EVI1 oncogene promotes KRAS pathway through suppression of microRNA-96 in pancreatic carcinogenesis

Evi1 forms a bridge between the epigenetic machinery and signaling pathways

(2015) Akihide Yoshimi et al.   Oncotarget

Presence of Somatic Mutations in Most Early-Stage Pancreatic Intraepithelial Neoplasia

(2012) Mitsuro Kanda et al.   GASTROENTEROLOGY

Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins

(2011) A. Yoshimi et al.   BLOOD

miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma

(2011) H. Matsuyama et al.   BLOOD

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

(2011) An De Weer et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Evi1, microRNA-143, K-Ras axis in colon cancer

(2011) Jin-Song Gao et al.   FEBS LETTERS

Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia

(2011) I. Vazquez et al.   HAEMATOLOGICA

Claudin-18 Is an Early-Stage Marker of Pancreatic Carcinogenesis

(2011) Mariko Tanaka et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

(2011) Eric A Collisson et al.   NATURE MEDICINE

The Oncoprotein EVI1 and the DNA Methyltransferase Dnmt3 Co-Operate in Binding and De Novo Methylation of Target DNA

(2011) Vitalyi Senyuk et al.   PLoS One

miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras

(2010) Ki-Hyuk Shin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2

(2010) M Gómez-Benito et al.   BRITISH JOURNAL OF CANCER

miRNA-96 Suppresses KRAS and Functions as a Tumor Suppressor Gene in Pancreatic Cancer

(2010) S. Yu et al.   CANCER RESEARCH

Loss of FOXA1/2 Is Essential for the Epithelial-to-Mesenchymal Transition in Pancreatic Cancer

(2010) Y. Song et al.   CANCER RESEARCH

Emerging complexity of microRNA generation cascades

(2010) H. I. Suzuki et al.   JOURNAL OF BIOCHEMISTRY

Dynamics of microRNA biogenesis: crosstalk between p53 network and microRNA processing pathway

(2010) Hiroshi I. Suzuki et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A Link between mir-100 and FRAP1/mTOR in Clear Cell Ovarian Cancer

(2010) Ankur K. Nagaraja et al.   MOLECULAR ENDOCRINOLOGY

Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome

(2010) J. Dickstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunohistochemical Staining of Reg IV and Claudin-18 is Useful in the Diagnosis of Gastrointestinal Signet Ring Cell Carcinoma

(2009) Kazuhiro Sentani et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Pathogenetic significance of ecotropic viral integration site-1 in hematological malignancies

(2009) Susumu Goyama et al.   CANCER SCIENCE

Ras Activity in Acinar Cells Links Chronic Pancreatitis and Pancreatic Cancer

(2009) Craig D. Logsdon et al.   Clinical Gastroenterology and Hepatology

Ras Activity Levels Control the Development of Pancreatic Diseases

(2009) Baoan Ji et al.   GASTROENTEROLOGY

Significance of mucin expression in pancreatobiliary neoplasms

(2009) Suguru Yonezawa et al.   Journal of Hepato-Biliary-Pancreatic Sciences

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Role of miR-143 targeting KRAS in colorectal tumorigenesis

(2009) X Chen et al.   ONCOGENE

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

(2008) J.-P. De La O et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Profiling Identifies GATA6 as a Candidate Oncogene Amplified in Pancreatobiliary Cancer

(2008) Kevin A. Kwei et al.   PLoS Genetics