Influence of stress on extracellular matrix and integrin biology

Gene Expression Profiles in 3D Tumor Analogs Indicate Compressive Strain Differentially Enhances Metastatic Potential

(2010) Zoe N. Demou   ANNALS OF BIOMEDICAL ENGINEERING

Cas-L was over-expressed in imatinib-resistant gastrointestinal stromal tumor cells

(2010) Le Ba Thao et al.   CANCER BIOLOGY & THERAPY

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

(2010) Isabelle Tanjoni et al.   CANCER BIOLOGY & THERAPY

Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models

(2010) Colin Walsh et al.   CANCER BIOLOGY & THERAPY

Human Enhancer of Filamentation 1 Is a Mediator of Hypoxia-Inducible Factor-1 -Mediated Migration in Colorectal Carcinoma Cells

(2010) S. H. Kim et al.   CANCER RESEARCH

The activities of MMP-9 and total gelatinase respond differently to substrate coating and cyclic mechanical stretching in fibroblasts and myoblasts

(2010) Ming C Cha et al.   CELL BIOLOGY INTERNATIONAL

Stretchy Proteins on Stretchy Substrates: The Important Elements of Integrin-Mediated Rigidity Sensing

(2010) Simon W. Moore et al.   DEVELOPMENTAL CELL

Role of hypoxia-induced fibronectin-integrin β1 expression in embryonic stem cell proliferation and migration: Involvement of PI3K/Akt and FAK

(2010) Sang Hun Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis

(2010) Anil K. Sood et al.   JOURNAL OF CLINICAL INVESTIGATION

A New α5β1 Integrin-Dependent Survival Pathway Through GSK3β Activation in Leukemic Cells

(2010) Fabienne De Toni-Costes et al.   PLoS One

Epidermal Growth Factor Receptor/ -Catenin/T-Cell Factor 4/Matrix Metalloproteinase 1: A New Pathway for Regulating Keratinocyte Invasiveness after UVA Irradiation

(2009) C. Jean et al.   CANCER RESEARCH

 v 3/ v 5 Integrins-FAK-RhoB: A Novel Pathway for Hypoxia Regulation in Glioblastoma

(2009) N. Skuli et al.   CANCER RESEARCH

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

HIF-1 is induced via EGFR activation and mediates resistance to anoikis-like cell death under lipid rafts/caveolae-disrupting stress

(2009) Seong-Hee Lee et al.   CARCINOGENESIS

Extracellular matrix genes as hypoxia-inducible targets

(2009) Johanna Myllyharju et al.   CELL AND TISSUE RESEARCH

Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2

(2009) Ju Han Song et al.   INTERNATIONAL JOURNAL OF CANCER

Antibodies blocking adhesion and matrix binding domains of laminin-332 inhibit tumor growth and metastasisin vivo

(2009) Sirpa Salo et al.   INTERNATIONAL JOURNAL OF CANCER

RGD-dependent integrins are mechanotransducers in dynamically compressed tissue-engineered cartilage constructs

(2009) Linda M. Kock et al.   JOURNAL OF BIOMECHANICS

LG4-5 domains of laminin-211 binds α-Dystroglycan to allow myotube attachment and prevent anoikis

(2009) Jesus Munoz et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

(2009) P P Provenzano et al.   ONCOGENE

Role of integrins and focal adhesion kinase in the orientation of dermal fibroblasts exposed to cyclic strain

(2009) Huang Wen et al.   International Wound Journal

Epidermal growth factor receptor is involved in enterocyte anoikis through the dismantling of E-cadherin-mediated junctions

(2008) Verónica-Haydée Lugo-Martínez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ultraviolet B and A irradiation induces fibromodulin expression in human fibroblasts in vitro

(2008) Barbara Iovine et al.   BIOCHIMIE

UV-C irradiation disrupts platelet surface disulfide bonds and activates the platelet integrin  IIb 3

(2008) R. Verhaar et al.   BLOOD

Hypoxia-Inducible Factor 1  Mediates Anoikis Resistance via Suppression of  5 Integrin

(2008) N. Rohwer et al.   CANCER RESEARCH

A Novel Association between p130Casand Resistance to the Chemotherapeutic Drug Adriamycin in Human Breast Cancer Cells

(2008) Huy Q. Ta et al.   CANCER RESEARCH

The Bone Marrow Microenvironment as a Tumor Sanctuary and Contributor to Drug Resistance

(2008) M. B. Meads et al.   CLINICAL CANCER RESEARCH

Cell adhesion receptors in mechanotransduction

(2008) Martin A Schwartz et al.   CURRENT OPINION IN CELL BIOLOGY

Selective induction of integrin β1 by hypoxia-inducible factor: implications for wound healing

(2008) Simon Keely et al.   FASEB JOURNAL

A celecoxib derivative inhibits focal adhesion signaling and induces caspase-8-dependent apoptosis in human acute myeloid leukemia cells

(2008) Isolda Casanova et al.   INTERNATIONAL JOURNAL OF CANCER

αvβ3 and αvβ5 integrins control glioma cell response to ionising radiation through ILK and RhoB

(2008) Sylvie Monferran et al.   INTERNATIONAL JOURNAL OF CANCER

From anchorage dependent proliferation to survival: Lessons from redox signalling

(2008) Paola Chiarugi   IUBMB LIFE

Increased expression of fibronectin and the α5β1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia

(2008) Richard Milner et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

3-D Tumor Model forIn VitroEvaluation of Anticancer Drugs

(2008) Jayme L. Horning et al.   MOLECULAR PHARMACEUTICS

Bortezomib overcomes cell adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma

(2008) K Hatano et al.   ONCOGENE

Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells

(2008) M A Westhoff et al.   ONCOGENE

Cell–Matrix Interactions Improve β-Cell Survival and Insulin Secretion in Three-Dimensional Culture

(2008) Laney M. Weber et al.   TISSUE ENGINEERING PART A