Article
Nutrition & Dietetics
Juan Sun, Zhen Liu, Zimu Zhang, Ziyang Zeng, Weiming Kang
Summary: This study revealed that adults with prediabetes and T2DM had higher fat content, and fat mass decreased with disease duration in T2DM patients. The associations of diabetes status with fat mass distribution were opposite to those observed in non-diabetic and prediabetic participants.
FRONTIERS IN NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Ashwinkumar Modi, Rajendra Gadhavi, Cynthia M. Perez, Kaumudi Joshipura
Summary: This study found that lower baseline adiposity and higher reduction in adiposity were associated with regression of prediabetes/diabetes among individuals with overweight/obesity.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Endocrinology & Metabolism
R. Qiu, B. Wu, Y. He, S. Huang, S. Wang, H. Li, F. Zheng
Summary: This study aimed to investigate the effect of aging on the prevalence of prediabetes and diabetes, and the influence of aging on the associations among adipose mass, redistribution, beta cell function, and the prevalence of hyperglycemia. The study found that the prevalence of prediabetes and diabetes increased with age. Central obesity may be more related to the development of hyperglycemia in younger people.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Public, Environmental & Occupational Health
Kevin L. Joiner, Mackenzie P. Adams, Kathryn A. Lee, Gretchen Piatt, Matthew A. Davis
Summary: The study aimed to examine the differences in perceived risk for diabetes by race and ethnicity among U.S. adults with undiagnosed prediabetes. The study found that the perceived risk for diabetes did not change significantly in any racial and ethnic groups. Non-Hispanic Black and Hispanic populations had a lower perceived risk for diabetes compared to Non-Hispanic White population.
PREVENTIVE MEDICINE
(2022)
Article
Pharmacology & Pharmacy
Katharina Schuetz, Sophia Theres Pallenberg, Julia Kontsendorn, David DeLuca, Cinja Sukdolak, Rebecca Minso, Tina Buettner, Martin Wetzke, Christian Dopfer, Annette Sauer-Heilborn, Felix C. Ringshausen, Sibylle Junge, Burkhard Tuemmler, Gesine Hansen, Anna-Maria Dittrich
Summary: Triple-combination therapy with ETI was introduced in Germany for CF patients. This study analyzed longitudinal data to identify the determinants of response to ETI in different age groups and severity levels. The results suggest that age and lung disease severity prior to ETI initiation play a role in the clinical response.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Aikaterini M. Kontochristopoulou, Kalliopi Karatzi, Eva Karaglani, Greet Cardon, Jemina Kivela, Katja Wikstrom, Violeta Iotova, Kaloyan Tsochev, Tsvetalina Tankova, Imre Rurik, Anett S. Radone, Stavros Liatis, Konstantinos Makrilakis, Luis A. Moreno, Yannis Manios
Summary: This study aimed to identify the main correlates of prediabetes and type 2 diabetes mellitus (T2DM) among adults from high-risk families for T2DM. The findings showed that male sex, younger age, lower waist circumference, lower fruit and berry consumption, lower fish consumption, and lower legume and full-fat dairy consumption were negatively correlated with prediabetes or T2DM.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Medicine, General & Internal
Mary R. Rooney, Andreea M. Rawlings, James S. Pankow, Justin B. Echouffo Tcheugui, Josef Coresh, A. Richey Sharrett, Elizabeth Selvin
Summary: This study analyzed prediabetes and diabetes risks among 3412 older adults in a community-based setting. It was found that in older age, high prevalence of prediabetes was observed, with more cases regressing to normal blood glucose levels or resulting in death rather than progressing to diabetes.
JAMA INTERNAL MEDICINE
(2021)
Article
Health Care Sciences & Services
Patricia Lizett Rodriguez-Carrillo, Priscila Irene Aguirre-Tostado, Maciste H. Macias-Cervantes, Jorge Alejandro Alegria-Torres, Claudia Luevano-Contreras
Summary: The study proposed Mexican adiposity indices (MAIs) and biochemical-anthropometric indices (BAIs), that performed well in identifying CR and MetS in Mexican adults. The VFA cut-off value of 100.3 cm(2) was found to be effective in identifying CR in Mexican men.
Article
Endocrinology & Metabolism
Yoosun Cho, Yoosoo Chang, Seungho Ryu, Yejin Kim, Hyun-Suk Jung, Jeonggyu Kang, In Young Choi, Chan-won Kim, Hyungseok Oh, Sarah H. Wild, Christopher D. Byrne
Summary: This study evaluated the effect of changes in prediabetes on subclinical atherosclerosis and found that persistence of prediabetes or progression to diabetes increased the risk of coronary artery calcification.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Ying Shang, Laura Fratiglioni, Davide Liborio Vetrano, Abigail Dove, Anna-Karin Welmer, Weili Xu
Summary: The study found that both prediabetes and diabetes are associated with accelerated functional decline and disability progression, with cardiovascular diseases potentially mediating these associations.
Article
Endocrinology & Metabolism
Sarah S. Casagrande, Christine Lee, Luke E. Stoeckel, Andy Menke, Catherine C. Cowie
Summary: This study aimed to investigate the association between diabetes status, glycemia, and cognitive function in older adults, revealing a link between diabetes and mild cognitive dysfunction. The research found that cognitive function scores decreased with increasing blood glucose levels, with significant effects observed for animal fluency and DSST even after comprehensive adjustment.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Public, Environmental & Occupational Health
Gabriela Lima de Melo Ghisi, Mariana Balbi Seixas, Daniele Sirineu Pereira, Ligia Loiola Cisneros, Danielle Guedes Andrade Ezequiel, Crystal Aultman, Nicole Sandison, Paul Oh, Lilian Pinto da Silva
Summary: This article describes the development of a structured patient education program for Brazilians living with diabetes or prediabetes, including a 4-phase needs assessment and the translation and cultural adaptation of the patient guide.
Article
Endocrinology & Metabolism
Yuta Suzuki, Hidehiro Kaneko, Akira Okada, Satoshi Matsuoka, Hidetaka Itoh, Katsuhito Fujiu, Nobuaki Michihata, Taisuke Jo, Norifumi Takeda, Hiroyuki Morita, Satoko Yamaguchi, Koichi Node, Toshimasa Yamauchi, Hideo Yasunaga, Issei Komuro
Summary: This study examined the association between cardiovascular health (CVH) metrics and the annual incidence of diabetes in young adults with prediabetes. The results showed that an increasing number of nonideal CVH metrics were associated with an increased risk of diabetes. Improving CVH metrics could reduce the risk of developing diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Public, Environmental & Occupational Health
Junxiu Liu, Stella S. Yi, Rienna Russo, Ming Wen, Yan Li
Summary: The study aimed to describe the current trend of diabetes and prediabetes among US adults, assess disparities among population subgroups, and examine their relationship with sociodemographic factors. The prevalence of diabetes and prediabetes significantly increased from 1999 to 2018, with persistent disparities among racial and ethnic minorities, socioeconomically disadvantaged populations, and adults with obesity.
Article
Cardiac & Cardiovascular Systems
Arnaud D. Kaze, Sebhat Erqou, Prasanna Santhanam, Alain G. Bertoni, Rexford S. Ahima, Gregg C. Fonarow, Justin B. Echouffo-Tcheugui
Summary: This study found that greater variability in adiposity indices in individuals with type 2 diabetes was associated with a higher risk of incident heart failure, independently of traditional risk factors and baseline adiposity levels.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Albert Teis, Esmeralda Castelblanco, German Cediel, Nuria Amigo, Josep Julve, Josep Ribalta, Montse Guardiola, Josep Franch, Marcelino Bermudez-Lopez, Pau Codina, Josep Lupon, Didac Mauricio, Nuria Alonso, Antoni Bayes-Genis
Summary: Patients with chronic heart failure have significant differences in their lipoprotein profile compared to unaffected controls, which may be associated with cardiovascular risk. Characteristic changes in lipid concentrations and lipoprotein particle size are observed in patients with chronic heart failure.
REVISTA ESPANOLA DE CARDIOLOGIA
(2022)
Article
Medicine, Research & Experimental
Josep Franch-Nadal, Samuel J. P. Malkin, Barnaby Hunt, Virginia Martin, Maria Gallego Estebanez, Josep Vidal
Summary: This study aimed to evaluate the long-term cost-effectiveness of oral semaglutide versus other medications for type 2 diabetes treatment in Spain, demonstrating that oral semaglutide was superior in improving quality of life and reducing costs.
ADVANCES IN THERAPY
(2022)
Article
Nutrition & Dietetics
Gemma Chiva-Blanch, Oriol Giro, Montserrat Cofan, Alfonso L. Calle-Pascual, Elias Delgado, Ramon Gomis, Amanda Jimenez, Josep Franch-Nadal, Gemma Rojo Martinez, Emilio Ortega
Summary: This study aims to evaluate the association between fatty acids in red blood cell membranes and incident type 2 diabetes in a Spanish population. The results showed that lower percentages of certain fatty acids and higher percentages of others were associated with worse glucose metabolism. Higher percentages of certain fatty acids were also associated with lower risk of diabetes. Dietary patterns rich in vegetables were independently associated with lower risk of glucose regulation deterioration and incident diabetes.
Article
Endocrinology & Metabolism
Suping Ling, Francesco Zaccardi, Bogdan Vlacho, Ping Li, Jordi Real Gatius, Manel Mata-Cases, Josep Franch-Nadal, Mikhail N. Kosiborod, Clare Gillies, Peter Fenici, Didac Mauricio, Baiju R. Shah, Kamlesh Khunti
Summary: This study aimed to understand the geographical and temporal patterns in the excess mortality risk associated with type 2 diabetes (T2D) in three high-income countries. The results showed similar diabetes gaps between Ontario and England, particularly in elderly subjects, while Catalonia had lower mortality rates in men with T2D from the age of 60 years.
DIABETES OBESITY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Bogdan Vlacho, Flora Lopez Simarro, Manel Mata-Cases, Sonia Miravet, Jose Escribano-Serrano, David Asensio, Xavi Cortes, Josep Franch-Nadal
Summary: The study aimed to determine the degree and factors related to non-insulin antidiabetic drug adherence in people with type 2 diabetes mellitus treated in primary care centers in Spain. Results showed that adherence to NIADs was suboptimal, with higher adherence among metformin users and lower adherence among thiazolidinedione users. HbA1c and ARMS-e items could be used as indicators to encourage treatment changes for improving T2DM control.
PRIMARY CARE DIABETES
(2022)
Article
Endocrinology & Metabolism
Magdalena Bundo, Bogdan Vlacho, Judit Llussa, Ramon Puig-Treserra, Manel Mata-Cases, Xavier Cos, Edward B. Jude, Josep Franch-Nadal, Didac Mauricio
Summary: This study aimed to assess the prevalence of diabetic foot disease (DFD) and its associated risk factors among subjects attending primary care centers in Catalonia (Spain). The results showed that male sex, duration of diabetes, diabetes complications, and previous history of DFD were strongly associated with the presence of DFD.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Angels Mollo, Bogdan Vlacho, Monica Gratacos, Manel Mata-Cases, Esther Rubinat, Anna Berenguera, Jordi Real, Ramon Puig-Treserra, Xavier Cos, Josep Franch-Nadal, Kamlesh Khunti, Didac Mauricio, INTEGRA Res grp
Summary: A specially designed multicomponent healthcare intervention can improve glycaemic control in subjects with poorly controlled type 2 diabetes.
DIABETES OBESITY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Didac Mauricio, Bogdan Vlacho, Emilio Ortega, Xavier Cos-Claramunt, Manel Mata-Cases, Jordi Real, Berta Fernandez-Camins, Josep Franch-Nadal
Summary: The aim of this study was to estimate the incidence and risk factors for fatal and non-fatal events among COVID-19 infected subjects with obesity or diabetes during the initial three epidemiological waves in the region. A retrospective cohort study was conducted using a primary care database to identify individuals with COVID-19, stratifying them based on diabetes mellitus or obesity. Results showed that fatal events were more common among individuals with diabetes, particularly during the first wave. The number of study events decreased in the second and third waves. Diabetes was found to be a risk factor for fatal events, while obesity was only a risk factor when adjusted for age, sex, diabetes, and COVID-19 waves. HIV, cancer, and autoimmune diseases were also identified as risk factors for mortality among subjects with COVID-19 in the fully-adjusted model.
PRIMARY CARE DIABETES
(2023)
Article
Endocrinology & Metabolism
Maria Teresa Julian, Silvia Ballesta, Guillem Pera, Alejandra Perez-Montes de Oca, Berta Soldevila, Llorenc Caballeria, Rosa Morillas, Carmen Exposito, Alba Martinez-Escude, Manel Puig-Domingo, Josep Franch-Nadal, Pere Toran, Kenneth Cusi, Josep Julve, Didac Mauricio, Nuria Alonso
Summary: This study investigated longitudinal changes in liver stiffness measurement (LSM) in the general adult population without known liver disease and found that abdominal obesity and dysglycemia were the main risk metabolic factors associated with the development of moderate-to-advanced liver fibrosis.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Orthopedics
Magdalena Bundo, Bogdan Vlacho, Judit Llussa, Isabel Bobe, Meritxell Aivar, Carmen Ciria, Ana Martinez-Sanchez, Jordi Real, Manel Mata-Cases, Xavier Cos, Montserrat Doria, Jordi Viade, Josep Franch-Nadal, Didac Mauricio
Summary: This study evaluated the prognosis of diabetic foot ulcer (DFU) in primary care centers in Catalonia, Spain, over a 12-month period. The results showed high mortality, amputation, and recurrence rates, and low healing rate among patients with DFU. Diabetes complications and high PEDIS/SINBAD scores were associated with poor clinical outcomes.
