Article
Radiology, Nuclear Medicine & Medical Imaging
Jie Chen, Chunchao Xia, Ting Duan, Likun Cao, Hanyu Jiang, Xijiao Liu, Zhen Zhang, Zheng Ye, Zhenru Wu, Ronghui Gao, Yujun Shi, Bin Song
Summary: Necrosis or severe ischemia was found to be a sensitive imaging feature of MTM-HCC, with a high specificity. The combination of specific findings allowed for noninvasive prediction of this subtype with good accuracy and excellent specificity.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyeon Ji Jang, Sang Hyun Choi, Se Jin Choi, Won-Mook Choi, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin
Summary: This study aimed to develop and evaluate a modified LI-RADS version 2018 for diagnosing hepatocellular carcinoma (HCC) < 1.0 cm. Significant ancillary features associated with HCC < 1.0 cm were determined and applied to the modified LI-RADS. The sensitivity of our modified LI-RADS using restricted diffusion was significantly higher than LI-RADS v2018, with similar specificity.
EUROPEAN RADIOLOGY
(2023)
Review
Chemistry, Analytical
Dongxu Zhao, Jian Cao, Lei Zhang, Shaohua Zhang, Song Wu
Summary: This article summarizes the importance of early diagnosis of hepatocellular carcinoma (HCC) and the limitations of current diagnostic methods. It introduces the applications of molecular imaging and MRI in HCC diagnosis, and discusses the prospects of developing molecular imaging probes.
Review
Oncology
Haneyeh Shahbazian, Mohammad Mirza-Aghazadeh-Attari, Ali Borhani, Alireza Mohseni, Seyedeh Panid Madani, Golnoosh Ansari, Timothy M. Pawlik, Ihab R. Kamel
Summary: Hepatocellular carcinoma and intrahepatic cholangiocarcinoma are the two most common primary malignant tumors of the liver. This review discusses and outlines the similarities and variations in imaging characteristics that can help distinguish between these two primary tumors. Understanding the available imaging techniques would assist in differentiating these primary malignancies.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shin Hye Hwang, Mi-Suk Park, Sumi Park, Joon Seok Lim, Seung Up Kim, Young Nyun Park
Summary: The study compared the performance of current guidelines for diagnosing hepatocellular carcinomas using gadoxetic acid-enhanced MRI. It found significant differences in sensitivity and specificity among the guidelines, especially for small nodules between 1 and 2 cm.
EUROPEAN RADIOLOGY
(2021)
Article
Immunology
Yidi Chen, Yun Qin, Yuanan Wu, Hong Wei, Yi Wei, Zhen Zhang, Ting Duan, Hanyu Jiang, Bin Song
Summary: An easy-to-use and noninvasive risk score combining preoperative EOB-MRI and clinical indicators has been developed to accurately predict positive GPC-3 expression in hepatocellular carcinoma (HCC).
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Qian Li, Tong Zhang, Feng Che, Shan Yao, Feifei Gao, Lisha Nie, Hehan Tang, Yi Wei, Bin Song
Summary: Intravoxel incoherent motion (IVIM) parameters, especially D and D* values, may serve as reliable preoperative predictors of liver regeneration.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Leyao Wang, Bing Feng, Dengfeng Li, Meng Liang, Shuang Wang, Sicong Wang, Xiaohong Ma, Xinming Zhao
Summary: This study aimed to evaluate the potential of preoperative MR imaging features and clinical parameters in risk stratification of patients with solitary HCC <= 5 cm without MVI after hepatectomy. The nomogram incorporating these risk factors showed good performance in predicting RFS and achieving risk stratification. Significant prognostic differences were found between high- and low-risk subgroups.
EUROPEAN RADIOLOGY
(2023)
Review
Medicine, General & Internal
Gianvito Candita, Sara Rossi, Karolina Cwiklinska, Salvatore Claudio Fanni, Dania Cioni, Riccardo Lencioni, Emanuele Neri
Summary: Hepatocellular carcinoma (HCC) is a significant cause of oncologic mortality worldwide and poses challenges for healthcare systems. Early detection and appropriate therapy are crucial for improving patient outcomes. Imaging techniques play a vital role in the surveillance, detection, diagnosis, and post-treatment follow-up of HCC. The unique imaging characteristics of HCC lesions, especially the assessment of their vascularity using contrast-enhanced CT, MR, or CEUS, allow for accurate noninvasive diagnosis and staging. The use of imaging has expanded to include the detection of early-stage hepatocarcinogenesis using ultrasound and hepatobiliary MRI contrast agents, as well as the application of artificial intelligence for diagnostic prediction, prognosis, and treatment evaluation.
Article
Gastroenterology & Hepatology
Yi-Di Chen, Ling Zhang, Zhi-Peng Zhou, Bin Lin, Zi-Jian Jiang, Cheng Tang, Yi-Wu Dang, Yu-Wei Xia, Bin Song, Li-Ling Long
Summary: A radiomics nomogram model based on radiomics scores and clinical features was developed using machine learning, which showed favorable predictive accuracy for evaluating microvascular invasion in small hepatocellular carcinoma.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Yun Zhang, Hong Wei, Bin Song
Summary: Hepatocellular carcinoma (HCC) is the majority of primary liver cancer and a major global health challenge. Thermal ablation, including radiofrequency ablation (RFA) and microwave ablation (MWA), is recommended for early-stage HCC. Magnetic resonance imaging (MRI) plays a central role in evaluating treatment response and patient prognosis.
INSIGHTS INTO IMAGING
(2023)
Review
Oncology
Yidi Chen, Chongtu Yang, Liuji Sheng, Hanyu Jiang, Bin Song
Summary: The immune microenvironment of hepatocellular carcinoma (HCC) plays a crucial role in tumor development and drug responses. Magnetic resonance imaging (MRI) has the potential to assess the immune microenvironment of HCC and predict tumor responses to immunotherapy. However, there are limitations that need to be addressed.
Article
Oncology
Feifei Gao, Yi Wei, Tong Zhang, Hanyu Jiang, Qian Li, Yuan Yuan, Shan Yao, Zheng Ye, Shang Wan, Xiaocheng Wei, Lisha Nie, Hehan Tang, Bin Song
Summary: Early detection and diagnosis of HCC is crucial for prognosis. This study evaluated the detection performance of hepatic nodules using different contrast agents and compared the diagnostic performances using different criteria. The results showed that different MR protocols provided high lesion detection rate and diagnostic performance for HCC.
FRONTIERS IN ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Hyo Jung Park, So Yeon Kim, Amit G. Singal, So Jung Lee, Hyung Jin Won, Jae Ho Byun, Sang Hyun Choi, Takeshi Yokoo, Min-Ju Kim, Young-Suk Lim
Summary: By comparing the performance of gadoxetic acid-enhanced abbreviated MRI (AMRI)-based surveillance and ultrasound-only surveillance in high-risk patients for hepatocellular carcinoma (HCC), it was found that AMRI-based surveillance had higher sensitivities and accuracies for early-stage HCC than ultrasound-only surveillance.
LIVER INTERNATIONAL
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ningbin Luo, Xiangyang Huang, Yinan Ji, Guanqiao Jin, Yunying Qin, Bangde Xiang, Danke Su, Weizhong Tang
Summary: This study found that the functional liver imaging score (FLIS) based on preoperative gadoxetic acid-enhanced MRI can predict posthepatectomy liver failure (PHLF) in hepatocellular carcinoma (HCC) patients. FLIS has a higher predictive power than the MELD score, ALBI score, and ICG-R15 clearance.
EUROPEAN RADIOLOGY
(2022)
