Article
Environmental Sciences
Marine Lemaitre, Pauline Frenoy, Thibault Fiolet, Caroline Besson, Francesca Romana Mancini
Summary: This study analyzed the relationship between dietary exposure to DL and NDL PCB and NHL risk, finding a positive association between DL PCB and Diffuse Large B Cell Lymphoma, and a negative association between NDL PCB and follicular lymphoma. However, these associations were no longer significant when fish and dairy product consumption was adjusted for.
ENVIRONMENTAL RESEARCH
(2021)
Article
Multidisciplinary Sciences
Mario Bunse, Janina Pfeilschifter, Julia Bluhm, Maria Zschummel, Jara J. Joedicke, Anthea Wirges, Helen Stark, Vivien Kretschmer, Markus Chmielewski, Wolfgang Uckert, Hinrich Abken, Joerg Westermann, Armin Rehm, Uta E. Hoepken
Summary: The study demonstrates that CAR-T cells targeting CXCR5 effectively inhibit tumor growth by depleting both B cells and follicular T helper cells in lymphoma models, suggesting a promising treatment strategy for nodal B-NHLs.
NATURE COMMUNICATIONS
(2021)
Article
Immunology
Kissy Guevara-Hoyer, Jesus Fuentes-Antras, Eduardo de la Fuente-munoz, Miguel Fernandez-Arquero, Fernando Solano, Pedro Perez-Segura, Esmeralda Neves, Alberto Ocana, Rebeca Perez de Diego, Silvia Sanchez-Ramon
Summary: This study aims to explore the shared genomic basis between common variable immunodeficiency (CVID) and non-Hodgkin's lymphoma (NHL), in order to better understand the immunodeficiency phenotype of CVID in NHL. The study found that NHL samples harbored genetic variants associated with CVID, indicating the existence of shared pathological mechanisms and signaling pathways.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Maria Kallergi, Alexandros Georgakopoulos, Vassiliki Lyra, Sofia Chatziioannou
Summary: This study investigated the value of tumor measurements in predicting treatment outcomes for Hodgkin's and Non-Hodgkin's lymphomas. Results showed that while SUVmax was the strongest prognostic indicator, automated metabolic tumor volume measurements and expert's metabolic maximum diameter measurements also provided valuable insights. Anatomic tumor measurements had poor prognostic value. The study suggests a paradigm shift towards identifying robust prognostic markers in PET/CT with the use of radiomics.
Article
Multidisciplinary Sciences
De Matteis Sara, Cosetta Minelli, Giorgio Broccia, Paolo Vineis, Pierluigi Cocco
Summary: This ecological study investigates the link between COVID-19 incidence, socio-economic covariates, and NHL incidence. The results show that COVID-19 cumulative incidence is positively associated with past NHL incidence, socioeconomic deprivation, and proportion of elderly residents, while negatively associated with urban residency. Further investigation is needed to explore shared susceptibility factors among the plausible underlying mechanisms.
Article
Medicine, General & Internal
Jiamei Wu, Yin Zhou, Qingshu Li, Jing Zhang, Yun Mao
Summary: PBNHL is a rare disease with difficult preoperative diagnosis, so it should be considered when encountering cases with Epstein-Barr virus infection and typical imaging findings.
Article
Environmental Sciences
Elizabeth Gaspard, Pauline Frenoy, Delphine Praud, Thomas Coudon, Leny Grassot, Aline Abou Assi, Beatrice Fervers, Amandine Gelot, Francesca Romana Mancini, Gianluca Severi, Caroline Besson, Elodie Faure
Summary: This study found a significant positive correlation between cumulative airborne dioxin exposure and the risk of NHL in women, particularly with the CLL and SLL subtypes.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Multidisciplinary Sciences
Giorgio Broccia, Jonathan Carter, Cansu Ozsin-Ozler, Federico Meloni, Sara De Matteis, Pierluigi Cocco
Summary: The incidence of non-Hodgkin's lymphoma (NHL) in Sardinia showed an upward trend from 1974 to 2003, prompting further research on the genetic and environmental factors in the high-risk areas.
Article
Oncology
Richard A. Newcomb, P. Connor Johnson, Daniel Yang, Katherine Holmbeck, Joanna Choe, Anisa Nabily, Porsha Lark, Tejaswini Dhawale, Hermioni L. Amonoo, Areej El-Jawahri
Summary: Patients with indolent non-Hodgkin's lymphomas (iNHL) report significant psychological distress, a diversity of coping strategies, and complex cognitive understanding of their prognosis. Interventions that address prognostic uncertainty and promote positive emotional coping with prognosis may ameliorate psychological distress in this population.
Article
Oncology
Weifeng Wang, Zhuo Zhang, Xiaocong Deng, Anqi Gu, Xianzhao Chen, Yizheng Cai, Yuting Zhao
Summary: In this case report, a 57-year-old male patient with diffuse large B-cell lymphoma was successfully treated with radiation therapy and medication, achieving complete remission.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Louis-Marie Garcin, Amandine Gelot, Roselyn-Rima Gomez, Gaelle Gusto, Marie-Christine Boutron-Ruault, Marina Kvaskoff, Gianluca Severi, Caroline Besson
Summary: The study findings suggest that certain pigmentary traits, such as the presence of nevi and skin sensitivity, rather than sun exposure, are associated with the risk of chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphomas (NHL).
Article
Oncology
Kathryn Lurain, Ramya Ramaswami, Ralph Mangusan, Anaida Widell, Irene Ekwede, Jomy George, Richard Ambinder, Martin Cheever, James L. Gulley, Priscila H. Goncalves, Hao-Wei Wang, Thomas S. Uldrick, Robert Yarchoan
Summary: The most common malignancy among people living with HIV in the USA is Non-Hodgkin's lymphoma (NHL). The study found that using pembrolizumab with or without pomalidomide to treat HIV-associated NHL elicited responses in several subtypes of HIV-associated NHL. This approach is worth further study in individuals living with HIV and NHL.
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
Review
Oncology
Lara Mussolin, Christine Damm-Welk, Marta Pillon, Wilhelm Woessmann
Summary: The detection of minimal residual disease (MRD) is crucial for relapse risk assessment in leukemia and treatment optimization in adult lymphomas. However, the application of MRD studies in childhood non-Hodgkin lymphomas is complex due to various challenges such as stratified treatment, high cure rates, limited patient numbers, and different clinical applications based on subtypes. Validation of MRD as prognostic parameters in childhood lymphomas is necessary, with next-generation sequencing-based methods offering new possibilities.
Review
Oncology
Min Zhu, Zhixuan Wu, Zhaoxia Yang, Bo Ning, Shengjie Yu, Xiling Gu, Huihong Yu
Summary: Peritoneal lymphomatosis is a rare disease with poor prognosis that can be easily neglected and misdiagnosed. Early pathological diagnosis is crucial for initiating the correct treatment, and the discovery of lymphomatosis in the peritoneum is a rare finding.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Jingwen Li, Fei Peng, He Huang, Zhen Cai
Summary: The relative and cumulative risk of developing second primary malignancies significantly increased in patients diagnosed with non-Hodgkin's lymphoma in recent years. The risk was associated with certain clinical and demographic variables.
AMERICAN JOURNAL OF CANCER RESEARCH
(2022)
