Comparison of gene expression patterns across 12 tumor types identifies a cancer supercluster characterized by TP53 mutations and cell cycle defects

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

The Somatic Genomic Landscape of Glioblastoma

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A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival

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Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

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Comprehensive molecular characterization of clear cell renal cell carcinoma

(2013)   NATURE

Temporal regulation of EGF signalling networks by the scaffold protein Shc1

(2013) Yong Zheng et al.   NATURE

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Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

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Nivolumab plus Ipilimumab in Advanced Melanoma

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Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

The Reactome pathway knowledgebase

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Data, information, knowledge and principle: back to metabolism in KEGG

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Inferring tumour purity and stromal and immune cell admixture from expression data

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Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

Absolute quantification of somatic DNA alterations in human cancer

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Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Subtype and pathway specific responses to anticancer compounds in breast cancer

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Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM

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Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

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Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

(2008) R. G.W. Verhaak et al.   HAEMATOLOGICA

Cyclin-Dependent Kinase-Associated Proteins Cks1 and Cks2 Are Essential during Early Embryogenesis and for Cell Cycle Progression in Somatic Cells

(2008) H.-S. Martinsson-Ahlzen et al.   MOLECULAR AND CELLULAR BIOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

PID: the Pathway Interaction Database

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