PTEN ablation in Ras Ha /Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition

Proteomic Identification of a Direct Role for Cyclin D1 in DNA Damage Repair

(2012) S. Jirawatnotai et al.   CANCER RESEARCH

Intratumor Heterogeneity: Evolution through Space and Time

(2012) C. Swanton   CANCER RESEARCH

Pten Loss and RAS/MAPK Activation Cooperate to Promote EMT and Metastasis Initiated from Prostate Cancer Stem/Progenitor Cells

(2012) D. J. Mulholland et al.   CANCER RESEARCH

p21WAF1 and tumourigenesis

(2012) Noel A. Warfel et al.   CURRENT OPINION IN ONCOLOGY

Defining the mode of tumour growth by clonal analysis

(2012) Gregory Driessens et al.   NATURE

PTEN Protein Phosphatase Activity Correlates with Control of Gene Expression and Invasion, a Tumor-Suppressing Phenotype, But Not with AKT Activity

(2012) P. Tibarewal et al.   Science Signaling

Hallmarks of cancer: of all cancer cells, all the time?

(2012) Sébastien L. Floor et al.   TRENDS IN MOLECULAR MEDICINE

Accurate Reconstruction of the Temporal Order of Mutations in Neoplastic Progression

(2011) Kathleen Sprouffske et al.   Cancer Prevention Research

Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer

(2011) N. J. Birkbak et al.   CANCER RESEARCH

PTEN Positively Regulates UVB-Induced DNA Damage Repair

(2011) M. Ming et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Myc, Aurora Kinase A and mutant p53 R172H co-operate in a mouse model of metastatic skin carcinoma

(2011) E C Torchia et al.   ONCOGENE

Intrinsic Cooperation between p16INK4a and p21Waf1/Cip1 in the Onset of Cellular Senescence and Tumor Suppression In vivo

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Selective activation of p53-mediated tumour suppression in high-grade tumours

(2010) Melissa R. Junttila et al.   NATURE

p53 Deficiency Leads to Compensatory Up-Regulation of p16INK4a

(2009) W. F. Leong et al.   MOLECULAR CANCER RESEARCH

CDK2 Activation in Mouse Epidermis Induces Keratinocyte Proliferation but Does Not Affect Skin Tumor Development

(2008) Everardo Macias et al.   AMERICAN JOURNAL OF PATHOLOGY

Fos cooperation with PTEN loss elicits keratoacanthoma not carcinoma, owing to p53/p21WAF-induced differentiation triggered by GSK3  inactivation and reduced AKT activity

(2008) D. Yao et al.   JOURNAL OF CELL SCIENCE

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY