Contributions of DNA repair, cell cycle checkpoints and cell death to suppressing the DNA damage-induced tumorigenic behavior of Drosophila epithelial cells

Tumors of the testis and midgut in aging flies

(2014) Robert N. Salomon et al.   FLY

p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa

(2013) Liz J. Valente et al.   Cell Reports

Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence

(2012) Tongyuan Li et al.   CELL

Aneuploidy causes proteotoxic stress in yeast

(2012) A. B. Oromendia et al.   GENES & DEVELOPMENT

Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells

(2012) Silvia Stingele et al.   Molecular Systems Biology

Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila

(2012) Shizue Ohsawa et al.   NATURE

Chemical genetic discovery of targets and anti-targets for cancer polypharmacology

(2012) Arvin C. Dar et al.   NATURE

Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression

(2012) S. S. Foster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia

(2012) A. Dekanty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

(2011) Colleen A. Brady et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

DrosophilaATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair

(2011) Eric F. Joyce et al.   JOURNAL OF CELL BIOLOGY

Loss of the bloom syndrome helicase increases DNA ligase 4-independent genome rearrangements and tumorigenesis in aging Drosophila

(2011) Ana Garcia et al.   GENOME BIOLOGY

The Cdc42/Par6/aPKC Polarity Complex Regulates Apoptosis-Induced Compensatory Proliferation in Epithelia

(2010) Stephen J. Warner et al.   CURRENT BIOLOGY

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Age- and Temperature-Dependent Somatic Mutation Accumulation in Drosophila melanogaster

(2010) Ana Maria Garcia et al.   PLoS Genetics

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Role of H2AX in DNA damage response and human cancers

(2008) Niloo Srivastava et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE