Dominant-negative mechanism of leukemogenic PAX5 fusions

Modeling the molecular consequences of unbalanced translocations in cancer: Lessons from acute lymphoblastic leukemia

(2011) Jonathan C. Strefford et al.   CELL CYCLE

PML-RARα/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia

(2010) Joost H.A. Martens et al.   CANCER CELL

Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations

(2010) Julianne Elvenes et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The reduced and altered activities of PAX5 are linked to the protein–protein interaction motif (coiled-coil domain) of the PAX5–PML fusion protein in t(9;15)-associated acute lymphocytic leukemia

(2010) J J Qiu et al.   ONCOGENE

PAX5/TEL Acts as a Transcriptional Repressor Causing Down-modulation of CD19, Enhances Migration to CXCL12, and Confers Survival Advantage in pre-BI Cells

(2008) G. Fazio et al.   CANCER RESEARCH

Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer

(2008) Q. An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray

(2008) N. Kawamata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coiled-coil domain of PML is essential for the aberrant dynamics of PML-RARα, resulting in sequestration and decreased mobility of SMRT

(2007) Ying Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS