Article
Endocrinology & Metabolism
Oddrun Kristiansen, Manuela Zucknick, Trine M. Reine, Svein O. Kolset, Thomas Jansson, Theresa L. Powell, Guttorm Haugen, Tore Henriksen, Trond M. Michelsen
Summary: The study suggests that placental weight is the main mediator linking pregestational BMI and gestational weight gain to birthweight and neonatal fat mass percentage. Maternal mediators only partially mediate the effect of pBMI, while placental weight is the main mediator in this association.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Gemma Carreras-Badosa, Elsa Puerto-Carranza, Berta Mas-Pares, Ariadna Gomez-Vilarrubla, Bernat Gomez-Herrera, Ferran Diaz-Roldan, Elena Riera-Perez, Francis de Zegher, Lourdes Ibanez, Judit Bassols, Abel Lopez-Bermejo
Summary: The study found that serum α-Klotho concentrations were negatively associated with obesity-related parameters in girls, particularly in those experiencing weight gain. α-Klotho may prove to be a protective factor against the accumulation of visceral fat.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Psychiatry
Yuying Qiu, Meijuan Li, Yonghui Zhang, Ying Liu, Yongping Zhao, Jing Zhang, Qiong Jia, Jie Li
Summary: Berberine could reduce weight gain in schizophrenia patients, with significant weight loss observed in the berberine group compared to placebo. The effect may be related to the regulation of leptin levels.
ASIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Nutrition & Dietetics
Tatiana Papazian, Pascale Salameh, Georges Abi Tayeh, Assaad Kesrouani, Carla Aoun, Mia Abou Diwan, Lydia Rabbaa Khabbaz
Summary: This study aimed to identify the dietary patterns of Lebanese pregnant women and their correlation with maternal and neonatal outcomes. Three dietary patterns were identified: Westernized, Mixed, and Neo-Mediterranean. These patterns were found to be correlated with pre-gestational BMI and some maternal variables, but not with maternal and neonatal outcomes.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Jessica Fry, Shelley A. Wilkinson, Jane Willcox, Michaela Henny, Lisa McGuire, Taylor M. Guthrie, Nina Meloncelli, Susan de Jersey
Summary: This study aimed to explore the experiences and perceptions of women who were referred but did not attend or complete the LWdP program, in order to improve the program and provide better antenatal care. Three key themes were identified: program content not meeting expectations, the need for flexible and multimodal healthcare, and information sharing not meeting women's needs. Interventions to improve engagement and patient-centered care include adapting the LWdP program, training and supporting healthcare professionals, and promoting positive health behaviors.
Article
Public, Environmental & Occupational Health
Sara Ornaghi, Simona Fumagalli, Sofia Galimberti, Alice Margherita Ornago, Valentina Brivio, Laura Lambicchi, Antonella Nespoli, Patrizia Vergani
Summary: This study investigated the potential effects of abnormal gestational weight gain (GWG) among low-risk, healthy pregnant women with no comorbidities or gestational complications. The results showed that abnormal GWG was associated with increased risk of adverse perinatal outcomes.
JOURNAL OF WOMENS HEALTH
(2023)
Article
Nutrition & Dietetics
Nina R. W. Geiker, Faidon Magkos, Helle Zingenberg, Jens Svare, Elizaveta Chabanova, Henrik S. Thomsen, Christian Ritz, Arne Astrup
Summary: Increasing dietary protein and reducing glycemic index during the last two trimesters of pregnancy can effectively reduce gestational weight gain and risk of complications, as well as decrease the rate of cesarean deliveries among overweight or obese pregnant women.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Vanessa Averof Honorato de Almeida, Rafaela Alkmin da Costa, Cristiane de Freitas Paganoti, Fernanda Cristina Mikami, Ana Maria da Silva Sousa, Stela Verzinhasse Peres, Marco Antonio Borges Lopes, Rossana Pulcineli Vieira Francisco
Summary: This study found that the physical activity levels of pregnant women are related to weight gain outcomes, with low physical activity levels associated with insufficient weight gain. Additionally, inadequate dietary habits, low physical activity levels, and pregestational obesity may increase the risk of excessive weight gain in pregnant women with gestational diabetes mellitus.
