Identification of novel TMPRSS2:ERG mechanisms in prostate cancer metastasis: involvement of MMP9 and PLXNA2

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Integrin-linked kinase as a target for ERG-mediated invasive properties in prostate cancer models

(2012) D. D. Becker-Santos et al.   CARCINOGENESIS

A transcriptional repressor co-regulatory network governing androgen response in prostate cancers

(2012) Kern Rei Chng et al.   EMBO JOURNAL

Secreted Hsp90 Is a Novel Regulator of the Epithelial to Mesenchymal Transition (EMT) in Prostate Cancer

(2012) Michael W. Hance et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Transcription Factor SPDEF Suppresses Prostate Tumor Metastasis

(2012) Joshua J. Steffan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Marked heterogeneity of ERG expression in large primary prostate cancers

(2012) Sarah Minner et al.   MODERN PATHOLOGY

Effect of cancer-associated mutations in the PlexinB1 gene

(2012) Chun Zhou et al.   Molecular Cancer

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

ETS1 promotes chemoresistance and invasion of paclitaxel-resistant, hormone-refractory PC3 prostate cancer cells by up-regulating MDR1 and MMP9 expression

(2011) Taku Kato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The relationship of TMPRSS2-ERG gene fusion between primary and metastatic prostate cancers

(2011) Charles C. Guo et al.   HUMAN PATHOLOGY

End Points and Outcomes in Castration-Resistant Prostate Cancer: From Clinical Trials to Clinical Practice

(2011) Howard I. Scher et al.   JOURNAL OF CLINICAL ONCOLOGY

Common Gene Rearrangements in Prostate Cancer

(2011) Mark A. Rubin et al.   JOURNAL OF CLINICAL ONCOLOGY

ERG immunohistochemistry is not predictive for PSA recurrence, local recurrence or overall survival after radical prostatectomy for prostate cancer

(2011) A Marije Hoogland et al.   MODERN PATHOLOGY

TMPRSS2/ERG Promotes Epithelial to Mesenchymal Transition through the ZEB1/ZEB2 Axis in a Prostate Cancer Model

(2011) Orit Leshem et al.   PLoS One

An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression

(2010) Jindan Yu et al.   CANCER CELL

FZD4 as a Mediator of ERG Oncogene-Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

(2010) S. Gupta et al.   CANCER RESEARCH

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

(2010) Gong-Hong Wei et al.   EMBO JOURNAL

Multifocal prostate cancer: biologic, prognostic, and therapeutic implications

(2010) Matei Andreoiu et al.   HUMAN PATHOLOGY

ETS Transcription Factors Control Transcription of EZH2 and Epigenetic Silencing of the Tumor Suppressor Gene Nkx3.1 in Prostate Cancer

(2010) Paolo Kunderfranco et al.   PLoS One

A role for class 3 semaphorins in prostate cancer

(2010) V. Blanc et al.   PROSTATE

ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification

(2010) B Furusato et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Isolation and Characterization of Circulating Tumor Cells from Patients with Localized and Metastatic Prostate Cancer

(2010) S. L. Stott et al.   Science Translational Medicine

TMPRSS2-ERG Gene Fusion Is Not Associated with Outcome in Patients Treated by Prostatectomy

(2009) Anuradha Gopalan et al.   CANCER RESEARCH

Characterization of ERG, AR and PTEN Gene Status in Circulating Tumor Cells from Patients with Castration-Resistant Prostate Cancer

(2009) G. Attard et al.   CANCER RESEARCH

Overexpression of Prostate-Specific TMPRSS2(exon 0)-ERG Fusion Transcripts Corresponds with Favorable Prognosis of Prostate Cancer

(2009) K. G. Hermans et al.   CLINICAL CANCER RESEARCH

Identification of four alternatively spliced transcripts of the Ucma/GRP gene, encoding a new Gla-containing protein☆

(2009) Marion Le Jeune et al.   EXPERIMENTAL CELL RESEARCH

Semaphorin signaling in cancer cells and in cells of the tumor microenvironment - two sides of a coin

(2009) L. Capparuccia et al.   JOURNAL OF CELL SCIENCE

RREB-1 Is a Transcriptional Repressor of HLA-G

(2009) S. Flajollet et al.   JOURNAL OF IMMUNOLOGY

Genetic Polymorphisms of Matrix Metalloproteinases: Susceptibility and Prognostic Implications for Prostate Cancer

(2009) Sabrina Thalita dos Reis et al.   JOURNAL OF UROLOGY

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

(2009) Jennifer C King et al.   NATURE GENETICS

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

(2009) Brett S Carver et al.   NATURE GENETICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

(2009) Y. Zong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling

(2009) K. Kodo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERG Rearrangement Metastasis Patterns in Locally Advanced Prostate Cancer

(2009) Sven Perner et al.   UROLOGY

Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer

(2008) Liesel M FitzGerald et al.   BMC CANCER

Pleiotropic Biological Activities of Alternatively Spliced TMPRSS2/ERG Fusion Gene Transcripts

(2008) J. Wang et al.   CANCER RESEARCH

Characterization of TMPRSS2-ETS Gene Aberrations in Androgen-Independent Metastatic Prostate Cancer

(2008) R. Mehra et al.   CANCER RESEARCH

TMPRSS2:ERG Fusion Identifies a Subgroup of Prostate Cancers with a Favorable Prognosis

(2008) O. R. Saramaki et al.   CLINICAL CANCER RESEARCH

Activation of the Osteopontin/Matrix Metalloproteinase-9 Pathway Correlates with Prostate Cancer Progression

(2008) G. Castellano et al.   CLINICAL CANCER RESEARCH

Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells

(2008) Toshihiko Toyofuku et al.   DEVELOPMENTAL BIOLOGY

Tyrosine phosphorylation in semaphorin signalling: shifting into overdrive

(2008) Mélanie Franco et al.   EMBO REPORTS

The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA

(2008) Mika Sakurai-Yageta et al.   JOURNAL OF CELL BIOLOGY

A causal role for ERG in neoplastic transformation of prostate epithelium

(2008) O. Klezovitch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

(2008) Scott A. Tomlins et al.   NEOPLASIA