Integrin α3β1–CD151 complex regulates dimerization of ErbB2 via RhoA

Integrin-Associated CD151 Drives ErbB2-Evoked Mammary Tumor Onset and Metastasis

(2015) Xinyu Deng et al.   NEOPLASIA

Clinical significance of CD151 overexpression in subtypes of invasive breast cancer

(2012) M J Kwon et al.   BRITISH JOURNAL OF CANCER

Tetraspanin CD151 Stimulates Adhesion-dependent Activation of Ras, Rac, and Cdc42 by Facilitating Molecular Association between β1Integrins and Small GTPases

(2012) In-Kee Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α3β1 integrins regulate CD151 complex assembly and membrane dynamics in carcinoma cells within 3D environments

(2012) T M E Scales et al.   ONCOGENE

The effect of cell–ECM adhesion on signalling via the ErbB family of growth factor receptors

(2011) Xanthippi Alexi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

GxxxG Motifs, Phenylalanine, and Cholesterol Guide the Self-Association of Transmembrane Domains of ErbB2 Receptors

(2011) Anupam Prakash et al.   BIOPHYSICAL JOURNAL

Tetraspanin CD151 maintains vascular stability by balancing the forces of cell adhesion and cytoskeletal tension

(2011) F. Zhang et al.   BLOOD

Trastuzumab Has Preferential Activity against Breast Cancers Driven by HER2 Homodimers

(2011) R. Ghosh et al.   CANCER RESEARCH

Treatment of HER2-positive breast cancer: current status and future perspectives

(2011) Carlos L. Arteaga et al.   Nature Reviews Clinical Oncology

Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+breast cancer patients

(2011) Maurizio Scaltriti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tetraspanin CD151 Regulates Growth of Mammary Epithelial Cells in Three-Dimensional Extracellular Matrix: Implication for Mammary Ductal Carcinoma In situ

(2010) Vera Novitskaya et al.   CANCER RESEARCH

Disruption of Laminin-Integrin-CD151-Focal Adhesion Kinase Axis Sensitizes Breast Cancer Cells to ErbB2 Antagonists

(2010) X. H. Yang et al.   CANCER RESEARCH

Laminin-binding integrins and their tetraspanin partners as potential antimetastatic targets

(2010) Christopher S. Stipp   EXPERT REVIEWS IN MOLECULAR MEDICINE

ErbB2 requires integrin  5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells

(2010) K. K. Haenssen et al.   JOURNAL OF CELL SCIENCE

The α2β1 integrin is a metastasis suppressor in mouse models and human cancer

(2010) Norma E. Ramirez et al.   JOURNAL OF CLINICAL INVESTIGATION

Loss of Phosphatase and Tensin Homolog or Phosphoinositol-3 Kinase Activation and Response to Trastuzumab or Lapatinib in Human Epidermal Growth Factor Receptor 2–Overexpressing Locally Advanced Breast Cancers

(2010) Bhuvanesh Dave et al.   JOURNAL OF CLINICAL ONCOLOGY

 1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression

(2010) L. Huck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

(2009) Britta Weigelt et al.   BREAST CANCER RESEARCH AND TREATMENT

 1-Integrin Circumvents the Antiproliferative Effects of Trastuzumab in Human Epidermal Growth Factor Receptor-2-Positive Breast Cancer

(2009) D. Lesniak et al.   CANCER RESEARCH

Immunoselection of Breast and Ovarian Cancer Cells with Trastuzumab and Natural Killer Cells: Selective Escape of CD44high/CD24low/HER2low Breast Cancer Stem Cells

(2009) F. Reim et al.   CANCER RESEARCH

Transforming Growth Factor   Induces Clustering of HER2 and Integrins by Activating Src-Focal Adhesion Kinase and Receptor Association to the Cytoskeleton

(2009) S. E. Wang et al.   CANCER RESEARCH

ErbB receptors and signaling pathways in cancer

(2009) Nancy E Hynes et al.   CURRENT OPINION IN CELL BIOLOGY

Distinct Roles for RhoVersusRac/Cdc42 GTPases Downstream of Vav2 in Regulating Mammary Epithelial Acinar Architecture

(2009) Lei Duan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD151 Regulates Tumorigenesis by Modulating the Communication between Tumor Cells and Endothelium

(2009) R. Sadej et al.   MOLECULAR CANCER RESEARCH

Functional Characterization of Integrin α6β4 Adhesion Interactions Using Soluble Integrin Constructs Reveals the Involvement of Different Functional Domains in the β4 Subunit

(2008) Ling Ling Chen et al.   CELL COMMUNICATION AND ADHESION

RhoA/ROCK I signalling downstream of the P2Y13 ADP-receptor controls HDL endocytosis in human hepatocytes

(2008) C MALAVAL et al.   CELLULAR SIGNALLING

Ligand-induced ErbB receptor dimerization

(2008) Mark A. Lemmon   EXPERIMENTAL CELL RESEARCH

Tetraspanin CD151 Regulates Glycosylation of α3β1 Integrin

(2008) Gouri Baldwin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantification of integrin receptor agonism by fluorescence lifetime imaging

(2008) M. Parsons et al.   JOURNAL OF CELL SCIENCE