Article
Nutrition & Dietetics
Enju Liu, Dongqing Wang, Anne Marie Darling, Nandita Perumal, Molin Wang, Willy Urassa, Andrea Pembe, Wafaie W. Fawzi
Summary: This study examined the effect of daily supplementation of pregnant women with multivitamins on gestational weight gain (GWG) in relation to the GWG recommendation by the Institute of Medicine (IOM). The results showed that multivitamin supplementation increased GWG and reduced the risk of severely inadequate and inadequate GWG among pregnant women in Tanzania.
JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Martina Vulin, Lucija Magusic, Ana-Maria Metzger, Andrijana Muller, Ines Drenjancevic, Ivana Jukic, Sinisa Sijanovic, Matea Lukic, Lorena Stanojevic, Erna Davidovic Cvetko, Ana Stupin
Summary: This study investigated diet quality in healthy pregnant women and found a higher Na-to-K ratio and suboptimal intake of vitamins and minerals. Excessive gestational weight gain was observed in some women, possibly due to insufficient physical activity.
Article
Environmental Sciences
Andrea L. Deierlein, Haotian Wu, Allan C. Just, Allison J. Kupsco, Joseph M. Braun, Emily Oken, Diana C. Soria-Contreras, Alejandra Cantoral, Ma Luisa Pizano, Nia McRae, Martha M. Tellez-Rojo, Robert O. Wright, Andrea A. Baccarelli
Summary: The study found that prenatal exposure to phthalates was negatively associated with gestational weight gain and positively associated with long-term changes in maternal weight. Further investigation is needed to understand how phthalates influence body composition and whether they contribute to the development of obesity and other cardiometabolic diseases in women.
ENVIRONMENTAL RESEARCH
(2022)
Article
Multidisciplinary Sciences
David W. DeGroot, Collin A. Sitler, Michael B. Lustik, Kelly L. Langan, Keith G. Hauret, Michael H. Gotschall, Alan P. Gehrich
Summary: The study findings suggest that extending postpartum convalescence by 6 weeks does not adversely affect the physical performance or BMI measures of Active Duty Army women. Important factors for recovery include pre- and post-pregnancy conditioning, weight management, weight gain during pregnancy, and consistent breastfeeding.
Article
Public, Environmental & Occupational Health
A. Rojas-Gulloso, L. Sanchez-Lerma, Marcela Montilla, F. Morales-Pulecio, E. Sarmiento-Rudolf, Ricardo Tapia-Reales
Summary: This study describes the health and infectious diseases with vertical transmission risk in migrant pregnant women from an area of the Colombian Caribbean from 2019 to 2021. The results show that syphilis is the most common infectious agent with a risk of vertical transmission, and there are also proportions of rubella and HIV antibodies in the pregnant women. These findings highlight the need for educational, prevention, and detection health programs to reduce prenatal infections in the pregnant migrant population and prevent fatal complications.
TRAVEL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Public, Environmental & Occupational Health
Jin Zhang, Rui Zhang, Jingjing Chi, Ya Li, Wenpei Bai
Summary: This study investigated the relationship between pre-pregnancy weight, gestational weight gain, and perinatal outcomes. The findings suggest that strict weight control during pregnancy is crucial for reducing maternal and infant complications, especially in the second and third trimesters. Additionally, pre-pregnancy BMI has a greater impact on birth weight and maternal and infant complications compared to gestational weight gain, potentially compromising the benefits of weight control during pregnancy. Therefore, weight control before pregnancy is recommended.
ARCHIVES OF PUBLIC HEALTH
(2023)
Article
Endocrinology & Metabolism
Veronica Perea, Andreu Simo-Servat, Carmen Quiros, Nuria Alonso-Carril, Maite Valverde, Xavier Urquizu, Antonio J. Amor, Eva Lopez, Maria-Jose Barahona
Summary: This study found that pregestational obesity is associated with a higher risk of ADHD in offspring of GDM pregnancies. However, excessive weight gain during pregnancy does not have an independent effect on ADHD risk. Only the joint association of obesity and excessive weight gain during pregnancy remains significant in relation to ADHD risk.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Clinical Neurology
Ricardo Bruna, David Lopez-Sanz, Fernando Maestu, Ann D. Cohen, Anto Bagic, Ted Huppert, Tae Kim, Rebecca E. Roush, Betz Snitz, James T. Becker
Summary: This study investigated the mechanisms behind Alzheimer's disease and found that patients with amnestic MCI showed a slowing of brain activity, which was not observed in individuals without subjective complaints. This raises interesting questions about this particular group of individuals and the underlying brain mechanisms behind their cognitive impairment.
CLINICAL EEG AND NEUROSCIENCE
(2023)
Article
Endocrinology & Metabolism
Milana A. Bochkur Dratver, Juliana Arenas, Tanayott Thaweethai, Chu Yu, Kaitlyn James, Emily A. Rosenberg, Michael J. Callahan, Melody Cayford, Jessica S. Tangren, Sarah N. Bernstein, Marie France Hivert, Ravi Thadhani, Camille E. Powe
Summary: In pregnant women with diabetes risk factors, fasting glucose levels decrease in the first trimester while post-load glucose levels increase later in pregnancy. These findings could help establish criteria for diagnosing hyperglycaemia early in pregnancy.
Article
Environmental Sciences
Emma Preston, Marie-France Hivert, Abby F. Fleisch, Antonia M. Calafat, Sharon K. Sagiv, Wei Perng, Sheryl L. Rifas-Shiman, Jorge E. Chavarro, Emily Oken, Ami R. Zota, Tamarra James-Todd
Summary: This study found that exposure to certain PFAS may increase the risk of gestational hypertension during pregnancy, with potential implications for maternal and child health outcomes.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Public, Environmental & Occupational Health
Nathan Cohen, Sabrina Faleschini, Sheryl L. Rifas-Shiman, Luigi Bouchard, Myriam Doyon, Olivier Simard, Melina Arguin, Guy Fink, Amy C. Alman, Russell Kirby, Henian Chen, Ronee Wilson, Kimberly Fryer, Patrice Perron, Emily Oken, Marie-France Hivert
Summary: The relationship between maternal hyperglycemia and offspring cortisol levels is still unclear.
JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE
(2023)
Article
Mathematical & Computational Biology
Zheng Wang, Zi Wang, Lingyun Lyu, Yu Cheng, Eric C. Seaberg, Samantha A. Molsberry, Ann Ragin, James T. Becker
Summary: In this study, a method for identifying cognitive impairment by using the difference of consecutive LMNC test statistics is proposed. Frequency modeling is used to predict the number of assessments for each participant, and a simple correction method is adopted to control the family-wise error rate. The method effectively controls the error rate in both simulation and real data.
STATISTICS IN MEDICINE
(2023)
Article
Pediatrics
Nidhi Ghildayal, Catherine Allard, Kasandra Blais, Myriam Doyon, Melina Arguin, Luigi Bouchard, Patrice Perron, Marie-France Hivert
Summary: The study found an association between maternal insulin sensitivity during pregnancy and adiposity measures in children. Lower maternal insulin sensitivity was correlated with higher child adiposity, particularly in central adiposity measures.
Article
Environmental Sciences
Pi-I D. Lin, Andres Cardenas, Sheryl L. Rifas-Shiman, Ami R. Zota, Marie-France Hivert, Izzuddin M. Aris, Alison P. Sanders
Summary: This study aimed to explore the association between trace elements and maternal kidney function during the first trimester of pregnancy. The findings suggest that high lead levels and low magnesium, selenium, and zinc levels are associated with decreased kidney function. Furthermore, the analysis of trace element mixtures shows that a higher concentration of non-essential trace elements is associated with reduced kidney function, while a higher concentration of essential trace elements is associated with improved kidney function.
