SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma

Bone Morphogenetic Proteins

(2014) A.C. Carreira et al.   JOURNAL OF DENTAL RESEARCH

Differential TIMP3 expression affects tumor progression and angiogenesis in melanomas through regulation of directionally persistent endothelial cell migration

(2013) Asha M. Das et al.   ANGIOGENESIS

Bone morphogenetic protein-9 induces epithelial to mesenchymal transition in hepatocellular carcinoma cells

(2013) Qi Li et al.   CANCER SCIENCE

Identification of molecular alterations in gastrointestinal carcinomas and dysplastic hamartomas in Peutz-Jeghers syndrome

(2013) Susanne E. Korsse et al.   CARCINOGENESIS

Tumor promotion through the mesenchymal stem cell compartment in human hepatocellular carcinoma

(2013) Pratika Y. Hernanda et al.   CARCINOGENESIS

Smad phospho-isoforms direct context-dependent TGF-β signaling

(2013) Koichi Matsuzaki   CYTOKINE & GROWTH FACTOR REVIEWS

Loss of SMAD4 From Colorectal Cancer Cells Promotes CCL15 Expression to Recruit CCR1+ Myeloid Cells and Facilitate Liver Metastasis

(2013) Yoshiro Itatani et al.   GASTROENTEROLOGY

A Restricted Spectrum of Mutations in the SMAD4 Tumor-Suppressor Gene Underlies Myhre Syndrome

(2012) Viviana Caputo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Smad4 Expression in Hepatocellular Carcinoma Differs by Hepatitis Status

(2012) Lei Yao et al.   Asian Pacific Journal of Cancer Prevention

BMP4 Administration Induces Differentiation of CD133+Hepatic Cancer Stem Cells, Blocking Their Contributions to Hepatocellular Carcinoma

(2012) Lixing Zhang et al.   CANCER RESEARCH

Augmented autocrine bone morphogenic protein (BMP) 7 signaling increases the metastatic potential of mouse breast cancer cells

(2012) Hirofumi Sakai et al.   CLINICAL & EXPERIMENTAL METASTASIS

Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer

(2012) Alexander Pedroza-Gonzalez et al.   HEPATOLOGY

BMP-2 inhibits tumor growth of human renal cell carcinoma and induces bone formation

(2012) Lin Wang et al.   INTERNATIONAL JOURNAL OF CANCER

The Activation of MEK/ERK Signaling Pathway by Bone Morphogenetic Protein 4 to Increase Hepatocellular Carcinoma Cell Proliferation and Migration

(2012) C.-Y. Chiu et al.   MOLECULAR CANCER RESEARCH

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BMP activated Smad signaling strongly promotes migration and invasion of hepatocellular carcinoma cells

(2011) Ulrike Maegdefrau et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Bone morphogenetic protein −4 and −5 in pancreatic cancer—Novel bidirectional players

(2011) Siru Virtanen et al.   EXPERIMENTAL CELL RESEARCH

Disturbance of the microRNA pathway by commonly used lentiviral shRNA libraries limits the application for screening host factors involved in hepatitis C virus infection

(2011) Qiuwei Pan et al.   FEBS LETTERS

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

(2011) Zhihu Ding et al.   NATURE

Bone Morphogenetic Proteins and Cancer

(2010) Jayesh P. Thawani et al.   NEUROSURGERY

Strong Smad4 Expression Correlates with Poor Prognosis After Surgery in Patients with Hepatocellular Carcinoma

(2009) Kiyokazu Hiwatashi et al.   ANNALS OF SURGICAL ONCOLOGY

Smad2 and Smad3 Phosphorylated at Both Linker and COOH-Terminal Regions Transmit Malignant TGF-β Signal in Later Stages of Human Colorectal Cancer

(2009) Koichi Matsuzaki et al.   CANCER RESEARCH

Antimetastatic Role of Smad4 Signaling in Colorectal Cancer

(2009) Bixiang Zhang et al.   GASTROENTEROLOGY

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-β signaling from tumor suppression to oncogenesis in early chronic hepatitis B

(2009) Miki Murata et al.   HEPATOLOGY

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

Synergistic antitumor activity of XIAP-shRNA and TRAIL expressed by oncolytic adenoviruses in experimental HCC

(2007) Qiuwei Pan et al.   ACTA ONCOLOGICA

The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer

(2007) Liudmila L. Kodach et al.   CANCER