JOURNAL OF FOOT AND ANKLE RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Marina Idalia Rojo-Lopez, Marcelino Bermudez-Lopez, Eva Castro, Cristina Farras, Gerard Torres, Reinald Pamplona, Albert Lecube, Jose Manuel Valdivielso, Elvira Fernandez, Josep Julve, Esmeralda Castelblanco, Josep Franch-Nadal, Nuria Alonso, Minerva Granado-Casas, Didac Mauricio
Summary: The aim of this study was to evaluate the association between the Mediterranean diet and subclinical atherosclerotic disease. The results showed that higher adherence to the Mediterranean diet was associated with a lower risk of atherosclerotic plaques, and moderate or high adherence to the diet was associated with a lower number of plaques.
Article
Medicine, General & Internal
Sergio Valdes, Viyey Doulatram-Gamgaram, Cristina Maldonado-Araque, Eva Garcia-Escobar, Sara Garcia-Serrano, Wasima Oualla-Bachiri, Marta Garcia-Vivanco, Juan Luis Garrido, Victoria Gil, Fernando Martin-Llorente, Alfonso Calle-Pascual, Luis Castano, Elias Delgado, Edelmiro Menendez, Josep Franch-Nadal, Sonia Gaztambide, Joan Girbes, F. Javier Chaves, Jose L. Galan-Garcia, Gabriel Aguilera-Venegas, Joan Carles Vallve, Nuria Amigo, Montse Guardiola, Josep Ribalta, Gemma Rojo-Martinez
Summary: The study aimed to assess the associations between exposure to air pollutants and lipoprotein measures in the adult population of Spain. The results showed that exposure to particulate matter and nitrogen dioxide was associated with lower levels of high-density lipoprotein cholesterol and particles, as well as increased risk of low high-density lipoprotein cholesterol and particles. Subgroup analysis further revealed that the effects of particulate matter and nitrogen dioxide were more pronounced in men and individuals with obesity.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Medicine, General & Internal
Pedro Romero-Aroca, Raquel Verges, Jordi Pascual-Fontanilles, Aida Valls, Josep Franch, Joan Barrot, Xavier Mundet, Alex La Torre, Antonio Moreno, Ramon Sagarra, Josep Basora, Eugeni Garcia-Curto, Marc Baget-Bernaldiz
Summary: This study found that arterial hypertension, high HbA1c levels, microalbuminuria, high LDL-cholesterol, high TC/HDL-C index, high non-HDL-C/HDL-C index, the use of statins, and high body mass index are the main factors influencing the development of diabetic retinopathy. Conversely, high HDL-cholesterol levels and the use of fibrates have a protective effect.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Angel Ortiz-Zuniga, Olga Simo-Servat, Judit Amigo, Monica Sanchez, Carla Morer, Josep Franch-Nadal, Regina Mayor, Tim Snel, Rafael Simo, Cristina Hernandez
Summary: This study evaluated the efficacy of self-management of insulin titration based on information received by the Short Message Service (SMS). The results showed that SMS-guided titration improved glycemic control and significantly improved psychological aspects related to insulin treatment.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Primary Health Care
V. Martin-Sanchez, A. Ruiz-Garcia, F. Vitelli-Storelli, A. Serrano-Cumplido, A. Barquilla-Garcia, R. M. Mico-Perez, V. Olmo-Quintana, A. Calderon-Montero, A. Segura-Fragoso
Summary: This study evaluates the impact of vaccination on COVID-19 case-fatality rates (CFRs) during the third and fifth epidemic waves in Spain. The results show a decrease in CFRs in the fifth wave compared to the third wave, with higher rates in men and older individuals. There is a direct correlation between vaccination coverage and decreased CFRs.
MEDICINA DE FAMILIA-SEMERGEN
(2023)
