Melanocortin-4 Receptor Gene Mutations in a Dutch Cohort of Obese Children

Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference

(2009) Florianne Bauer et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

In silico mutagenesis: a case study of the melanocortin 4 receptor

(2009) Yana Bromberg et al.   FASEB JOURNAL

CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated genes

(2008) Matthew S Hestand et al.   BMC BIOINFORMATICS

Prevalence of Melanocortin-4 Receptor Deficiency in Europeans and Their Age-Dependent Penetrance in Multigenerational Pedigrees

(2008) F. Stutzmann et al.   DIABETES

Increased constraints on MC4R during primate and human evolution

(2008) David A. Hughes et al.   HUMAN GENETICS

The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women

(2008) L. Qi et al.   HUMAN MOLECULAR GENETICS

Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study

(2008) M. A. Calton et al.   HUMAN MOLECULAR GENETICS

Common variants near MC4R are associated with fat mass, weight and risk of obesity

(2008) Ruth J F Loos et al.   NATURE GENETICS