4.2 Article

The effect of pulpotomy using a Calcium-Enriched Mixture cement versus one-visit root canal therapy on postoperative pain relief in irreversible pulpitis: a randomized clinical trial

Journal

ODONTOLOGY
Volume 98, Issue 2, Pages 126-133

Publisher

SPRINGER
DOI: 10.1007/s10266-010-0127-2

Keywords

CEM cement; NEC; Pain; Pulpitis; Pulpotomy

Funding

  1. Iranian Ministry of Health and Medical Education (Health Deputy, Oral Health Office)
  2. Iranian Center for Endodontic Research, Shahid Beheshti Medical University, Tehran, Iran
  3. Ministry of Health and Medical Education Tehran, Iran

Ask authors/readers for more resources

The purpose of this noninferiority trial was to compare postoperative pain relief after one-visit root canal therapy (ORCT) with a pulpotomy performed with a new endodontic calcium-enriched mixture cement (PCEM) in human permanent molars with irreversible pulpitis. A total of 407 selected patients were randomly allocated into the ORCT group (n = 202) or the PCEM group (n = 205). Numerical Rating Scale questionnaires were used to record pain intensity (PI) by the patients during the first 7 days after treatment. While there was no statistically significant difference in the mean PI at baseline between the two study groups (P = 0.45), changes in mean PI were significantly different between them (P < 0.001). In the ORCT group, pain relief was achieved after 36 h [95% confidence interval (CI), 27.00-45.00], compared to 18 h in the PCEM group (95% CI, 15.00-21.00), a significant difference (P < 0.01). Comparison of the mean PI sum recorded over 7 days showed that patients in the ORCT group experienced significantly more pain than those in the PCEM group (P < 0.001); a similar difference was observed for pain in response to percussion tests (P < 0.001). Treatment with PCEM thus had the better pain-reducing effects than ORCT in irreversible pulpitis cases.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Review Dentistry, Oral Surgery & Medicine

Effects of antibiotic administration on post-operative endodontic symptoms in patients with pulpal necrosis: A systematic review and meta-analysis

Sayna Shamszadeh, Saeed Asgary, Armin Shirvani, Mohammad Jafar Eghbal

Summary: The administration of prophylactic antibiotics to prevent post-operative endodontic symptoms is not supported by the current evidence.

JOURNAL OF ORAL REHABILITATION (2021)

Article Dentistry, Oral Surgery & Medicine

Outcomes of root canal therapy or full pulpotomy using two endodontic biomaterials in mature permanent teeth: a randomized controlled trial

Saeed Asgary, Mohammad Jafar Eghbal, Arash Shahravan, Eshaghali Saberi, Alireza Akbarzadeh Baghban, Ardavan Parhizkar

Summary: In mature permanent teeth, both full pulpotomy using mineral trioxide aggregate and calcium-enriched mixture cement, as well as root canal therapy showed comparable clinical and radiographic results at the two-year follow-up.

CLINICAL ORAL INVESTIGATIONS (2022)

Letter Dentistry, Oral Surgery & Medicine

Management of an unrepairable root perforation due to inflammatory root resorption: A case report

S. Asgary

JOURNAL OF DENTAL SCIENCES (2022)

Article Medicine, General & Internal

Health system performance in Iran: a systematic analysis for the Global Burden of Disease Study 2019

Farshad Farzadfar, Mohsen Naghavi, Sadaf G. Sepanlou, Sahar Saeedi Moghaddam, William James Dangel, Nicole Davis Weaver, Arya Aminorroaya, Sina Azadnajafabad, Sogol Koolaji, Esmaeil Mohammadi, Negar Rezaei, Jaffar Abbas, Behzad Abbasi, Mitra Abbasifard, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Hedayat Abbastabar, Amir Abdoli, Mohammad Abdollahi, Sina Abdollahzade, Hassan Abolhassani, Zahra Abrehdari-Tafreshi, Soodabeh Aghababaei, Bahman Ahadinezhad, Ali Ahmadi, Sepideh Ahmadi, Hamid Ahmadieh, Mohammad Esmaeil Akbari, Yousef Alimohamadi, Vahid Alipour, Hesam Alizade, Saba Alvand, Saeed Amini, Sohrab Amiri, Ali Arash Anoushirvani, Fereshteh Ansari, Jalal Arabloo, Morteza Arab-Zozani, Zahra Aryan, Armin Aryannejad, Mehran Asadi-Aliabadi, Ali A. Asadi-Pooya, Zatollah Asemi, Samaneh Asgari, Saeed Asgary, Babak Asghari, Mohammad Asghari Jafarabadi, Elham Ashrafi, Zahra Atafar, Seyyed Shamsadin Athari, Abolfazl Avan, Abbas Azadmehr, Hiva Azami, Mohammadreza Azangou-Khyavy, Samad Azari, Amirhossein Azari Jafari, Ghasem Azarian, Alireza Badirzadeh, Elham Bahrami, Mohammad Amin Bahrami, Nastaran Barati, Mohsen Bayati, Gholamreza Bazmandegan, Masoud Behzadifar, Ali Bijani, Somayeh Bohlouli, Shiva Borzouei, Parnaz Daneshpajouhnejad, Abdollah Dargahi, Ahmad Daryani, Jalal Davoodi Lahijan, Mojtaba Didehdar, Shirin Djalalinia, Saeid Doaei, Fariba Dorostkar, Leila Doshmangir, Mohammadreza Edraki, Amir Emami, Babak Eshrati, Sharareh Eskandarieh, Firooz Esmaeilzadeh, Shahriar Faghani, Mahdi Fakhar, Hamid Reza Farpour, Hossein Farrokhpour, Majid Fasihi Harandi, Mohammad Fereidouni, Masoud Foroutan, Mansour Ghafourifard, Azin Ghamari, Seyyed-Hadi Ghamari, Ahmad Ghashghaee, Fariba Ghassemi, Ali Gholami, Asadollah Gholamian, Abdolmajid Gholizadeh, Salime Goharinezhad, Pouya Goleij, Mostafa Hadei, Nima Hafezi-Nejad, Sanam Hariri, Edris Hasanpoor, Hossein Hassanian-Moghaddam, Soheil Hassanipour, Hadi Hassankhani, Mohammad Heidari, Reza Heidari-Soureshjani, Mohammad Hoseini, Mohammad-Salar Hosseini, Mostafa Hosseini, Seyed Kianoosh Hosseini, Ali Hosseinzadeh, Mehdi Hosseinzadeh, Soodabeh Hoveidamanesh, Pooya Iranpour, Seyed Sina Naghibi Irvani, Jalil Jaafari, Roxana Jabbarinejad, Morteza Jafarinia, Hamed Jafari-Vayghan, Mohammad Ali Jahani, Nader Jahanmehr, Mahsa Jalili, Roksana Janghorban, Fatemeh Javanmardi, Farahnaz Joukar, Ali Kabir, Leila R. Kalankesh, Rohollah Kalhor, Zahra Kamiab, Naser Kamyari, Behzad Karami Matin, Amirali Karimi, Salah Eddin Karimi, Ali Kazemi Karyani, Leila Keikavoosi-Arani, Maryam Keramati, Pedram Keshavarz, Mohammad Keykhaei, Ali Khaleghi, Mohammad Khammarnia, Javad Khanali, Maryam Khayamzadeh, Sajad Khosravi, Mina Khosravifar, Omid Khosravizadeh, Neda Kianipour, Ali-Asghar Kolahi, Amirhosein Maali, Mokhtar Mahdavi, Afshin Maleki, Mohammad-Reza Malekpour, Kamyar Mansori, Borhan Mansouri, Mohammad Ali Mansournia, Mohammad Reza Maracy, Abdoljalal Marjani, Sahar