Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation

Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate

(2011) Theresa A. Proia et al.   Cell Stem Cell

Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation

(2011) Y.-H. Lee et al.   GENES & DEVELOPMENT

Distinct stem cells contribute to mammary gland development and maintenance

(2011) Alexandra Van Keymeulen et al.   NATURE

BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers

(2011) D Tkocz et al.   ONCOGENE

Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells

(2011) J. I. Herschkowitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BRCA1 Tumor Suppression Depends on BRCT Phosphoprotein Binding, But Not Its E3 Ligase Activity

(2011) R. Shakya et al.   SCIENCE

BRD7, a Subunit of SWI/SNF Complexes, Binds Directly to BRCA1 and Regulates BRCA1-Dependent Transcription

(2010) M. T. Harte et al.   CANCER RESEARCH

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

(2010) Gemma Molyneux et al.   Cell Stem Cell

FOXA1 is an essential determinant of ER  expression and mammary ductal morphogenesis

(2010) G. M. Bernardo et al.   DEVELOPMENT

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit

(2010) C E Smart et al.   ONCOGENE

BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer

(2009) Julia J. Gorski et al.   BREAST CANCER RESEARCH AND TREATMENT

Preclinical mouse models for BRCA1-associated breast cancer

(2009) R M Drost et al.   BRITISH JOURNAL OF CANCER

CDK Inhibitor p18INK4c Is a Downstream Target of GATA3 and Restrains Mammary Luminal Progenitor Cell Proliferation and Tumorigenesis

(2009) Xin-Hai Pei et al.   CANCER CELL

Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A

(2009) D. Yamaji et al.   GENES & DEVELOPMENT

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

Mixed epithelial/mesenchymal metaplastic carcinoma (carcinosarcoma) of the breast in BRCA1 carrier

(2009) Evgeny N. Suspitsin et al.   Breast Cancer

Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development

(2008) Ruprecht Wiedemeyer et al.   CANCER CELL

Deletions of CDKN2C in Multiple Myeloma: Biological and Clinical Implications

(2008) P. E. Leone et al.   CLINICAL CANCER RESEARCH

Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1

(2008) Mollie H Wright et al.   Molecular Cancer

BRCA1 regulates human mammary stem/progenitor cell fate

(2008) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA