Article
Public, Environmental & Occupational Health
Cheng Keat Tang, Lucia Macchia, Nattavudh Powdthavee
Summary: This article examines whether income inequality moderates the pain gap between the rich and the poor using data from over 1 million adults in 127 countries worldwide. The study finds that income is negatively associated with pain in most countries, but an increase in income is more effective in reducing pain in countries with relatively more equal income distribution. These results hold true even when using different measures of income inequality, removing outliers, and accounting for country and year fixed effects. The study suggests that pain-reducing policies through income redistribution should consider income inequality.
SOCIAL SCIENCE & MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Limor Man, Nicole Lustgarten Guahmich, Nina Vyas, Shelun Tsai, Laury Arazi, Debra Lilienthal, Glenn Schattman, Zev Rosenwaks, Daylon James
Summary: The ovarian reserve declines over time, leading to infertility, and it is important to understand the mechanisms behind ovarian reserve disorders for prevention and treatment. Primary prevention, by identifying toxic influences and preventing exposure, is the most desirable mode of fertility preservation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Public, Environmental & Occupational Health
Patrick Keating, Jillian Murray, Karl Schenkel, Laura Merson, Anna Seale
Summary: The study identified and described the use of electronic data tools for outbreak response in low- and middle-income countries. Multiple tools were found to be open source, capable of offline data collection and data visualisation. Key challenges included harmonisation of data tools and the need for preparedness through training front-line responders on data tools.
Review
Pediatrics
Maria Neocleous, Katelyn Hepworth, Vanessa Cavallera, Melissa Gladstone
Summary: This paper identifies 24 child development tools used in low/middle-income countries, with information on training accessibility and design found for 18 tools. Most training packages are proprietary and only available through face-to-face training, impacting their implementation and utilization in LMICs.
ARCHIVES OF DISEASE IN CHILDHOOD
(2023)
Article
Cell Biology
Harriet Evans, David Snead
Summary: AI-based diagnostic tools in histopathology offer advantages but are prone to errors. Pathologists should understand the limitations and play a role in minimizing errors.
Article
Green & Sustainable Science & Technology
Philipp A. Trotter, Imran Mannan, Aoife Brophy, Delight Sedzro, Abdulmutalib Yussuff, Francis Kemausuor, Yacob Mulugetta
Summary: The adoption of climate change mitigation policies does not necessarily lead to tangible change on the ground. For successful implementation, climate policies need to be integrated with economic and social development policies, leverage opportunities for green growth, build social capital, and establish cross-ministerial institutions to govern the process.
JOURNAL OF CLEANER PRODUCTION
(2022)
News Item
Multidisciplinary Sciences
Liam Drew
Summary: Researchers state that devices capable of recording and altering brain activity will present privacy concerns that question current human rights laws.
Article
Family Studies
Jorge Cuartas
Summary: Research has found that children exposed to corporal punishment are less likely to be developmentally on track compared to those who are not. The association between child development and corporal punishment may be driven by challenges in social-emotional development, and no positive developmental outcomes were associated with corporal punishment in any country.
CHILD ABUSE & NEGLECT
(2021)
Article
Information Science & Library Science
Chia-Ying Li, Yu-Hui Fang
Summary: This study examined transaction costs and their determinants in the sharing economy, using structural equation modeling to analyze data from 375 users of Airbnb. The findings suggest that personalization of asset specificity and transaction frequency decrease transaction costs, while learning of asset specificity and transaction uncertainty increase transaction costs, influencing behavioral intention. Perceived complementarity has a direct impact on transaction uncertainty, and the number of users moderates the relationship between transaction costs and behavioral intention. This understanding can guide managers in various industries impacted by the rapid growth of the sharing economy, providing them with strategies to address this trend.
