TMPRSS2–ERG gene fusions induce prostate tumorigenesis by modulating microRNA miR-200c

The proto-oncogene ERG is a target of microRNAmiR-145in prostate cancer

(2013) Martin Hart et al.   FEBS Journal

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

(2013) Changmeng Cai et al.   JOURNAL OF CLINICAL INVESTIGATION

Roles of microRNAs during prostatic tumorigenesis and tumor progression

(2013) Y-X Fang et al.   ONCOGENE

Epithelial-to-Mesenchymal Transition Leads to Docetaxel Resistance in Prostate Cancer and Is Mediated by Reduced Expression of miR-200c and miR-205

(2012) Martin Puhr et al.   AMERICAN JOURNAL OF PATHOLOGY

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Integrin-linked kinase as a target for ERG-mediated invasive properties in prostate cancer models

(2012) D. D. Becker-Santos et al.   CARCINOGENESIS

Restoration of miR-200c to Ovarian Cancer Reduces Tumor Burden and Increases Sensitivity to Paclitaxel

(2012) D. M. Cittelly et al.   MOLECULAR CANCER THERAPEUTICS

IL6-Mediated Suppression of miR-200c Directs Constitutive Activation of Inflammatory Signaling Circuit Driving Transformation and Tumorigenesis

(2012) Matjaz Rokavec et al.   MOLECULAR CELL

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

MicroRNA-34a Modulates c-Myc Transcriptional Complexes to Suppress Malignancy in Human Prostate Cancer Cells

(2012) Soichiro Yamamura et al.   PLoS One

miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression

(2012) Florian Kopp et al.   PLoS One

Coordinated Regulation of Polycomb Group Complexes through microRNAs in Cancer

(2011) Qi Cao et al.   CANCER CELL

Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer

(2011) J. Chad Brenner et al.   CANCER CELL

EMT and Stem Cell-Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells

(2011) C. S. Tellez et al.   CANCER RESEARCH

Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells

(2011) Diana M Vallejo et al.   EMBO JOURNAL

Cooperation between Polycomb and androgen receptor during oncogenic transformation

(2011) J. C. Zhao et al.   GENOME RESEARCH

p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs

(2011) Chun-Ju Chang et al.   NATURE CELL BIOLOGY

TMPRSS2/ERG Promotes Epithelial to Mesenchymal Transition through the ZEB1/ZEB2 Axis in a Prostate Cancer Model

(2011) Orit Leshem et al.   PLoS One

An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression

(2010) Jindan Yu et al.   CANCER CELL

FZD4 as a Mediator of ERG Oncogene-Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

(2010) S. Gupta et al.   CANCER RESEARCH

Activation of NF-κB by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4

(2010) Jianghua Wang et al.   CANCER RESEARCH

Molecular genetics of prostate cancer: new prospects for old challenges

(2010) M. M. Shen et al.   GENES & DEVELOPMENT

On the detection and refinement of transcription factor binding sites using ChIP-Seq data

(2010) Ming Hu et al.   NUCLEIC ACIDS RESEARCH

Role for DNA Methylation in the Regulation of miR-200c and miR-141 Expression in Normal and Cancer Cells

(2010) Lukas Vrba et al.   PLoS One

ETS Transcription Factors Control Transcription of EZH2 and Epigenetic Silencing of the Tumor Suppressor Gene Nkx3.1 in Prostate Cancer

(2010) Paolo Kunderfranco et al.   PLoS One

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy

(2009) L. Adam et al.   CLINICAL CANCER RESEARCH

MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets

(2009) Raffaele Baffa et al.   JOURNAL OF PATHOLOGY

ETS rearrangements and prostate cancer initiation

(2009) Brett S. Carver et al.   NATURE

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

Pleiotropic Biological Activities of Alternatively Spliced TMPRSS2/ERG Fusion Gene Transcripts

(2008) J. Wang et al.   CANCER RESEARCH

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

microRNAs and prostate cancer

(2008) Xu-Bao Shi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation

(2008) C Sun et al.   ONCOGENE

A causal role for ERG in neoplastic transformation of prostate epithelium

(2008) O. Klezovitch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A microRNA DNA methylation signature for human cancer metastasis

(2008) A. Lujambio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normalization of microRNA expression levels in quantitative RT-PCR assays: Identification of suitable reference RNA targets in normal and cancerous human solid tissues

(2008) H. J. Peltier et al.   RNA

Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

(2008) Scott A. Tomlins et al.   NEOPLASIA