease in surgical performance and usability with current technologies which have a latency of 70 ms.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Hien Thu Thi Nguyen, Tung Thanh Hoang, Chau Minh Pham, Thao Manh Nguyen, Trung M. Dang, Timothy R. Fricke
Summary: This study evaluated the prevalence and related factors of myopic retinopathy in Vietnam. The results showed that retinal disorders were common in Vietnamese people with high myopia, and degree of myopia and axial length were associated with increased risk of complications.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Biology
Barbara Parolini, Matteo Ripa, Rino Frisina, Veronika Matello, Lorenzo Motta
Summary: This study describes the advantages and feasibility of microscope-integrated intraoperative optical coherence tomography (i-OCT) in managing various vitreoretinal diseases in a real-life setting. The results showed that i-OCT was a useful diagnostic exam for all cases and significantly influenced surgical management.
Review
Ophthalmology
Maria Ana Martinez-Castellanos, Greacia Yael Ortiz-Ramirez
Summary: Despite advances in retinal surgical devices, removing thick membranes remains a challenge. Adapting tools for other purposes and achieving at least light perception in eyes considered untreatable is beneficial for circadian rhythm and brain development.
CURRENT OPINION IN OPHTHALMOLOGY
(2021)
Review
Medicine, General & Internal
Matteo Ripa, Georgios D. Panos, Robert Rejdak, Theodoros Empeslidis, Mario Damiano Toro, Ciro Costagliola, Andrea Ferrara, Stratos Gotzaridis, Rino Frisina, Lorenzo Motta
Summary: This study evaluated the morbidity frequency of sympathetic ophthalmia (SO) triggered by single or multiple vitreoretinal (VR) surgery procedures. The cumulative incidence of SO was found to be 0.14 in eyes without antecedent trauma or previous ocular surgery. For every 100 people who underwent VR surgery, the incidence of SO was 0.03. Thus, VR surgery should be considered as a possible inciting event for SO and when counseling patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Azine Datlibagi, Anna Zein-El-Din, Maxime Frohly, Francois Willermain, Christine Delporte, Elie Motulsky
Summary: Proliferative vitreoretinal diseases (PVDs), such as proliferative vitreoretinopathy (PVR), epiretinal membranes, and proliferative diabetic retinopathy, are characterized by the formation of proliferative membranes due to EMT of retinal pigment epithelium (RPE) and endothelial cells. In vitro models, including cell lines, stem-cell-derived RPE, and primary cells, are utilized to induce EMT and mimic PVD. In vivo PVR animal models are obtained through surgical means or intravitreal injection to investigate EMT and cell behavior. This review provides a comprehensive overview of the current models available for studying EMT in PVD.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Ophthalmology
Ignasi Jurgens, Amanda Rey
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2015)
Article
Ophthalmology
Amparo Navea Tejerina, Stela Vujosevic, Monica Varano, Catherine Egan, Sobha Sivaprasad, Geeta Menon, Pascale Massin, Frank D. Verbraak, Henrik Lund-Andersen, Jose P. Martinez, Ignasi Jurgens, Erica Smets, Caroline Coriat, Peter Wiedemann, Vitor Agoas, Giuseppe Querques, Frank G. Holz, Sandrina Nunes, Dalila Alves, Catarina Neves, Torcato Santos, Luisa Ribeiro, Francesco Bandello, Jose Cunha-Vaz
OPHTHALMIC RESEARCH
(2015)
Article
Ophthalmology
Francesco Bandello, Amparo Navea Tejerina, Stela Vujosevic, Monica Varano, Catherine Egan, Sobha Sivaprasad, Geeta Menon, Pascale Massin, Frank D. Verbraak, Henrik Lund-Andersen, Jose P. Martinez, Ignasi Juergens, R. M. Erica Smets, Caroline Coriat, Peter Wiedemann, Victor Agoas, Giuseppe Querques, Frank G. Holz, Sandrina Nunes, Dalila Alves, Catarina Neves, Torcato Santos, Luisa Ribeiro, Jose Cunha-Vaz
