Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities

ROCK1 and ROCK2 Are Required for Non-Small Cell Lung Cancer Anchorage-Independent Growth and Invasion

(2012) D. Vigil et al.   CANCER RESEARCH

RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

(2012) R. A. Patel et al.   CANCER RESEARCH

Fragment-Based and Structure-Guided Discovery and Optimization of Rho Kinase Inhibitors

(2012) Rongshi Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Combination of Farnesyltransferase and Akt Inhibitors Is Synergistic in Breast Cancer Cells and Causes Significant Breast Tumor Regression in ErbB2 Transgenic Mice

(2011) M. E. Balasis et al.   CLINICAL CANCER RESEARCH

Inhibition of Rho-Associated Kinase Signaling Prevents Breast Cancer Metastasis to Human Bone

(2009) S. Liu et al.   CANCER RESEARCH

The actin cytoskeleton in cancer cell motility

(2008) Michael F. Olson et al.   CLINICAL & EXPERIMENTAL METASTASIS

Applications for ROCK kinase inhibition

(2008) Michael F Olson   CURRENT OPINION IN CELL BIOLOGY

Role of Rho GTPases in breast cancer

(2007) Yong Tang   Frontiers in Bioscience-Landmark