Article
Endocrinology & Metabolism
Tingting Lei, Ting Qiu, Wanyu Liao, Kangjie Li, Xinyue Lai, Hongbo Huang, Rui Yuan, Ling Chen
Summary: This study found that the severity of 24-hour proteinuria may be related to adverse pregnancy outcomes in women with preeclampsia, especially in terms of the rates of induced labor and stillbirth.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2021)
Article
Genetics & Heredity
Handong Sun, Zijuan Wu, Ming Liu, Liang Yu, Jianyong Li, Jinwen Zhang, Xiangming Ding, Hui Jin
Summary: Circular RNA (circRNA) is a novel regulatory non-coding RNA that participates in various physiological and pathological processes. The study found internal complementary base-pairing sequences (ICBPS) in many circRNAs, especially in extremely long circRNAs, suggesting that circRNAs may not have a simple circular structure. The hypothesis of open-close effect in the transition of circRNA from normal state to morbid state was proposed, expanding the understanding of circRNAs and highlighting their potential molecular mechanisms.
FRONTIERS IN GENETICS
(2021)
Article
Medicine, General & Internal
Qian Yang, Maria C. Magnus, Fanny Kilpi, Gillian Santorelli, Ana Goncalves Soares, Jane West, Per Magnus, John Wright, Siri Eldevik Haberg, Eleanor Sanderson, Deborah A. Lawlor, Kate Tilling, Maria Carolina Borges
Summary: Observational studies have shown that maternal sleep duration is associated with adverse pregnancy and perinatal outcomes. However, it is unclear whether there are nonlinear causal effects. This study used Mendelian randomization and multivariable regression to examine the nonlinear effects of sleep duration on various outcomes. The results suggest that shorter and longer sleep duration may increase the risks of stillbirth, perinatal depression, and low offspring birthweight.
Article
Medicine, Research & Experimental
Ying Xing, Lina Wen, Jia Zhang, Haiyan Li, Jing Ma
Summary: Adverse pregnancy outcomes are a devastating reality in clinics, with factors such as lupus anticoagulant positivity and angiogenic markers being correlated with poor pregnancy outcomes and neonatal health.
CLINICAL AND EXPERIMENTAL MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Maria Lantzanaki, Theofanis Vavilis, Vikentia C. Harizopoulou, Helen Bili, Dimitrios G. Goulis, Dimitrios Vavilis
Summary: This review presents the role of ceramides during pregnancy and obstetrical adverse outcomes, as well as their potential as biomarkers in such conditions.
Article
Clinical Neurology
Eliza Miller, Anni E. Kauko, Sarah Tom, Hannele Laivuori, Teemu A. Niiranen, Natalie Bello
Summary: The study found that adverse pregnancy outcomes are associated with an earlier onset of maternal cerebrovascular disease, especially in cases where women had more than one affected pregnancy.
Review
Endocrinology & Metabolism
Claudia Main, Xinyue Chen, Min Zhao, Lawrence W. Chamley, Qi Chen
Summary: Multiparous women have a lower risk of developing ovarian and endometrial cancer, which has traditionally been attributed to the decrease in estrogen levels and increase in progesterone levels during pregnancy. However, recent evidence suggests that nonendocrine mechanisms may also play a role.
Review
Clinical Neurology
Qingdong Lu, Xiaoyan Zhang, Yunhe Wang, Jinqiao Li, Yingying Xu, Xiaohong Song, Sizhen Su, Ximei Zhu, Michael V. Vitiello, Jie Shi, Yanping Bao, Lin Lu
Summary: Sleep disturbances are common in pregnancy and are often overlooked, but have significant associations with maternal complications and adverse fetal outcomes, particularly with conditions such as pre-eclampsia, gestational hypertension, and cesarean section.
SLEEP MEDICINE REVIEWS
(2021)
Article
Environmental Sciences
Ratika Kumar, Parivash Eftekhari, Gillian Sandra Gould
Summary: Bushfires pose significant environmental health risks for residents in affected areas, particularly disadvantaged individuals and those with pre-existing health conditions, such as pregnant women. There is currently a lack of evidence on the combined impact of bushfire smoke and tobacco smoke on pregnant populations, indicating the need for further research.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Gastroenterology & Hepatology
Parul Tandon, Eugenia Y. Lee, Cynthia Maxwell, Lara Hitz, Lindsy Ambrosio, Levinus Dieleman, Brendan Halloran, Karen Kroeker, Vivian M. Huang
Summary: Elevated fecal calprotectin levels during pregnancy in patients with inflammatory bowel disease may be associated with adverse pregnancy outcomes, serving as a potential marker for prediction.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Psychology, Clinical
Michele L. Okun, Vanessa Obetz, Leilani Feliciano
Summary: The study found that longer and more variable sleep latency, as well as shorter sleep duration, are associated with shorter gestational age or lower birth weight infants. The findings also suggest that among a low-risk, healthy sample of pregnant women, sleep disturbance does not pose a substantial risk for adverse delivery outcomes.
INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE
(2021)
Review
Nutrition & Dietetics
Heng Zhang, Shumin Wang, Lingjin Tuo, Qixiao Zhai, Jingjing Cui, Daozhen Chen, Dexiang Xu
Summary: Vitamin D plays an important role in pregnancy, with low levels being associated with adverse pregnancy outcomes. This review summarizes the potential mechanisms of how vitamin D regulates these outcomes and aims to provide a basis for public health intervention strategies.
Article
Psychology, Mathematical
Ulrich Knief, Wolfgang Forstmeier
Summary: The study finds that Gaussian models are robust to non-normal data, with p values remaining reliable in most conditions and showing good power. Parameter estimates are mostly unbiased and precise, except in cases of influential outliers or small sample sizes/highly skewed predictor distributions. Data transformation and visual inspection for outliers and heteroscedasticity are recommended before analysis.
BEHAVIOR RESEARCH METHODS
(2021)
Article
Endocrinology & Metabolism
Sigridur Bjornsdottir, Bart Clarke, Outi Makitie, Anna Sandstrom, Eleonor Tiblad, Tim Spelman, Olle Kampe
Summary: The study found that pregnant women with chronic hypoPT are more likely to have accompanying diabetes and chronic kidney disease compared to the control group, and are at increased risk of induction of labor and slightly lower infant birth weight.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Endocrinology & Metabolism
Emily A. Rosenberg, Ellen W. Seely
Summary: Cardiovascular disease is the leading cause of death for women, and adverse pregnancy outcomes such as gestational diabetes and preeclampsia are unique risk factors. However, these risk factors are often overlooked by providers. This mini-review focuses on the relationship between gestational diabetes, preeclampsia, and cardiovascular disease, as well as the mechanisms and management strategies for women with a history of adverse pregnancy outcomes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Psychology, Clinical
Delainey L. Wescott, Peter L. Franzen, Brant P. Hasler, Megan A. Miller, Adriane M. Soehner, Stephen F. Smagula, Meredith L. Wallace, Martica H. Hall, Kathryn A. Roecklein
Summary: This study aims to clarify the nature and extent of hypersomnolence in seasonal affective disorder (SAD) using multiple measurements. The results suggest that hypersomnolence is not a poor characterization of SAD, and self-reported hypersomnia captures multiple sleep disruptions.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Multidisciplinary
Minxuan Huang, Donald L. Bliwise, Martica H. Hall, Dayna A. Johnson, Richard P. Sloan, Amit Shah, Jack Goldberg, Yi-An Ko, Nancy Murrah, Oleksiy M. Levantsevych, Lucy Shallenberger, Rami Abdulbagki, J. Douglas Bremner, Viola Vaccarino
Summary: This study evaluated the association of depression with sleep disturbance in 246 members of the Vietnam Era Twin Registry. The findings suggest that depression is linked to REM sleep disruption, sleep fragmentation, and sleep variability, but not with sleep architecture or sleep-disordered breathing. The results were consistent regardless of zygosity, major depression diagnosis, comorbid PTSD, or antidepressant use.
ANNALS OF BEHAVIORAL MEDICINE
(2022)
Article
Clinical Neurology
Brian N. Chin, Eunjin L. Tracy, H. Matt Lehrer, Lucas W. Carroll, Precious N. Lacey, Sarah K. Kimutis, Daniel J. Buysse, Martica H. Hall
Summary: The study found that social integration is closely linked to sleep quality in older adults during the COVID-19 pandemic, especially in women. Additional research is needed to further understand the mechanisms and moderators of this relationship.
BEHAVIORAL SLEEP MEDICINE
(2022)
Article
Biology
Marie Tuft, Martica H. Hall, Robert T. Krafty
Summary: This article introduces a new approach to time-frequency analysis that decomposes the time-varying power spectrum into orthogonal rank-one layers in time and frequency. This provides a parsimonious representation that illustrates relationships between power at different times and frequencies.
Article
Cell Biology
H. Matthew Lehrer, Lauren E. Chu, Martica H. Hall, Kyle W. Murdock
Summary: Poor sleep quality may impair systemic mitochondrial bioenergetics, and in this study, sleep efficiency was found to be positively correlated with maximal respiration and spare capacity. Lower sleep efficiency and longer sleep duration were associated with lower Bioenergetic Health Index in age-, sex-, and body mass index-adjusted models, indicating a relationship between sleep and systemic bioenergetic function in humans.
Article
Psychiatry
Brian N. Chin, Kristina D. Dickman, Rachel E. Koffer, Sheldon Cohen, Martica H. Hall, Thomas W. Kamarck
Summary: Socially integrated individuals have lower risk of cardiovascular disease, partially due to their greater nocturnal blood pressure dipping, which is explained by better sleep regularity among these individuals.
