Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5a

HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer

(2014) Manoj M. Pillai et al.   BREAST CANCER RESEARCH AND TREATMENT

Enhanced microRNA accumulation through stemloop-adjacent introns

(2013) Rebecca Schwab et al.   EMBO REPORTS

Prolactin suppresses a progestin-induced CK5-positive cell population in luminal breast cancer through inhibition of progestin-driven BCL6 expression

(2013) T Sato et al.   ONCOGENE

Progesterone/RANKL Is a Major Regulatory Axis in the Human Breast

(2013) T. Tanos et al.   Science Translational Medicine

Expression profiles of microRNAs from lactating and non-lactating bovine mammary glands and identification of miRNA related to lactation

(2012) Zhen Li et al.   BMC GENOMICS

Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures

(2012) Peter Kabos et al.   BREAST CANCER RESEARCH AND TREATMENT

Distinct microRNA Expression Profiles in Prostate Cancer Stem/Progenitor Cells and Tumor-Suppressive Functions of let-7

(2012) C. Liu et al.   CANCER RESEARCH

MicroRNA biogenesis: regulating the regulators

(2012) Emily F. Finnegan et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

MicroRNAs in the ImprintedDLK1-DIO3Region Repress the Epithelial-to-Mesenchymal Transition by Targeting the TWIST1 Protein Signaling Network

(2012) Christopher L. Haga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progestin regulated miRNAs that mediate progesterone receptor action in breast cancer

(2012) Dawn R. Cochrane et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4

(2012) D M Cittelly et al.   ONCOGENE

Progesterone-Inducible Cytokeratin 5-Positive Cells in Luminal Breast Cancer Exhibit Progenitor Properties

(2012) Sunshine Daddario Axlund et al.   Hormones & Cancer

The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors

(2011) E. A. Nelson et al.   BLOOD

An HNF4α-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis

(2011) Maria Hatziapostolou et al.   CELL

Stat5 assumes distinct functions in mammary gland development and mammary tumor formation

(2011) Vida Vafaizadeh   Frontiers in Bioscience-Landmark

The biology of progesterone receptor in the normal mammary gland and in breast cancer

(2011) Alison E. Obr et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The role of miRNAs in progesterone action

(2011) Dawn R. Cochrane et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation

(2011) Michael P. Gantier et al.   NUCLEIC ACIDS RESEARCH

Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

(2011) D. Iliopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers

(2010) Peter Kabos et al.   BREAST CANCER RESEARCH AND TREATMENT

Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis

(2010) Eva Gonzalez-Suarez et al.   NATURE

Control of mammary stem cell function by steroid hormone signalling

(2010) Marie-Liesse Asselin-Labat et al.   NATURE

Progesterone induces adult mammary stem cell expansion

(2010) Purna A. Joshi et al.   NATURE

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

(2010) Daniel Schramek et al.   NATURE

Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors

(2010) V. Rouet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

DNA Replication Licensing and Progenitor Numbers Are Increased by Progesterone in Normal Human Breast

(2009) J. Dinny Graham et al.   ENDOCRINOLOGY

Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A

(2009) D. Yamaji et al.   GENES & DEVELOPMENT

MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents

(2009) D. R. Cochrane et al.   MOLECULAR CANCER THERAPEUTICS

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

(2009) Saibal Chatterjee et al.   NATURE

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Progestins in Hormone Replacement Therapies Reactivate Cancer Stem Cells in Women with Preexisting Breast Cancers: A Hypothesis

(2008) Kathryn B. Horwitz et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Jak2/Stat5 Signaling in Mammogenesis, Breast Cancer Initiation and Progression

(2008) Kay-Uwe Wagner et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts

(2008) K. B. Horwitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen and Progesterone are Critical Regulators of Stat5a Expression in the Mouse Mammary Gland

(2007) Sarah J. Santos et al.   ENDOCRINOLOGY