Masoudi, Seyedeh Zahra Masoumi, Hossein Masoumi-Asl, Mahsa Mayeli, Entezar Mehrabi Nasab, Fereshteh Mehri, Mohammad Miri, Seyyedmohammadsadeq Mirmoeeni, Hamed Mirzaei, Maryam Mirzaei, Roya Mirzaei, Ashraf Mohamadkhani, Heidar Mohammadi, Seyyede Momeneh Mohammadi, Shadieh Mohammadi, Abdollah Mohammadian-Hafshejani, Noushin Mohammadifard, Reza Mohammadpourhodki, Mohammad Mohseni, Amin Mokari, Sara Momtazmanesh, Abdolvahab Moradi, Masoud Moradi, Yousef Moradi, Mohammad Moradi-Joo, Farhad Moradpour, Maliheh Moradzadeh, Rahmatollah Moradzadeh, Abbas Mosapour, Shandiz Moslehi, Simin Mouodi, Mehdi Naderi, Homa Naderifar, Zhila Najafpour, Javad Nazari, Seyed Aria Nejadghaderi, Leila Nemati-Anaraki, Amin Reza Nikpoor, Marzieh Nojomi, Maryam Noori, Hasti Nouraei, Ali Nowroozi, Morteza Oladnabi, Fatemeh Pashazadeh Kan, Majid Pirestani, Meghdad Pirsaheb, Mohammadreza Pourahmadi, Hadis Pourchamani, Hadi Pourjafar, Akram Pourshams, Mohammad Rabiee, Navid Rabiee, Alireza Rafiei, Sima Rafiei, Fakher Rahim, Amir Masoud Rahmani, Sina Rashedi, Vahid Rashedi, Amirfarzan Rashidi, Mahsa Rashidi, Mohammad-Mahdi Rashidi, Ramin Ravangard, Reza Rawassizadeh, Iman Razeghian-Jahromi, Mohammad Sadegh Razeghinia, Sofia B. Redford, Maryam Rezaei, Nazila Rezaei, Nima Rezaei, Saeid Rezaei, Hossein Rezaei Aliabadi, Mohsen Rezaeian, Mohammad Sadegh Rezai, Aziz Rezapour, Hossein Rezazadeh, Sahba Rezazadeh-Khadem, Morteza Rostamian, Ehsan Sadeghi, Erfan Sadeghi, Masoumeh Sadeghi, Reihaneh Sadeghian, Saeid Sadeghian, Hamid Safarpour, Mahdi Safdarian, Sare Safi, Maryam Sahebazzamani, Amirhossein Sahebkar, Mohammad Ali Sahraian, Sarvenaz Salahi, Payman Salamati, Hossein Samadi Kafil, Yaser Sarikhani, Maryam Sarkhosh, Arash Sarveazad, Maryam Seyed-Nezhad, Omid Shafaat, Zahra Shaghaghi, Saeed Shahabi, Sarvenaz Shahin, Elaheh Shaker, Saeed Shakiba, MohammadBagher Shamsi, Erfan Shamsoddin, Kiomars Sharafi, Sakineh Sharifian, Maryam Shaygan, Abbas Sheikhtaheri, Amir Shiani, Kiarash Shirbandi, Reza Shirkoohi, Parnian Shobeiri, Azad Shokri, Soraya Siabani, Ali Reza Sima, Ahmad Sofi-Mahmudi, Amin Soheili, Shahin Soltani, Mohammad Sadegh Soltani-Zangbar, Moslem Soofi, Seidamir Pasha Tabaeian, Mohammadreza Tabary, Alireza Tahamtan, Majid Taheri, Amir Taherkhani, Masih Tajdini, Hamed Tavolinejad, Arash Tehrani-Banihashemi, Amir Tiyuri, Seyed Abolfazl Tohidast, Alireza Vakilian, Sahel Valadan Tahbaz, Bay Vo, Seyed Hossein Yahyazadeh Jabbari, Vahid Yazdi-Feyzabadi, Zabihollah Yousefi, Taraneh Yousefinezhadi, Mazyar Zahir, Telma Zahirian Moghadam, Maryam Zamanian, Hamed Zandian, Alireza Zangeneh, Hadi Zarafshan, Fariba Zare, Ali Zare Dehnavi, Kourosh Zarea, Ahmad Zarei, Zahra Zareshahrabadi, Arash Ziapour, Sina Zoghi, Nizal Sarrafzadegan, Vafa Rahimi-Movaghar, Hamid Reza Jamshidi, Ali H. Mokdad, Simon Hay, Christopher J. L. Murray, Ardeshir Khosravi, Maziar Moradi-Lakeh, Mohsen Asadi-Lari, Reza Malekzadeh, Bagher Larijani