INTERNATIONAL JOURNAL OF INFORMATION MANAGEMENT
(2022)
Review
Psychology, Multidisciplinary
Erika Branchini, Elena Capitani, Roberto Burro, Ugo Savardi, Ivana Bianchi
Summary: This paper highlights the importance of opposites as an organizing principle in human thinking, showing evidence from various studies that thinking in opposites can improve reasoning skills and problem-solving abilities. By prompting individuals to think in opposites, performance in tasks can be enhanced, leading to possible benefits that warrant further systematic testing and research.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Medicine, General & Internal
Agata Stanek, Giovanni Mosti, Temirov Surat Nematillaevich, Eva Maria Valesky, Tanja Planinsek Rucigaj, Malika Boucelma, George Marakomichelakis, Aaron Liew, Bahar Fazeli, Mariella Catalano, Malay Patel
Summary: Venous leg ulcers (VLUs) are serious complications of chronic venous insufficiency, with a high incidence and significant economic burden. To reduce the occurrence, it is important to identify high-risk patients at an early stage of chronic venous disease and implement preventive measures.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
R. J. Selvaratnam, D. L. Rolnik, M-A Davey, E. M. Wallace
Summary: The changing stillbirth risk profile of women has influenced the interpretation of stillbirth rate, with a faster decline in population rates of stillbirth due to changing maternal characteristics than previously estimated.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Tomi Akinyemiju, Kemi Ogunsina, Anjali Gupta, Iris Liu, Dejana Braithwaite, Robert A. Hiatt
Summary: Cancer burden is increasing globally, especially in low- and middle-income countries. These countries lack comprehensive cancer control programs and funding, therefore primary, secondary, and tertiary prevention strategies are needed to reduce the cancer burden.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Pengfei Li, Jingyi Wu, Ruohan Wang, Hengyi Liu, Tong Zhu, Tao Xue
Summary: This study analyzed the association between long-term exposure to PM2.5 from different sources and under-five deaths (U5Ds) in vulnerable children in low- and middle-income countries (LMICs). The results showed that PM2.5 from desert dust, solid biofuel combustion, and open fires had the greatest impact on child health. Public health interventions should consider the source profile of PM2.5 to effectively protect child health.
ENVIRONMENT INTERNATIONAL
(2023)
Review
Health Care Sciences & Services
Matthew Asare, Elakeche Abah, Dorcas Obiri-Yeboah, Lisa Lowenstein, Beth Lanning
Summary: This scoping review examines the application of HPV self-sampling among women with HIV in LMICs. The findings show a high participation rate and positive experience among women in self-sampling. However, there are personal, environmental, and structural barriers to the application of self-sampling in LMICs.
Article
Immunology
Nguyen Lam Vuong, Nguyen Than Ha Quyen, Nguyen Thi Hanh Tien, Nguyen Minh Tuan, Duong Thi Hue Kien, Phung Khanh Lam, Dong Thi Hoai Tam, Tran Van Ngoc, Sophie Yacoub, Thomas Jaenisch, Ronald B. Geskus, Cameron P. Simmons, Bridget A. Wills
Summary: Higher plasma viremia is associated with increased dengue severity, regardless of serotype or immune status, with effect sizes being modest compared to the effects of a secondary immune response. The association remains consistent across different age, serotype, and immune status groups, indicating a potential role of plasma viremia in predicting dengue severity.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Clinical Neurology
James Rush, Andrej Pal, Thomas Kapapa, Christian Rainer Wirtz, Benjamin Mayer, Annie Micah-Bonongwe, Melissa Gladstone, Patrick Kamalo
Summary: This study aimed to assess the neurodevelopmental outcomes of children with hydrocephalus in Malawi using locally appropriate tools. The results showed that a high proportion of these children experienced functional difficulties, stunted growth, and developmental delay.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2022)
Article
Medicine, General & Internal
Andrea M. Weckman, Andrea L. Conroy, Mwayiwawo Madanitsa, Bruno Gnaneswaran, Chloe R. Mcdonald, Linda Kalilani-Phiri, Jaya Chandna, Doreen Ali, Victor Mwapasa, Carole Khairallah, Kyaw Lay Thwai, Steven R. Meshnick, Steve M. Taylor, Feiko O. Ter Kuile, Kevin C. Kain, Melissa Gladstone
Summary: Exposure to malaria in pregnancy and maternal immune activation can lead to neurodevelopmental delays in children, particularly in language development. Successful interventions to prevent malaria during pregnancy may reduce the risk of neurocognitive delay in offspring.
Article
Clinical Neurology
Saraswathy Sabanathan, Omar Abdel-Mannan, Kshitij Mankad, Ata Siddiqui, Krishna Das, Lucinda Carr, Christin Eltze, Michael Eyre, Jon Gadian, Cheryl Hemingway, Marios Kaliakatsos, Rachel Kneen, Deepa Krishnakumar, Bryan Lynch, Amitav Parida, Thomas Rossor, Micheal Taylor, Evangeline Wassmer, Sukhvir Wright, Ming Lim, Yael Hacohen
Summary: This retrospective observational study investigated the clinical presentation, management, and disease course of pediatric autoimmune limbic encephalitis (LE). The findings suggest that a diagnosis of autoimmune LE is associated with significant morbidity and adverse outcomes in this pediatric cohort.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2022)
Review
Pediatrics
Maria Neocleous, Katelyn Hepworth, Vanessa Cavallera, Melissa Gladstone
Summary: This paper identifies 24 child development tools used in low/middle-income countries, with information on training accessibility and design found for 18 tools. Most training packages are proprietary and only available through face-to-face training, impacting their implementation and utilization in LMICs.
ARCHIVES OF DISEASE IN CHILDHOOD
(2023)
Article
Infectious Diseases
Savannah Karmen-Tuohy, Sebastian M. Mboma, John T. Langfitt, Rachel Brim, Melissa Gladstone, Terrie E. Taylor
Summary: This study reports on caregivers' perceptions and experiences of behaviour problems in children who survived cerebral malaria (CM) in Blantyre, Malawi. Behaviour problems reported include externalizing, aggressive behaviours, and learning difficulties. Caregiver experience is strongly impacted by family and community member responses. Future plans should focus on addressing these specific behaviour problems and providing education, rehabilitation, and support.
Article
Public, Environmental & Occupational Health
Bolajoko Olusanya, Nem Yun Boo, M. K. C. Nair, Maureen E. Samms-Vaughan, Mijna Hadders-Algra, Scott M. Wright, Cecilia Breinbauer, Nihad A. Almasri, Marisol Moreno-Angarita, Jalal Arabloo, Narendra K. Arora, Sandra S. Block, Brad D. Berman, Gwen Burchell, Olaf K. de Camargo, Gwen Carr, Christie del Castillo-Hegyi, Vivian G. Cheung, Ricardo Halpern, Rosa A. Hoekstra, Paul Lynch, Mphelekedzeni C. Mulaudzi, Angelina Kakooza-Mwesige, Felix A. Ogbo, Jacob O. Olusanya, Valeria Rojas-Osorio, Amira Shaheen, Andrew N. Williams, Chiara Servili, Melissa Gladstone, Hannah Kuper, Donald Wertlieb, Adrian C. Davis, Charles R. J. Newton
Summary: This paper highlights the urgent need to prioritize early childhood development for children with lifelong disabilities, particularly in low-income and middle-income countries as part of the Sustainable Development Goals agenda. Disability-focused programming, monitoring approaches, economic analysis of interventions, and substantial funding are required to address the current inequalities among this group of children by 2030.
LANCET GLOBAL HEALTH
(2022)
Article
Immunology
Marianne Koenraads, Todd D. Swarthout, Naor Bar-Zeev, Comfort Brown, Jacquline Msefula, Brigitte Denis, Queen Dube, Stephen B. Gordon, Robert S. Heyderman, Melissa J. Gladstone, Neil French
Summary: This study examined the burden of invasive pneumococcal disease (IPD) in infants <90 days old in Blantyre, Malawi over a 14-year period and evaluated the impact of the pneumococcal conjugate vaccine (PCV13) on vaccine-serotype IPD in this population. The results showed that vaccine serotypes 1 and 5 were the main cause of IPD in neonates and young infants, both before and after PCV13 introduction.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2022)
Review
Public, Environmental & Occupational Health
Amir Kirolos, Magdalena Goyheneix, Mike Kalmus Eliasz, Mphatso Chisala, Samantha Lissauer, Melissa Gladstone, Marko Kerac
Summary: Malnutrition in childhood has a significant negative impact on neurodevelopment, cognition, behavior, and mental health. Although there are limitations in the existing studies, the evidence strongly supports this association.
Article
Pediatrics
Sabahat Naz, Zahra Hoodbhoy, Ali Jaffar, Sidra Kaleem, Babar S. Hasan, Devyani Chowdhury, Melissa Gladstone
Summary: The study found that children born small for gestational age (SGA) may have poorer neurodevelopmental outcomes compared to those born appropriate for gestational age (AGA), particularly in the fine motor domain. Follow-up studies are needed to further assess the impact of SGA on the child's neurodevelopmental trajectory and school performance.
ARCHIVES OF DISEASE IN CHILDHOOD
(2023)
Review
Clinical Neurology
Saraswathy Sabanathan, Deepti Gulhane, Kshitij Mankad, James Davison, Min Tsui Ong, Rahul Phadke, Robert Robinson, Michael Spiller, Emma Wakeling, Sithara Ramdas, Angela F. Brady, Meena Balasubramanian, Pinki Munot
Summary: Individuals with biallelic TBCK pathogenic variants in infancy have distinct facial features, severe hypotonia, intellectual impairment, and epilepsy. The condition is rare and can be misdiagnosed as other neurogenetic disorders, leading to extensive investigations. Understanding the clinical phenotype helps in early monitoring of respiratory complications. We present six cases with pathogenic biallelic TBCK variants, highlighting the need for early respiratory surveillance in these individuals, especially those with periventricular leukomalacia-like changes.
NEUROMUSCULAR DISORDERS
(2023)
Article
Public, Environmental & Occupational Health
Bolajoko O. O. Olusanya, Melissa Gladstone, Scott M. M. Wright, Mijna Hadders-Algra, Nem-Yun Boo, M. K. C. Nair, Nihad Almasri, Vijaya Kancherla, Maureen E. E. Samms-Vaughan, Angelina Kakooza-Mwesige, Tracey Smythe, Christie del Castillo-Hegyi, Ricardo Halpern, Olaf K. K. de Camargo, Jalal Arabloo, Aziz Eftekhari, Amira Shaheen, Sheffali Gulati, Andrew N. N. Williams, Jacob O. O. Olusanya, Donald Wertlieb, Charles R. J. Newton, Adrian C. C. Davis
Summary: Children with developmental disabilities are at high risk of poor school enrollment and educational attainment without timely and appropriate support. This paper provides evidence on the global and regional prevalence of cerebral palsy (CP) and developmental intellectual disability among children under 5 years old in 2019. The study shows that CP and intellectual disability are highly prevalent worldwide and are associated with significant years lived with disability among children under 5 years.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Vanessa Cavallera, Gillian Lancaster, Melissa Gladstone, Maureen M. Black, Gareth McCray, Ambreen Nizar, Salahuddin Ahmed, Arup Dutta, Romuald Kouadio E. Anago, Alexandra Brentani, Fan Jiang, Yvonne Schoenbeck, Dana C. McCoy, Patricia Kariger, Ann M. Weber, Abbie Raikes, Marcus Waldman, Stef van Buuren, Raghbir Kaur, Michelle Perez Maillard, Muhammad Imran Nisar, Rasheda Khanam, Sunil Sazawal, Arsene Zongo, Mariana Pacifico Mercadante, Yunting Zhang, Arunangshu D. Roy, Katelyn Hepworth, Guenther Fink, Marta Rubio-Codina, Fahmida Tofail, Iris Eekhout, Jonathan Seiden, Rebecca Norton, Abdullah H. Baqui, Jamila Khalfan Ali, Jin Zhao, Andreas Holzinger, Symone Detmar, Samuel Nzale Kembou, Farzana Begum, Said Mohammed Ali, Fyezah Jehan, Tarun Dua, Magdalena Janus
Summary: The aim of this study is to validate the Global Scales for Early Development (GSED) and create reference scores for its short form and long form. The study will be conducted in seven countries with a total of 1248 children, using cross-sectional and longitudinal methods. The findings will be disseminated through various channels.
Article
Psychology, Developmental
Alice Fortune, Elizabeth Perkins, Fauzia Paize, Balamurugan Palanisami, Melissa Gladstone
Summary: This study explores parents' perspectives and experiences in early neurodevelopmental follow-up of at-risk infants. The research findings indicate that parents require appropriate information and support to manage uncertainty. Adequate preparation and timing of information, as well as tailored information based on individual needs, are crucial in this context.
CHILD CARE HEALTH AND DEVELOPMENT
(2023)
Meeting Abstract
Health Care Sciences & Services
Gareth McCray, Melissa Gladstone, Vanessa Cavallera, Dana Mccoy, Marcus Waldman, Iris Eekhout, Stef van Buuren, Mag-Dalena Janus, Patricia Kariger, Maureen Black, Ann Weber
QUALITY OF LIFE RESEARCH
(2022)
