Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours

Truncation of the Catalytic Domain of the Cylindromatosis Tumor Suppressor Impairs Lung Maturation

(2015) Eirini Trompouki et al.   NEOPLASIA

Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action

(2010) Susanne C. Miller et al.   BIOCHEMICAL PHARMACOLOGY

Classical and/or alternative NF- B pathway activation in multiple myeloma

(2010) Y. N. Demchenko et al.   BLOOD

Lestaurtinib, a multitargeted tyrosinse kinase inhibitor: from bench to bedside

(2010) Munira Shabbir et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Loss of the Tumor Suppressor CYLD Enhances Wnt/β-Catenin Signaling through K63-Linked Ubiquitination of Dvl

(2010) Daniele V.F. Tauriello et al.   MOLECULAR CELL

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

(2010) N Turner et al.   ONCOGENE

Tumor Mapping in 2 Large Multigenerational Families With CYLD Mutations

(2009) Neil Rajan et al.   ARCHIVES OF DERMATOLOGY

Is overexpression of HER-2 a predictor of prognosis in colorectal cancer?

(2009) Dara O Kavanagh et al.   BMC CANCER

An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers

(2009) Rachael Natrajan et al.   BREAST CANCER RESEARCH AND TREATMENT

LEF-1 expression in basal cell carcinomas

(2009) L. Kriegl et al.   BRITISH JOURNAL OF DERMATOLOGY

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

(2009) Ji Luo et al.   CELL

Review of the Hair Follicle Origin Hypothesis for Basal Cell Carcinoma

(2009) Jeff Donovan   DERMATOLOGIC SURGERY

Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma

(2009) Ramin Massoumi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway

(2009) K. Thress et al.   MOLECULAR CANCER THERAPEUTICS

TrkA overexpression enhances growth and metastasis of breast cancer cells

(2009) C Lagadec et al.   ONCOGENE

Whole-Genome Gene Expression Profiling of Formalin-Fixed, Paraffin-Embedded Tissue Samples

(2009) Craig April et al.   PLoS One

p62 serves as a shuttling factor for TrkA interaction with the proteasome

(2008) Thangiah Geetha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Statistical issues in the analysis of Illumina data

(2008) Mark J Dunning et al.   BMC BIOINFORMATICS

Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia—A comparative study of four differently designed, high resolution microarray platforms

(2008) Rebeqa Gunnarsson et al.   GENES CHROMOSOMES & CANCER

Retracted: Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells

(2008) Nobuyuki Kikuno et al.   INTERNATIONAL JOURNAL OF CANCER

The Tumor Suppressor CYLD Regulates Microtubule Dynamics and Plays a Role in Cell Migration

(2008) Jinmin Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The genomic profile ofHER2-amplified breast cancers: the influence of ER status

(2008) C Marchiò et al.   JOURNAL OF PATHOLOGY

The Structure of the CYLD USP Domain Explains Its Specificity for Lys63-Linked Polyubiquitin and Reveals a B Box Module

(2008) David Komander et al.   MOLECULAR CELL

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/β-catenin signaling

(2008) Steven Hoseong Yang et al.   NATURE GENETICS