Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential

(2010) Hiroyuki Oshiumi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The importance of steatosis in chronic hepatitis C infection and its management: A review

(2010) Timothy J. S. Cross et al.   HEPATOLOGY RESEARCH

Induction and Evasion of Innate Antiviral Responses by Hepatitis C Virus

(2010) Stanley M. Lemon   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Hepatitis C Virus Translation and Infectious Virus Production by the MicroRNA miR-122

(2010) R. K. Jangra et al.   JOURNAL OF VIROLOGY

DDX6 (Rck/p54) Is Required for Efficient Hepatitis C Virus Replication but Not for Internal Ribosome Entry Site-Directed Translation

(2010) R. K. Jangra et al.   JOURNAL OF VIROLOGY

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

(2010) S Whittaker et al.   ONCOGENE

Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection

(2010) K. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatocellular carcinoma in viral hepatitis: Improving standard therapy

(2009) Ryota Masuzaki et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

MiR-122/Cyclin G1 Interaction Modulates p53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells

(2009) F. Fornari et al.   CANCER RESEARCH

An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1  3' untranslated region confers risk for hepatocellular carcinoma

(2009) Y. Gao et al.   CARCINOGENESIS

Hepatitis C: recent successes and continuing challenges in the development of improved treatment modalities

(2009) Tetsuro Shimakami et al.   CURRENT OPINION IN PHARMACOLOGY

Visualizing Hepatitis C Virus Infections in Human Liver by Two-Photon Microscopy

(2009) Yuqiong Liang et al.   GASTROENTEROLOGY

Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression

(2009) Gary L. Davis et al.   GASTROENTEROLOGY

Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens

(2009) J G Fox et al.   GUT

Role of transforming growth factor β signaling and expansion of progenitor cells in regenerating liver

(2009) Arun Thenappan et al.   HEPATOLOGY

MicroRNA-122 Inhibits Tumorigenic Properties of Hepatocellular Carcinoma Cells and Sensitizes These Cells to Sorafenib

(2009) Shoumei Bai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatocellular Carcinoma Incidence, Mortality, and Survival Trends in the United States From 1975 to 2005

(2009) Sean F. Altekruse et al.   JOURNAL OF CLINICAL ONCOLOGY

Epidemiology of hepatocellular carcinoma in Japan

(2009) Takeji Umemura et al.   JOURNAL OF GASTROENTEROLOGY

Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein

(2009) A. G. N. Angus et al.   JOURNAL OF GENERAL VIROLOGY

Hepatitis C virus NS5A protein interacts with  -catenin and stimulates its transcriptional activity in a phosphoinositide-3 kinase-dependent fashion

(2009) A. Milward et al.   JOURNAL OF GENERAL VIROLOGY

Nonstructural 5A protein activates β-catenin signaling cascades: Implication of hepatitis C virus-induced liver pathogenesis

(2009) Chul-Yong Park et al.   JOURNAL OF HEPATOLOGY

Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice

(2009) Ai-Guo Wang et al.   JOURNAL OF PATHOLOGY

Impaired Replication of Hepatitis C Virus Containing Mutations in a Conserved NS5B Retinoblastoma Protein-Binding Motif

(2009) D. R. McGivern et al.   JOURNAL OF VIROLOGY

Toll-Like Receptor 3 Mediates Establishment of an Antiviral State against Hepatitis C Virus in Hepatoma Cells

(2009) N. Wang et al.   JOURNAL OF VIROLOGY

Modulation of Hepatitis C Virus RNA Abundance and the Isoprenoid Biosynthesis Pathway by MicroRNA miR-122 Involves Distinct Mechanisms

(2009) K. L. Norman et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus Causes Uncoupling of Mitotic Checkpoint and Chromosomal Polyploidy through the Rb Pathway

(2009) K. Machida et al.   JOURNAL OF VIROLOGY

The global burden of hepatitis C

(2009) Daniel Lavanchy   LIVER INTERNATIONAL

Hepatitis C-associated hepatocellular carcinomas in non-cirrhotic livers

(2009) Matthew M Yeh et al.   MODERN PATHOLOGY

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties

(2009) C Coulouarn et al.   ONCOGENE

Liver Cancer-Derived Hepatitis C Virus Core Proteins Shift TGF-Beta Responses from Tumor Suppression to Epithelial-Mesenchymal Transition

(2009) Serena Battaglia et al.   PLoS One

HCV Tumor Promoting Effect Is Dependent on Host Genetic Background

(2009) Naama Klopstock et al.   PLoS One

miR-221 overexpression contributes to liver tumorigenesis

(2009) P. Pineau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog

(2009) K. Machida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

Systematic identification of microRNA and messenger RNA profiles in hepatitis C virus-infected human hepatoma cells

(2009) Xiuying Liu et al.   VIROLOGY

Hepatocellular carcinoma in patients with autoimmune hepatitis

(2009) Andreas Teufel et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes

(2009) Kathie-Anne Walters et al.   PLoS Pathogens

HCV Induces Oxidative and ER Stress, and Sensitizes Infected Cells to Apoptosis in SCID/Alb-uPA Mice

(2009) Michael A. Joyce et al.   PLoS Pathogens

Position-Dependent Function for a Tandem MicroRNA miR-122-Binding Site Located in the Hepatitis C Virus RNA Genome

(2008) Catherine L. Jopling et al.   Cell Host & Microbe

microRNA-122 stimulates translation of hepatitis C virus RNA

(2008) Jura Inga Henke et al.   EMBO JOURNAL

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL

Incidence of Hepatocellular Carcinoma and Associated Risk Factors in Hepatitis C-Related Advanced Liver Disease

(2008) Anna S. Lok et al.   GASTROENTEROLOGY

Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: Implications for follow-up and screening

(2008) Andrew D. Yeoman et al.   HEPATOLOGY

Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells

(2008) Svetlana Marukian et al.   HEPATOLOGY

Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma

(2008) Shunsuke Ura et al.   HEPATOLOGY

The DNA Damage Sensors Ataxia-Telangiectasia Mutated Kinase and Checkpoint Kinase 2 Are Required for Hepatitis C Virus RNA Replication

(2008) Y. Ariumi et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus Infection Induces Apoptosis through a Bax-Triggered, Mitochondrion-Mediated, Caspase 3-Dependent Pathway

(2008) L. Deng et al.   JOURNAL OF VIROLOGY

p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines

(2008) M. Taura et al.   MOLECULAR AND CELLULAR BIOLOGY

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

(2008) Takeshi Saito et al.   NATURE

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Oncogenic role of DDX3 in breast cancer biogenesis

(2008) M Botlagunta et al.   ONCOGENE

NF-κB signaling, liver disease and hepatoprotective agents

(2008) B Sun et al.   ONCOGENE

Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death

(2008) Guaniri Mateu et al.   VIROLOGY

Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation

(2007) Chao-Kuen Lai et al.   VIROLOGY