SUPT6H controls estrogen receptor activity and cellular differentiation by multiple epigenomic mechanisms

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis

(2013) A Hongjun Wang et al.   EMBO JOURNAL

Histone H2B lysine 120 monoubiquitination is required for embryonic stem cell differentiation

(2012) Su Chen et al.   CELL RESEARCH

The enigmatic role of H2Bub1 in cancer

(2012) Steven A. Johnsen   FEBS LETTERS

The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation

(2012) S. Chen et al.   GENES & DEVELOPMENT

GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility

(2012) V. Theodorou et al.   GENOME RESEARCH

The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells

(2012) Oleksandra Karpiuk et al.   MOLECULAR CELL

RNF20 and USP44 Regulate Stem Cell Differentiation by Modulating H2B Monoubiquitylation

(2012) Gilad Fuchs et al.   MOLECULAR CELL

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

CDK9 and H2B Monoubiquitination: A Well-Choreographed Dance

(2012) Steven A. Johnsen   PLoS Genetics

Estrogen-Dependent Gene Transcription in Human Breast Cancer Cells Relies upon Proteasome-Dependent Monoubiquitination of Histone H2B

(2011) T. Prenzel et al.   CANCER RESEARCH

The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair

(2011) Vijayalakshmi Kari et al.   CELL CYCLE

WAC, a Functional Partner of RNF20/40, Regulates Histone H2B Ubiquitination and Gene Transcription

(2011) Feng Zhang et al.   MOLECULAR CELL

HEXIM1 is a critical determinant of the response to tamoxifen

(2011) W Ketchart et al.   ONCOGENE

Decreased expression of EZH2 is associated with upregulation of ER and favorable outcome to tamoxifen in advanced breast cancer

(2010) E. A. Reijm et al.   BREAST CANCER RESEARCH AND TREATMENT

Insights into the function of the human P-TEFb component CDK9 in the regulation of chromatin modifications and co-transcriptional mRNA processing

(2010) Judith Pirngruber et al.   CELL CYCLE

Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II

(2010) Marie-Laure Diebold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induced G1 cell-cycle arrest controls replication-dependent histone mRNA 3′ end processing through p21, NPAT and CDK9

(2010) J Pirngruber et al.   ONCOGENE

RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells

(2009) Jaehoon Kim et al.   CELL

CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3′-end processing

(2009) Judith Pirngruber et al.   EMBO REPORTS

An oestrogen-receptor-α-bound human chromatin interactome

(2009) Melissa J. Fullwood et al.   NATURE

HEXIM1 Regulates 17 -Estradiol/Estrogen Receptor- -Mediated Expression of Cyclin D1 in Mammary Cells via Modulation of P-TEFb

(2008) N. Ogba et al.   CANCER RESEARCH

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

(2008) E. Shema et al.   GENES & DEVELOPMENT

Postrecruitment Regulation of RNA Polymerase II Directs Rapid Signaling Responses at the Promoters of Estrogen Target Genes

(2008) M. Kininis et al.   MOLECULAR AND CELLULAR BIOLOGY

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

(2008) Neri Minsky et al.   NATURE CELL BIOLOGY

Stromal gene expression predicts clinical outcome in breast cancer

(2008) Greg Finak et al.   NATURE MEDICINE

Cracking the RNA polymerase II CTD code

(2008) Sylvain Egloff et al.   TRENDS IN GENETICS

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

(2008) Sami Kilpinen et al.   GENOME BIOLOGY