Functional antagonism between pro-apoptotic BIM and anti-apoptotic BCL-XL in MYC-induced lymphomagenesis

Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells

(2012) D. Merino et al.   BLOOD

Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice

(2012) P N Kelly et al.   CELL DEATH AND DIFFERENTIATION

Endogenous Bcl-xL is essential for Myc-driven lymphomagenesis in mice

(2011) P. N. Kelly et al.   BLOOD

Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

(2011) Andreas Strasser et al.   EMBO JOURNAL

Maximal killing of lymphoma cells by DNA damage-inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim

(2010) L. Happo et al.   BLOOD

Apoptosis-promoted tumorigenesis:  -irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death

(2010) E. M. Michalak et al.   GENES & DEVELOPMENT

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis

(2009) E M Michalak et al.   CELL DEATH AND DIFFERENTIATION

Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates γ irradiation–induced thymic lymphoma development

(2008) Verena Labi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of BH3-only Protein Bim Inhibits Apoptosis of Hemopoietic Cells in the Fetal Liver and Male Germ Cells but Not Neuronal Cells in Bcl-x-deficient Mice

(2008) Rizwan S. Akhtar et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Selection against PUMA Gene Expression in Myc-Driven B-Cell Lymphomagenesis

(2008) S. P. Garrison et al.   MOLECULAR AND CELLULAR BIOLOGY