PSYCHOSOMATIC MEDICINE
(2022)
Article
Psychiatry
Meredith L. Wallace, Nicholas Kissel, Martica H. Hall, Anne Germain, Karen A. Matthews, Wendy M. Troxel, Peter L. Franzen, Daniel J. Buysse, Charles Reynolds, Kathryn A. Roecklein, Heather E. Gunn, Brant P. Hasler, Tina R. Goldstein, Dana L. McMakin, Eva Szigethy, Adriane M. Soehner
Summary: This study used individual-level cross-sectional data to characterize age trends and sex differences in sleep dimensions across the healthy human life span. It found that sleep onset time and duration varied across different age groups, with differences between sexes also noted.
PSYCHOSOMATIC MEDICINE
(2022)
Article
Clinical Neurology
Meredith L. Wallace, Soomi Lee, Katie L. Stone, Martica H. Hall, Stephen F. Smagula, Susan Redline, Kristine Ensrud, Sonia Ancoli-Israel, Daniel J. Buysse
Summary: Similar sleep health profiles were identified in older men and women, with inadequate sleep health features associated with increased mortality risk. Research suggests that interventions targeting specific sleep health characteristics could potentially reduce mortality risk in older adults.
Article
Psychology, Applied
Eunjin L. Tracy, Brian Chin, H. Matthew Lehrer, Lucas W. Carroll, Daniel J. Buysse, Martica H. Hall
Summary: Stress during the COVID-19 pandemic has a significant impact on the health of older adults, particularly in terms of sleep health. This study explores the associations between perceived stress and various health outcomes among older adults, including mental health, physical health, and overall perceived health. The study also examines the moderating effect of coping strategies on these associations.
Article
Gerontology
Sarah T. Stahl, Salvatore P. Insana, Martica H. Hall, Daniel J. Buysse
Summary: This study investigated the association between retrospectively reported sleep disturbances during childhood and adolescence and current symptoms of depression and anxiety in older adults. The results suggest that pediatric sleep disturbances may be a biobehavioral signal for the development of poor emotional health across the lifespan.
INTERNATIONAL JOURNAL OF AGING & HUMAN DEVELOPMENT
(2022)
Article
Cardiac & Cardiovascular Systems
Minxuan Huang, Donald L. Bliwise, Amit Shah, Dayna A. Johnson, Gari D. Clifford, Martica H. Hall, Robert T. Krafty, Jack Goldberg, Richard Sloan, Yi-An Ko, Giulia Da Poian, Erick A. Perez-Alday, Nancy Murrah, Oleksiy M. Levantsevych, Lucy Shallenberger, Rami Abdulbaki, Viola Vaccarino
Summary: Through a co-twin control study, it was found that daytime HRV is bidirectionally associated with sleep dimensions, while nighttime HRV has no association with sleep measures. Dysfunctions in autonomic regulation during wakefulness can lead to subsequent shorter sleep duration and worse sleep continuity, and their influence on each other may extend beyond 24 hours.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Multidisciplinary Sciences
Viola Vaccarino, Amit J. J. Shah, Valeria Moncayo, Jonathon A. A. Nye, Marina Piccinelli, Yi-An Ko, Xin Ma, Nancy Murrah, Lucy Shallenberger, Emily Driggers, Nour Jajeh, Ammer Haffar, Omar Al-Abboud, Paolo Raggi, Martica H. H. Hall, Richard P. P. Sloan, Jack Goldberg, Nicholas L. L. Smith, Ernest V. V. Garcia, Arshed A. A. Quyyumi, J. Douglas Bremner, Donald L. L. Bliwise
Summary: This study found that twins with obstructive sleep apnea (OSA) had abnormal myocardial perfusion, suggesting subclinical myocardial scarring or infarction. The risk of abnormal myocardial perfusion was highest in twin pairs where both twins had OSA.
Article
Clinical Neurology
Leslie M. Swanson, Michelle M. Hood, Martica H. Hall, Nancy E. Avis, Hadine Joffe, Alicia Colvin, Kristine Ruppert, Howard M. Kravitz, Genevieve Neal-Perry, Carol A. Derby, Rachel Hess, Sioban D. Harlow
Summary: Examining actigraphy-assessed sleep timing and regularity in early late life women, this study found that sleep timing outside of the 2:00-4:00 AM range and sleep irregularity were associated with psychological health issues.
Article
Clinical Neurology
Ashlyn Runk, H. Matthew Lehrer, Meryl A. Butters, Daniel J. Buysse, Marissa A. Evans, Robert T. Krafty, Martica H. Hall
Summary: This study compared neurocognitive function between retired night shift workers and retired day workers, finding that retired night shift workers performed poorer on attention and executive function, suggesting an increased risk for future dementia.
Meeting Abstract
Clinical Neurology
Meredith Wallace, Soomi Lee, Katie Stone, Martica Hall, Stephen Smagula, Susan Redline, Kristine Ensrud, Sonia Ancoli-Israel, Daniel Buysse
