Ribosomal protein S14 unties the MDM2–p53 loop upon ribosomal stress

Interplay between Ribosomal Protein S27a and MDM2 Protein in p53 Activation in Response to Ribosomal Stress

(2011) Xiao-Xin Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11

(2011) Masato Sasaki et al.   NATURE MEDICINE

Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells

(2010) S. Dutt et al.   BLOOD

Ribosomopathies: human disorders of ribosome dysfunction

(2010) A. Narla et al.   BLOOD

An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction

(2010) Everardo Macias et al.   CANCER CELL

Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase

(2010) Hiroyuki Inuzuka et al.   CANCER CELL

Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway

(2010) Susana Llanos et al.   CELL CYCLE

Defects in 18 S or 28 S rRNA Processing Activate the p53 Pathway

(2010) Michael Hölzel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perturbation of 60 S Ribosomal Biogenesis Results in Ribosomal Protein L5- and L11-dependent p53 Activation

(2010) Xiao-Xin Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

The C terminus of p53 binds the N-terminal domain of MDM2

(2010) Masha V Poyurovsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53–MDM2 loop

(2010) Weishi Yu et al.   NUCLEIC ACIDS RESEARCH

Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26

(2010) Y. Zhang et al.   NUCLEIC ACIDS RESEARCH

Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulator

(2010) X Xiong et al.   ONCOGENE

Signaling to p53: Ribosomal Proteins Find Their Way

(2009) Yanping Zhang et al.   CANCER CELL

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain

(2009) Sridevi Yadavilli et al.   DNA REPAIR

Regulation of nucleolar signalling to p53 through NEDDylation of L11

(2009) Anders Sundqvist et al.   EMBO REPORTS

Identification of mutations in the ribosomal protein L5 (RPL5) and ribosomal protein L11 (RPL11) genes in Czech patients with Diamond-Blackfan anemia

(2009) Radek Cmejla et al.   HUMAN MUTATION

Ribosomal Protein S7 Is Both a Regulator and a Substrate of MDM2

(2009) Yan Zhu et al.   MOLECULAR CELL

Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction

(2009) Stefano Fumagalli et al.   NATURE CELL BIOLOGY

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q– syndrome

(2009) Jillian L Barlow et al.   NATURE MEDICINE

Ribosomal Protein L5 and L11 Mutations Are Associated with Cleft Palate and Abnormal Thumbs in Diamond-Blackfan Anemia Patients

(2008) Hanna T. Gazda et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

Mycophenolic Acid Activation of p53 Requires Ribosomal Proteins L5 and L11

(2008) Xiao-Xin Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aberrant Expression of Nucleostemin Activates p53 and Induces Cell Cycle Arrest via Inhibition of MDM2

(2008) M.-S. Dai et al.   MOLECULAR AND CELLULAR BIOLOGY

Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26

(2008) Yaara Ofir-Rosenfeld et al.   MOLECULAR CELL

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

(2008) Benjamin L. Ebert et al.   NATURE