Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability

Triple-negative breast cancers: Biomarkers and outcomes.

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Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells

(2011) Lori L. Sullivan et al.   CHROMOSOME RESEARCH

Cancer epigenetics reaches mainstream oncology

(2011) Manuel Rodríguez-Paredes et al.   NATURE MEDICINE

Centromeres: unique chromatin structures that drive chromosome segregation

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Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

(2011) D. T. Ting et al.   SCIENCE

The Histone Demethylase JMJD2B Is Regulated by Estrogen Receptor   and Hypoxia, and Is a Key Mediator of Estrogen Induced Growth

(2010) J. Yang et al.   CANCER RESEARCH

Mechanisms of Chromosomal Instability

(2010) Sarah L. Thompson et al.   CURRENT BIOLOGY

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore

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Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches

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A paucity of heterochromatin at functional human neocentromeres

(2010) Alicia Alonso et al.   Epigenetics & Chromatin

Hierarchical Inactivation of a Synthetic Human Kinetochore by a Chromatin Modifier

(2009) Stefano Cardinale et al.   MOLECULAR BIOLOGY OF THE CELL

SWI/SNF Deficiency Results in Aberrant Chromatin Organization, Mitotic Failure, and Diminished Proliferative Capacity

(2009) Ryan J. Bourgo et al.   MOLECULAR BIOLOGY OF THE CELL

CENPA overexpression promotes genome instability in pRb-depleted human cells

(2009) Angela Amato et al.   Molecular Cancer

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

(2009) G Liu et al.   ONCOGENE

Histone Modifications within the Human X Centromere Region

(2009) Brankica Mravinac et al.   PLoS One

Inactivation of a Human Kinetochore by Specific Targeting of Chromatin Modifiers

(2008) Megumi Nakano et al.   DEVELOPMENTAL CELL

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE

Interphase FISH Demonstrates that Human Adipose Stromal Cells Maintain a High Level of Genomic Stability in Long-Term Culture

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