OPHTHALMIC RESEARCH
(2015)
Article
Ophthalmology
Stela Vujosevic, Monica Varano, Catherine Egan, Sobha Sivaprasad, Geeta Menon, Ali Erginay, Frank D. Verbraak, Henrik Lund-Andersen, Jose P. Martinez, Ignasi Juergens, Erica Smets, Caroline Coriat, Peter Wiedemann, Victor Agoas, Giuseppe Querques, Frank G. Holz, Sandrina Nunes, Dalila Alves, Catarina Neves, Torcato Santos, Luisa Ribeiro, Francesco Bandello, Amparo Navea Tejerina, Jose Cunha-Vaz
OPHTHALMIC RESEARCH
(2016)
Article
Ophthalmology
Amanda Rey, Ignasi Juergens, Agnieszka Dyrda, Xavier Maseras, Antonio Morilla
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2016)
Article
Ophthalmology
Amanda Rey, Lorena Castillo, Agnieszka Dyrda, Xavier Maseras, Ignasi Juergens
Article
Ophthalmology
Daniel Vila Sola, Cristofer Nienow, Ignasi Jurgens
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2017)
Article
Ophthalmology
Maria S. Pighin, Clara Berrozpe, Ignasi Jurgens
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2020)
Article
Ophthalmology
Raimondo Forte, Hanan Haulani, Ignasi Jurgens
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2020)
Article
Ophthalmology
Ignasi Jurgens, Roslyn Kathryn Manrique Lipa, Patricia Pera
OPHTHALMIC SURGERY LASERS & IMAGING RETINA
(2018)
Article
Ophthalmology
Raimondo Forte, Hanan Haulani, Agnieszka Dyrda, Ignasi Jurgens
Summary: In patients treated with hydroxychloroquine for more than 5 years, choroidal thinning and flow abnormalities in the retinal capillary plexuses and choriocapillaris may be observed on SS-OCTA, even if BCVA, FAF, mfERG, AVF, and SS-OCT results are normal.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Ahmad M. Mansour, Lorenzo Lopez-Guajardo, Silvana Belotto, Luiz H. Lima, Abdul Razzak Charbaji, Stephen G. Schwartz, Lihteh Wu, William E. Smiddy, Javier Ascaso, Ignasi Jurgens, Robert E. Foster, Ayman G. Elnahry, Suthasinee Sinawat, Isabel Pinilla, Eduardo Perez-Salvador Garcia, Marta Suarez Leoz, Nuria Olivier Pascual, Lucas Zago Ribeiro, Rosa Arroyo Castillo, Amparo Navea, Sibel Kadayifcilar, Abdallah A. Ellabban, Amanda Rey, Hana A. Mansour, Koushik Tripathy, Igor Kozak, Sami H. Uwaydat, Maria Sacramento Valero, Rosario Cobo-Soriano, Maria Dolores Diaz-Barreda, Laura Monje Fernandez, Fernando Gonzalez del Valle, Irene Lopez Liroz, Erika Vazquez Cruchaga, Alex Fonollosa, Olivia Esteban Floria, Maria Isabel Relimpio Lopez, Gaurav Shah, Maxwell J. Wingelaar, Raghav Ravani, Juan Donate-Lopez, Elena Rubio Velazquez, Maurizio Parodi
Summary: This study investigated the variables in patients with persistent subretinal fluid (SRF) after successful repair of retinal detachment. The results showed that the resolution time of SRF was positively correlated with the number of retinal breaks and increased myopia. The final BCVA was positively correlated with age, duration of retinal detachment, initial BCVA, and SRF resolution time. EZ restoration time was longer with more retinal tears, worse final BCVA, and the presence of macula-off retinal detachment.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Amanda Rey, Ignasi Juergens, Xavier Maseras, Agnieszka Dyrda, Patricia Pera, Antonio Morilla
CLINICAL OPHTHALMOLOGY
(2018)
Article
Ophthalmology
Luisa Ribeiro, Francesco Bandello, Amparo Navea Tejerina, Stela Vujosevic, Monica Varano, Catherine Egan, Sobha Sivaprasad, Geeta Menon, Pascale Massin, Frank D. Verbraak, Henrik Lund-Andersen, Jose P. Martinez, Ignasi Juergens, Erica Smets, Caroline Coriat, Peter Wiedemann, Victor Agoas, Giuseppe Querques, Frank G. Holz, Sandrina Nunes, Catarina Neves, Jose Cunha-Vaz
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2015)