Ikaros represses and activates PU.1 cell-type-specifically through the multifunctional Sfpi1 URE and a myeloid specific enhancer

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

(2011) M. Leddin et al.   BLOOD

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

(2010) Sebastian Carotta et al.   IMMUNITY

Cell-Type-Specific Activation and Repression of PU.1 by a Complex of Discrete, Functionally Specialized cis-Regulatory Elements

(2010) M. A. Zarnegar et al.   MOLECULAR AND CELLULAR BIOLOGY

Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate

(2009) S. T. Chou et al.   BLOOD

Genome-wide Lineage-Specific Transcriptional Networks Underscore Ikaros-Dependent Lymphoid Priming in Hematopoietic Stem Cells

(2009) Samuel Yao-Ming Ng et al.   IMMUNITY

A Recurrent Network Involving the Transcription Factors PU.1 and Gfi1 Orchestrates Innate and Adaptive Immune Cell Fates

(2009) Chauncey J. Spooner et al.   IMMUNITY

Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c

(2009) Sandra Stehling-Sun et al.   NATURE IMMUNOLOGY

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element

(2008) A. K. Ebralidze et al.   GENES & DEVELOPMENT

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros

(2008) Damien Reynaud et al.   NATURE IMMUNOLOGY