BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signaling

Microtubules Regulate Hypoxia-inducible Factor-1α Protein Trafficking and Activity

(2012) Marisa Carbonaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma

(2012) Jessica N McAlpine et al.   MODERN PATHOLOGY

Axon injury and stress trigger a microtubule-based neuroprotective pathway

(2012) L. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Farnesyl transferase expression determines clinical response to the docetaxel-lonafarnib combination in patients with advanced malignancies

(2011) John Kauh et al.   CANCER

Taxane-Induced Blockade to Nuclear Accumulation of the Androgen Receptor Predicts Clinical Responses in Metastatic Prostate Cancer

(2011) M. S. Darshan et al.   CANCER RESEARCH

Predictive impact of DNA repair functionality on clinical outcome of advanced sarcoma patients treated with trabectedin: A retrospective multicentric study

(2011) P. Schöffski et al.   EUROPEAN JOURNAL OF CANCER

A novel role for BRCA1 in regulating breast cancer cell spreading and motility

(2011) Elisabeth D. Coene et al.   JOURNAL OF CELL BIOLOGY

Microtubule disruption targets HIF-1α mRNA to cytoplasmic P-bodies for translational repression

(2011) Marisa Carbonaro et al.   JOURNAL OF CELL BIOLOGY

mRNA Expression of BRCA1, PIAS1, and PIAS4 and Survival After Second-line Docetaxel in Advanced Gastric Cancer

(2011) Jia Wei et al.   JNCI-Journal of the National Cancer Institute

Mitosis is not a key target of microtubule agents in patient tumors

(2011) Edina Komlodi-Pasztor et al.   Nature Reviews Clinical Oncology

BRCA1 mRNA expression and outcome to neoadjuvant cisplatin-based chemotherapy in bladder cancer

(2010) A. Font et al.   ANNALS OF ONCOLOGY

Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability

(2010) Claudio R. Thoma et al.   JOURNAL OF CELL BIOLOGY

Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer

(2010) Bryan T.J. Hennessy et al.   JOURNAL OF CLINICAL ONCOLOGY

Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial

(2010) Johann Sebastian de Bono et al.   LANCET

Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling

(2010) Guoqiang Xu et al.   NATURE BIOTECHNOLOGY

Adjuvant Docetaxel for High-Risk, Node-Negative Breast Cancer

(2010) Miguel Martín et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hereditary Breast Cancer: Part I. Diagnosing Hereditary Breast Cancer Syndromes

(2009) Henry T. Lynch et al.   Breast Journal

From signaling pathways to microtubule dynamics: the key players

(2009) Sandrine Etienne-Manneville   CURRENT OPINION IN CELL BIOLOGY

The BRCA1-dependent ubiquitin ligase, γ-tubulin, and centrosomes

(2009) Jeffrey D. Parvin   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The Protein Farnesyltransferase Regulates HDAC6 Activity in a Microtubule-dependent Manner

(2009) Jun Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BRCA1 Interaction of Centrosomal Protein Nlp Is Required for Successful Mitotic Progression

(2009) Shunqian Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

γ-Tubulin ring complexes regulate microtubule plus end dynamics

(2009) Anaïs Bouissou et al.   JOURNAL OF CELL BIOLOGY

Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules

(2009) A Mielgo et al.   ONCOGENE

Customized Treatment in Non-Small-Cell Lung Cancer Based on EGFR Mutations and BRCA1 mRNA Expression

(2009) Rafael Rosell et al.   PLoS One

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

BRCA1: A New Genomic Marker for Non–Small-Cell Lung Cancer

(2008) Noemí Reguart et al.   Clinical Lung Cancer