Anti-hypertensive treatment preserves appetite suppression while preventing cardiovascular adverse effects of tesofensine in rats

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The novel triple monoamine reuptake inhibitor tesofensine induces sustained weight loss and improves glycemic control in the diet-induced obese rat: Comparison to sibutramine and rimonabant

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Tesofensine, a Novel Triple Monoamine Reuptake Inhibitor, Induces Appetite Suppression by Indirect Stimulation of α1 Adrenoceptor and Dopamine D1 Receptor Pathways in the Diet-Induced Obese Rat

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Effect of Sibutramine on Cardiovascular Outcomes in Overweight and Obese Subjects

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Semi-Mechanistic Population Pharmacokinetic Drug-Drug Interaction Modelling of a Long Half-Life Substrate and Itraconazole

(2009) Thorsten Lehr et al.   CLINICAL PHARMACOKINETICS

Tesofensine – a novel potent weight loss medicine

(2009) Sheila A Doggrell   EXPERT OPINION ON INVESTIGATIONAL DRUGS

In Vitro and In Vivo Pharmacodynamic Properties of Metoprolol in Fructose-fed Hypertensive Rats

(2009) Carla Andrea Di Verniero et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial

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Relation Between Obesity and Blunted Striatal Response to Food Is Moderated by TaqIA A1 Allele

(2008) E. Stice et al.   SCIENCE

Contribution of the active metabolite M1 to the pharmacological activity of tesofensinein vivo: a pharmacokinetic-pharmacodynamic modelling approach

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