Article
Chemistry, Analytical
Mir Ali Farajzadeh, Somayeh Pasandi, Ali Mohebbi, Mohammad Reza Afshar Mogaddam
Summary: In this study, a magnetic iron (III) oxinate nanocomposite with high adsorption capacity and saturation magnetization was synthesized and used for pesticide extraction from fruit juice and fruit samples. The method showed low limits of detection and quantification, as well as good repeatability and enrichment.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Lidia Akemi Akamine, Deyber Arley Vargas Medina, Fernando Mauro Lancas
Summary: In this study, a graphene oxide/magnetite (GO-Fe3O4) nanocomposite was synthesized and utilized in the magnetic solid-phase extraction (MSPE) of gingerols from various ginger products. The developed MSPE method combined with HPLC-MS/MS analysis demonstrated high selectivity and consistent analytical confidence, with LODs ranging between 2 and 3 μg L-1. The technique showed good linearity, accuracy, and practicality, making it a valuable tool for quality control of commercial ginger-containing products.
Article
Chemistry, Analytical
Preeyaporn Phosiri, Rodjana Burakham
Summary: A new magnetic material based on deep eutectic solvent functionalized mixed iron hydroxides coated with silica was successfully utilized for the magnetic solid-phase extraction of organochlorine pesticides. The developed method showed excellent enrichment capability for organochlorine pesticides with a wide linear range, low detection and quantification limits, and satisfactory recoveries for determining organochlorine residues in agricultural products. This promising sorbent can effectively preconcentrate organochlorine residues.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Environmental Sciences
Hassan Sereshti, Atiyeh Amirafshar, Ammar Kadi, Hamid Rashidi Nodeh, Shahabaldin Rezania, Hien Y. Hoang, Anahita Barghi, Yasser Vasseghian
Summary: A novel adsorbent, 3D-MG@AuNPs, was developed for the extraction of specific organophosphorus pesticides (OPPs) from wastewater and tap water samples. The nanocomposite was characterized and evaluated for extraction efficiency under various parameters. The amounts of chosen OPPs were determined using gas chromatography microelectron capture (mu ECD-GC) method.
Article
Biochemical Research Methods
Adeleh Yadeghari, Mir Ali Farajzadeh
Summary: This study successfully synthesized an economically affordable and environmentally friendly sorbent based on the extract of Mentha piperita leaves, which was used for the extraction and preconcentration of various pesticides from samples and monitored using gas chromatography-tandem mass spectrometry.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Chemistry, Analytical
Ying Shi, Huang-Fei Jin, Min-Zhen Shi, Jun Cao, Li-Hong Ye
Summary: In this study, a miniaturized solid phase extraction method and supercritical fluid chromatography combined with ion mobility quadrupole time-of-flight mass spectrometry were used for the qualitative and quantitative analysis of carbamate pesticide residues. The method was validated and applied successfully to the enrichment and detection of carbamate residues in ginger samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Environmental Sciences
Abdulaziz Ibrahim Almohana, Sattam Fahad Almojil, Abdulrhman Fahmi Alali, Khaled Twfiq Almoalimi
Summary: An efficient MOF-801/GO sorbent was fabricated and utilized for the detection of OSPs using GC-FPD. The proposed SPE method showed a linear dynamic range of 0.5-300 mu g L-1 and a detection limit of 0.1-1.1 mu g L-1 for OSP samples. The application of the MOF-801/GO sorbent in dSPE of OSP analytes proved to be a reliable and sensitive methodology for pesticides monitoring in various environmental samples.
Article
Chemistry, Analytical
Maryam Farahmandi, Yadollah Yamini, Mahroo Baharfar, Monireh Karami
Summary: A customized microfluidic system was utilized for magnetic solid phase extraction of parabens, achieving efficient extraction and magnetic separation. Magnetite nanoparticles were synthesized and various chemical and instrumental parameters were optimized for characterization and stability of the particles. The method was successfully applied for the extraction of parabens from fruit juice, sunscreen, and urine samples with favorable accuracy and precision.
