Chromatin effector Pygo2 regulates mammary tumor initiation and heterogeneity in MMTV-Wnt1 mice

Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells

(2012) Bingnan Gu et al.   CELL CYCLE

Activation Status of Wnt/ß-Catenin Signaling in Normal and Neoplastic Breast Tissues: Relationship to HER2/neu Expression in Human and Mouse

(2012) Sara Khalil et al.   PLoS One

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

(2011) Piyush B. Gupta et al.   CELL

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

Distinct stem cells contribute to mammary gland development and maintenance

(2011) Alexandra Van Keymeulen et al.   NATURE

The cancer stem cell: premises, promises and challenges

(2011) Hans Clevers   NATURE MEDICINE

Integrated morphodynamic signalling of the mammary gland

(2011) Nikolce Gjorevski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differentiation Generates Paracrine Cell Pairs That Maintain Basaloid Mouse Mammary Tumors: Proof of Concept

(2011) Soyoung Kim et al.   PLoS One

Insights into the cell of origin in breast cancer and breast cancer stem cells

(2010) Geoffrey J LINDEMAN et al.   Asia-Pacific Journal of Clinical Oncology

Hedgehog pathway activation in chronic myeloid leukemia: A promise for a novel combination therapeutic approach?

(2010) Zainab Jagani et al.   CELL CYCLE

Epithelial stem cells: An epigenetic and wnt-centric perspective

(2010) Bingnan Gu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pygo2 Associates with MLL2 Histone Methyltransferase and GCN5 Histone Acetyltransferase Complexes To Augment Wnt Target Gene Expression and Breast Cancer Stem-Like Cell Expansion

(2010) J. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

(2010) Curtis A Thorne et al.   Nature Chemical Biology

Pea3 Transcription Factors and Wnt1-Induced Mouse Mammary Neoplasia

(2010) Rebecca Baker et al.   PLoS One

The transcriptional activity of Pygopus is enhanced by its interaction with cAMP-response-element-binding protein (CREB)-binding protein

(2009) Phillip G. P. Andrews et al.   BIOCHEMICAL JOURNAL

The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells

(2009) Angelo Cicalese et al.   CELL

Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis

(2009) Jane E. Visvader   GENES & DEVELOPMENT

Cytokeratin expression during mouse embryonic and early postnatal mammary gland development

(2009) Peng Sun et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation

(2009) Bingnan Gu et al.   JOURNAL OF CELL BIOLOGY

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

MMTV-Wnt1 and -ΔN89β-Catenin Induce Canonical Signaling in Distinct Progenitors and Differentially Activate Hedgehog Signaling within Mammary Tumors

(2009) Brigitte Teissedre et al.   PLoS One

The Mammary Progenitor Marker CD61/ 3 Integrin Identifies Cancer Stem Cells in Mouse Models of Mammary Tumorigenesis

(2008) F. Vaillant et al.   CANCER RESEARCH

Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex

(2008) Marc Fiedler et al.   MOLECULAR CELL

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

(2008) Wei Guo et al.   NATURE