ENVIRONMENTAL RESEARCH
(2023)
Review
Public, Environmental & Occupational Health
Emily Oken, Theresa M. Bastain, Nicole Bornkamp, Carrie Breton, Rebecca C. Fry, Diane R. Gold, Marie-France Hivert, Steve Howland, Daniel J. Jackson, Christine C. Johnson, Kyra Jones, MollyAn Killingbeck, T. Michael O'Shea, Marleny Ortega, Dennis Ownby, Frederica Perera, Julie Rollins, Julie B. Herbstman
Summary: High-quality evidence from prospective longitudinal studies in humans is essential for understanding the developmental origins of health and disease. This paper discusses the challenges faced by birth cohort studies and provides recommendations for long-term funding, maintaining contact with participants, maximizing engagement, and addressing sensitive topics. Successful longitudinal follow-up requires flexibility, adaptability, and appropriate incentives.
JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE
(2023)
Article
Public, Environmental & Occupational Health
Ella Parsons, Sheryl L. Rifas-Shiman, Anne K. Bozack, Andrea A. Baccarelli, Dawn L. DeMeo, Marie-France Hivert, Lode Godderis, Radu-Corneliu Duca, Emily Oken, Andres Cardenas
Summary: The prenatal environment may program health and disease susceptibility via epigenetic mechanisms. This study found associations between maternal trimester-specific intake of micronutrients and global DNA methylation and 5-hydroxymethylation in cord blood, with some associations persisting into early childhood.
JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Chloe Sarnowski, Matthew P. Conomos, Ramachandran S. Vasan, James B. Meigs, Josee Dupuis, Ching-Ti Liu, Aaron Leong
Summary: The effects of genetic burden on obesity risk and cardiovascular disease differ based on birth year, with individuals born after 1960 being more strongly affected. This suggests that the impact of genetics on obesity and cardiovascular risks may be amplified in the increasingly obesogenic environment.
CIRCULATION-GENOMIC AND PRECISION MEDICINE
(2023)
Article
Endocrinology & Metabolism
Tiange Liu, Fan Jia, Moira K. Differding, Ni Zhao, Myriam Doyon, Luigi Bouchard, Patrice Perron, Renee Guerin, Eric Masse, Marie-France Hivert, Noel T. Mueller
Summary: Maternal pre-pregnancy body mass index (BMI) is associated with the diversity and composition of gut microbiota in mothers and children 5 years after birth. However, the nature and direction of these associations differ between mothers and children, suggesting the need for further research.
INTERNATIONAL JOURNAL OF OBESITY
(2023)
Article
Biochemistry & Molecular Biology
Jordi Merino, Hassan S. Dashti, Douglas E. Levy, Magdalena Del Rocio Sevilla-Gonzalez, Marie-France Hivert, Bianca C. Porneala, Richa Saxena, Anne N. Thorndike
Summary: This study investigates the impact of genetic variants on macronutrient preference and long-term food choices. The results show that an increase in the polygenic score for carbohydrate preference is associated with more monthly food purchases and a higher number of purchases with green-labeled food. However, there is no evidence of associations between fat and protein polygenic scores and food purchases.
MOLECULAR PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Sheryl L. Rifas-Shiman, Izzuddin M. Aris, Karen M. Switkowski, Jessica Young, Abby F. Fleisch, Tamarra James-Todd, Ami R. Zota, Wei Perng, Marie-France Hivert, Janet W. Rich-Edwards, Melissa Perez Capotosto, Jorge E. Chavarro, Emily Oken
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Endocrinology & Metabolism
Jia Zhu, Anders U. Eliasen, Izzuddin M. Aris, Sara E. Stinson, Jens-Christian Holm, Torben Hansen, Marie-France Hivert, Klaus Bonnelykke, Rany M. Salem, Joel N. Hirschhorn, Yee-Ming Chan
Summary: Genetic risk factors for PCOS are associated with alterations in metabolic, growth, and developmental traits in childhood.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Cardiac & Cardiovascular Systems
Mingyu Zhang, Izzuddin M. Aris, Pi-I Debby Lin, Sheryl L. Rifas-Shiman, Tammy M. Brady, Tamarra James-Todd, Emily Oken, Marie-France Hivert
Summary: This study found associations between prenatal and childhood PFAS exposures and blood pressure at specific time points, but no consistent associations across all time points or PFAS types.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)