Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial–mesenchymal transition and cancer stem cell properties

Homeoprotein Six1 Increases TGF-  Type I Receptor and Converts TGF-  Signaling from Suppressive to Supportive for Tumor Growth

(2010) D. S. Micalizzi et al.   CANCER RESEARCH

Molecular signaling of the epithelial to mesenchymal transition in generating and maintaining cancer stem cells

(2010) Gaoliang Ouyang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Human Telomerase RNA Gene Amplification Detection Increases the Specificity of Cervical Intraepithelial Neoplasia Screening

(2010) Lei Zheng et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

The Pathophysiology of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-β in Normal and Malignant Mammary Epithelial Cells

(2010) Molly A. Taylor et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

The Eyes Absent phosphatase-transactivator proteins promote proliferation, transformation, migration and invasion of tumor cells

(2010) R N Pandey et al.   ONCOGENE

Interactions with the Abelson Tyrosine Kinase Reveal Compartmentalization of Eyes Absent Function between Nucleus and Cytoplasm

(2009) Wenjun Xiong et al.   DEVELOPMENTAL CELL

Dephosphorylation of the C-terminal Tyrosyl Residue of the DNA Damage-related Histone H2A.X Is Mediated by the Protein Phosphatase Eyes Absent

(2009) Navasona Krishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical and Functional Characterization of SixSIX1Branchio-oto-renal Syndrome Mutations

(2009) Aaron N. Patrick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition

(2009) Erica L. McCoy et al.   JOURNAL OF CLINICAL INVESTIGATION

The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling

(2009) Douglas S. Micalizzi et al.   JOURNAL OF CLINICAL INVESTIGATION

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

(2009) Peter J. Cook et al.   NATURE

Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis

(2009) S J Miller et al.   ONCOGENE

SIX1mutation screening in 247 branchio-oto-renal syndrome families: a recurrent missense mutation associated with BOR

(2008) Amit Kochhar et al.   HUMAN MUTATION

Branchio-oto-renal syndrome (BOR): novel mutations in theEYA1gene, and a review of the mutational genetics of BOR

(2008) Dana J. Orten et al.   HUMAN MUTATION