Structural Diversity Repertoire of Gene Silencing Small Interfering RNAs

Structural insights into RNA interference

(2010) Dipali G. Sashital et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Rational Design of Immunostimulatory siRNAs

(2010) Michael P Gantier et al.   MOLECULAR THERAPY

Multimeric small interfering ribonucleic acid for highly efficient sequence-specific gene silencing

(2010) Hyejung Mok et al.   NATURE MATERIALS

Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC

(2010) William Salomon et al.   NUCLEIC ACIDS RESEARCH

RNAi and small interfering RNAs in human disease therapeutic applications

(2010) Monica R. Lares et al.   TRENDS IN BIOTECHNOLOGY

RNAi-based therapeutics-current status, challenges and prospects

(2009) Katrin Tiemann et al.   EMBO Molecular Medicine

Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing

(2009) Seung-Young Lee et al.   JOURNAL OF CONTROLLED RELEASE

Asymmetric Shorter-duplex siRNA Structures Trigger Efficient Gene Silencing With Reduced Nonspecific Effects

(2009) Chan Il Chang et al.   MOLECULAR THERAPY

Dual-target gene silencing by using long, synthetic siRNA duplexes without triggering antiviral responses

(2009) Chan Il Chang et al.   MOLECULES AND CELLS

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

(2009) Yanli Wang et al.   NATURE

Erratum: Corrigendum: Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs

(2009) Aly A Khan et al.   NATURE BIOTECHNOLOGY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Structure of the guide-strand-containing argonaute silencing complex

(2008) Yanli Wang et al.   NATURE

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

(2008) Mark E. Kleinman et al.   NATURE

Asymmetric RNA duplexes mediate RNA interference in mammalian cells

(2008) Xiangao Sun et al.   NATURE BIOTECHNOLOGY

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

(2008) Hendrik Poeck et al.   NATURE MEDICINE

Forward and robust selection of the most potent and noncellular toxic siRNAs from RNAi libraries

(2008) Zhen Li et al.   NUCLEIC ACIDS RESEARCH

Effect of asymmetric terminal structures of short RNA duplexes on the RNA interference activity and strand selection

(2008) Masayuki Sano et al.   NUCLEIC ACIDS RESEARCH

Potent RNAi by short RNA triggers

(2008) C.-y. Chu et al.   RNA