ANALYTICA CHIMICA ACTA
(2021)
Article
Environmental Sciences
Zahra Sotoudehnia Korrani, Elham Khalili, Hesam Kamyab, Wan Aini Wan Ibrahim, Haslenda Hashim
Summary: In this study, cyanopropyl-functionalized silica nanoparticles were prepared using a sol-gel approach and used as a sorbent for determining trace levels of OPPs in environmental water samples. The synthesis parameters and the performance of the sorbent were investigated, and figures of merit such as precision, linearity, LOQ, LOD, and recovery were evaluated. The designed SPE method was successfully applied to the determination of OPPs in real water samples and compared to commercial cartridges.
ENVIRONMENTAL RESEARCH
(2023)
Review
Chemistry, Analytical
Herbert Musarurwa, Luke Chimuka, Nikita Tawanda Tavengwa
Summary: Magnetic solid phase extraction (MSPE) for pesticide residues is gaining popularity due to the development of sorbents like metal organic frameworks (MOFs) with high adsorption capacities, particularly in the use of magnetic MIL and ZIF series of MOFs during pre-concentration. The application of MOFs, including the HKUST series, in MSPE pre-concentration of pesticides in complex matrices, while discussing the challenges associated with their use, is highlighted in this review.
MICROCHEMICAL JOURNAL
(2021)
Review
Chemistry, Applied
Mhd. Abd. Cader Mhd. Haniffa, Yern Chee Ching, Hazlee Azil Illias, Khadija Munawar, Shaliza Ibrahim, Dai Hai Nguyen, Cheng Hock Chuah
Summary: Cellulose with ample hydroxyl groups is used to fabricate cellulose supported magnetic sorbents for magnetic solid-phase extraction. CMS offers improved adsorption capabilities due to its high specific surface area, porous structure, and magnetic attraction feature.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Analytical
Mir Ali Farajzadeh, Shabnam Shaghaghipour, Maryam Abbaspour, Mohammad Reza Afshar Mogaddam
Summary: In this study, magnetic nanoparticles based on amorphous carbon were synthesized and used as a sorbent for the analysis of pesticides in fruit juice samples. The developed method of magnetic dispersive solid-phase extraction and dispersive liquid-liquid micro-extraction allowed for rapid and efficient enrichment of the analytes, resulting in high extraction recoveries.
ANALYTICAL SCIENCES
(2023)
Article
Chemistry, Analytical
Ranbir, Gagandeep Singh, Harupjit Singh, Navneet Kaur, Narinder Singh
Summary: Modern agricultural practice heavily relies on pesticides and herbicides, which have negative impacts on the environment and public health. This study developed an azodye-based sensor array for the detection and discrimination of pesticides and herbicides in food and soil samples using machine learning approaches. Automated multivariate analysis was used for the recognition of distinct patterns, enabling the selective and sensitive identification and discrimination of various target analytes.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Xu Dan, Li Ruiyi, Wang Qinsheng, Yang Yongqiang, Zhu Haiyan, Li Zaijun
Summary: This study presents the synthesis of a nickel-silver-graphene quantum dot-graphene hybrid with high oxidase-like activity and sensitive detection ability for malathion. In the presence of malathion, the hybrid exhibits multifunctional catalytic properties for colorimetric detection. The research results provide a promising platform for on-site pesticide detection.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Analytical
Ranbir, Gagandeep Singh, Harupjit Singh, Navneet Kaur, Narinder Singh
Summary: Modern agricultural practice heavily relies on pesticides and herbicides, which have negative impacts on the environment and public health. In this study, an azodye-based chromogenic sensor array combined with machine learning approaches was developed for the selective and sensitive detection and discrimination of pesticides and herbicides. The sensor array, utilizing the different photophysical properties of various metal ions, showed distinct patterns towards different target analytes. Automated multivariate analysis, such as hierarchical clustering analysis, principal component analysis, linear discriminant analysis, and partial least square regression, was employed for the recognition and processing of the obtained patterns. The developed sensor array was successfully used for the qualitative and quantitative determination of target analytes, showing good linear correlation and detection limits.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).