Mode of action of trabectedin in myxoid liposarcomas

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

(2013) Giovanni Germano et al.   CANCER CELL

PPARγ agonists enhance ET-743–induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma

(2012) Elizabeth Charytonowicz et al.   JOURNAL OF CLINICAL INVESTIGATION

Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model

(2012) Elizabeth G Demicco et al.   MODERN PATHOLOGY

Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma

(2011) A. Gronchi et al.   ANNALS OF ONCOLOGY

Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells

(2010) G. Germano et al.   CANCER RESEARCH

Functional Mapping of Receptor Tyrosine Kinases in Myxoid Liposarcoma

(2010) T. Negri et al.   CLINICAL CANCER RESEARCH

Novel Models of Myxoid Liposarcoma Xenografts Mimicking the Biological and Pharmacologic Features of Human Tumors

(2010) R. Frapolli et al.   CLINICAL CANCER RESEARCH

Detection of myxoid liposarcoma-associated FUS–DDIT3 rearrangement variants including a newly identified breakpoint using an optimized RT-PCR assay

(2010) Martin P Powers et al.   MODERN PATHOLOGY

A Review of Trabectedin (ET-743): A Unique Mechanism of Action

(2010) Maurizio D'Incalci et al.   MOLECULAR CANCER THERAPEUTICS

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

(2010) Jordi Barretina et al.   NATURE GENETICS

Trabectedin in myxoid liposarcomas (MLS): a long-term analysis of a single-institution series

(2009) F. Grosso et al.   ANNALS OF ONCOLOGY

Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors

(2009) C. Forni et al.   MOLECULAR CANCER THERAPEUTICS

Role of homologous recombination in trabectedin-induced DNA damage

(2008) M. Tavecchio et al.   EUROPEAN JOURNAL OF CANCER

FUS-DDIT3 Prevents the Development of Adipocytic Precursors in Liposarcoma by Repressing PPARγ and C/EBPα and Activating eIF4E

(2008) Pedro A. Pérez-Mancera et al.   PLoS One