Summary: Iran's healthcare system is facing the challenge of non-communicable diseases and requires a coordinated multisectoral approach. While it has been successful in controlling mortality, it has overlooked the burden of morbidity and the need for rehabilitation.

LANCET (2022)

Letter Dentistry, Oral Surgery & Medicine

A successful pulpotomy-treated permanent molar withstood recurrent decay after 10 years of treatment

Saeed Asgary

JOURNAL OF DENTAL SCIENCES (2022)

Letter Dentistry, Oral Surgery & Medicine

Surgical management of large-perforated class 4 invasive cervical root resorption: A case report

Saeed Asgary

JOURNAL OF DENTAL SCIENCES (2023)

Article Dentistry, Oral Surgery & Medicine

Management of External Inflammatory Root Resorption following Tooth Autotransplantation Using a Modified Combination of Triple Antibiotics

Saeed Asgary, Ardavan Parhizkar

Summary: External inflammatory root resorption (EIRR) is a detrimental consequence of tooth trauma. This study demonstrates an effective method to prevent and control EIRR, through thorough preparation of root canals and the application of a triple antibiotic combination. The use of calcium-enriched mixture cement and proper management of EIRR resulted in the healing of the tooth.

CASE REPORTS IN DENTISTRY (2022)

Letter Dentistry, Oral Surgery & Medicine

Simple re-attachment of a complete crown fracture to avoid complex replacement: A case report

Saeed Asgary, Ardavan Parhizkar

JOURNAL OF DENTAL SCIENCES (2023)

Letter Dentistry, Oral Surgery & Medicine

Healing of a large endodontic lesion due to a procedural accident using intentional replantation; a case report

Saeed Asgary, Ardavan Parhizkar

JOURNAL OF DENTAL SCIENCES (2023)

Article Dentistry, Oral Surgery & Medicine

Healing of Large Endodontic Lesions Using Long-Term Application of a New Combination of Triple Antibiotics: A Series of Cases

Saeed Asgary, Ardavan Parhizkar

Summary: Apical periodontitis (AP) is an inflammatory reaction due to bacterial invasion of dental pulp and root canal system, leading to tissue destruction. Non-surgical approaches with a modified combination of antibiotics (Penicillin G, metronidazole, and ciprofloxacin) were used in endodontic retreatments for large AP. Follow-up showed complete recovery and bone healing, indicating the successful resolution of large AP. Further research and controlled clinical trials are recommended.

CASE REPORTS IN DENTISTRY (2023)

Letter Dentistry, Oral Surgery & Medicine

Emphasizing the impact of artificial intelligence in dentistry: A call for integration and exploration

Saeed Asgary

JOURNAL OF DENTAL SCIENCES (2023)

Review Radiology, Nuclear Medicine & Medical Imaging

A Bibliometric Study on the Top 101 Most-Cited Articles of Dental Journals of the Middle East/North Africa Countries From 2011 to 2021

Leyla Roghanizadeh, Alireza Akbarzadeh Baghban, Jila Azizzadeh, Saeed Asgary

Summary: This retrospective descriptive study evaluated the Scopus-indexed dental journals and their most-cited documents affiliated with the Middle East and North Africa (MENA) countries from 2011 to 2021. The study extracted and analyzed dental journals affiliated with MENA countries, their bibliometric indicators, and the 101 most cited articles. The European Journal of Dentistry from Turkey, Saudi Dental Journal from Saudi Arabia, and Iranian Endodontic Journal and Journal of Lasers in Medical Sciences from Iran were found to have the highest ranks and scores in bibliometric indices among MENA dental journals.

JOURNAL OF LASERS IN MEDICAL SCIENCES (2023)

Article Dentistry, Oral Surgery & Medicine

Cytokine co-stimulation effect on odontogenic differentiation of stem cells

Sayna Shamszadeh, Saeed Asgary, Hassan Torabzadeh, Simzar Hosseinzadeh, Ali Nosrat

Summary: This study evaluated the effect of co-stimulation with bone morphogenetic protein-2 (BMP-2) and transforming growth factor-beta 1 (TGF-beta 1) on the odontogenic differentiation of human dental pulp stem cells (hDPSCs). The results showed that BMP-2 was essential for odontogenic differentiation, and co-stimulation with TGF-beta 1 enhanced this process. Continuous stimulation with TGF-beta 1 did not improve the differentiation of hDPSCs.

CLINICAL ORAL INVESTIGATIONS (2022)

Article Dentistry, Oral Surgery & Medicine

Grafting with Bone Substitute Materials in Therapy-Resistan Periapical Actinomycosis

Saeed Asgary, Leyla Roghanizadeh

Summary: Actinomycosis can lead to difficult-to-treat lesions. Surgical endodontic retreatment coupled with bone filling can aid in bone healing. The use of CEM cement and bone substitutes may be effective in treating large periradicular lesions caused by apical actinomycosis.

CASE REPORTS IN DENTISTRY (2021)

No Data Available