EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity

Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis

(2011) D Lu et al.   ONCOGENE

Dimethylcelecoxib inhibits mPGES-1 promoter activity by influencing EGR1 and NF-κB

(2010) Klaus Deckmann et al.   BIOCHEMICAL PHARMACOLOGY

Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages

(2010) Manuel D. Díaz-Muñoz et al.   CELLULAR SIGNALLING

New Strategies in Colorectal Cancer: Biomarkers of Response to Epidermal Growth Factor Receptor Monoclonal Antibodies and Potential Therapeutic Targets in Phosphoinositide 3-Kinase and Mitogen-Activated Protein Kinase Pathways

(2010) A. Dasari et al.   CLINICAL CANCER RESEARCH

Cyclooxygenase-2 and Cancer Treatment: Understanding the Risk Should Be Worth the Reward

(2010) D. G. Menter et al.   CLINICAL CANCER RESEARCH

Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis

(2009) Daisuke Kamei et al.   BIOCHEMICAL JOURNAL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Prostaglandin E 2 Primes the Angiogenic Switch via a Synergic Interaction With the Fibroblast Growth Factor-2 Pathway

(2009) Federica Finetti et al.   CIRCULATION RESEARCH

Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells

(2009) H. Hanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidermal growth factor increases prostaglandin E2 production via ERK1/2 MAPK and NF-κB pathway in fibroblast like synoviocytes from patients with rheumatoid arthritis

(2009) Seong-Su Nah et al.   RHEUMATOLOGY INTERNATIONAL

Genetic Deletion of mPGES-1 Suppresses Intestinal Tumorigenesis

(2008) M. Nakanishi et al.   CANCER RESEARCH

EGFR Antagonists in Cancer Treatment

(2008) Fortunato Ciardiello et al.   NEW ENGLAND JOURNAL OF MEDICINE