LRH-1 controls proliferation in breast tumor cells by regulating CDKN1A gene expression

LRH-1 Governs Vital Transcriptional Programs in Endocrine-Sensitive and -Resistant Breast Cancer Cells

(2014) S. Bianco et al.   CANCER RESEARCH

The transcriptional co-repressor TLE3 suppresses basal signaling on a subset of estrogen receptor α target genes

(2014) Maïka Jangal et al.   NUCLEIC ACIDS RESEARCH

Oestradiol reduces Liver Receptor Homolog-1 mRNA transcript stability in breast cancer cell lines

(2013) Kyren A. Lazarus et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Distinct nuclear receptor expression in stroma adjacent to breast tumors

(2013) Kevin C. Knower et al.   BREAST CANCER RESEARCH AND TREATMENT

Breast cancer classification by proteomic technologies: Current state of knowledge

(2013) S.W. Lam et al.   CANCER TREATMENT REVIEWS

Nuclear Receptor LRH-1 Induces the Reproductive Neuropeptide Kisspeptin in the Hypothalamus

(2013) Stan D. Atkin et al.   MOLECULAR ENDOCRINOLOGY

Liver receptor homolog-1 is essential for pregnancy

(2013) Cong Zhang et al.   NATURE MEDICINE

Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells

(2013) Chun-Fui Lai et al.   NUCLEIC ACIDS RESEARCH

Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells

(2013) Deborah A Sanders et al.   GENOME BIOLOGY

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

(2012) Guoliang Li et al.   CELL

LRH-1–dependent glucose sensing determines intermediary metabolism in liver

(2012) Maaike H. Oosterveer et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapeutic potential of Liver Receptor Homolog-1 modulators

(2012) Kyren A. Lazarus et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

The Orphan Nuclear Receptor LRH-1 and ERα Activate GREB1 Expression to Induce Breast Cancer Cell Proliferation

(2012) Ashwini L. Chand et al.   PLoS One

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Colon cancer cells produce immunoregulatory glucocorticoids

(2012) Daniel Sidler et al.   OncoImmunology

H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic geneBCL2determines ERα ligand dependency

(2011) Amy Svotelis et al.   EMBO JOURNAL

LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function

(2011) S. R. Holmstrom et al.   GENES & DEVELOPMENT

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

(2011) Dong Wang et al.   NATURE

Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation

(2011) Nanping Ai et al.   NUCLEIC ACIDS RESEARCH

Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation

(2011) C. Benod et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue-specific regulation of aromatase promoter II by the orphan nuclear receptor LRH-1 in breast adipose stromal fibroblasts

(2011) Ashwini L. Chand et al.   STEROIDS

Mechanisms of Endocrine Resistance in Breast Cancer

(2010) C. Kent Osborne et al.   Annual Review of Medicine

The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells

(2010) Paul T. R. Thiruchelvam et al.   BREAST CANCER RESEARCH AND TREATMENT

Examination of the expanding pathways for the regulation of p21 expression and activity

(2010) Yong-Sam Jung et al.   CELLULAR SIGNALLING

The orphan nuclear receptor LRH-1 promotes breast cancer motility and invasion

(2010) A L Chand et al.   ENDOCRINE-RELATED CANCER

Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression

(2010) T. Yamaguchi et al.   GENES & DEVELOPMENT

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

FOXA1 is a key determinant of estrogen receptor function and endocrine response

(2010) Antoni Hurtado et al.   NATURE GENETICS

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

(2010) Francesca De Santa et al.   PLOS BIOLOGY

The Cyclin-Dependent Kinase Inhibitor p21 Is a Crucial Target for Histone Deacetylase 1 as a Regulator of Cellular Proliferation

(2009) G. Zupkovitz et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone modifications at human enhancers reflect global cell-type-specific gene expression

(2009) Nathaniel D. Heintzman et al.   NATURE

F-Seq: a feature density estimator for high-throughput sequence tags

(2008) A. P. Boyle et al.   BIOINFORMATICS

Liver receptor homolog 1 is essential for ovulation

(2008) R. Duggavathi et al.   GENES & DEVELOPMENT