Article
Chemistry, Inorganic & Nuclear
Yi Li, Hao-Tian Wang, Yan-Long Zhao, Jie Lv, Xin Zhang, Qiang Chen, Jian-Rong Li
Summary: The hydrophobic property of metal-organic frameworks (MOFs) is crucial for stability and performance in various applications, which can be achieved through hydrophobic modification. This study systematically regulates water adsorption and hydrophobicity of the classical MOF MIL-101(Cr) through post-synthetic modification, allowing for tunable contact angles, water adsorption capacity, and step pressure.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Engineering, Environmental
Malcom Frimpong Dapaah, Baojian Liu, Liang Cheng
Summary: This study demonstrated the high adsorption capacity of MIL-101-N-2-pyc in removing organic pollutants like BPA, ANI, and FUR from aqueous solutions, showing promise for industrial applications. The adsorption mechanism mainly involved hydrogen bonding, π-π interaction, and electrostatic attraction, with the adsorbent exhibiting structural stability and low leaching of chromium into water. The adsorbent regeneration process was also efficient, making it a potentially valuable material for environmental remediation.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Nanoscience & Nanotechnology
Patrick Pires Conti, Paul Iacomi, Meilanie Nicolas, Guillaume Maurin, Sabine Devautour-Vinot
Summary: MIL-101(Cr) films were used as humidity sensors on quartz crystal microbalance and interdigitated electrode transductors. These devices exhibit high sensitivity, fast response/recovery times, good repeatability, long-term stability, favorable selectivity against toluene, and dual mode behavior in the optimal domain of humidity for indoor air.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Environmental Sciences
Derya Unlu
Summary: MIL-101(Cr) and MIL-101(Cr)@GO were added to PVA membranes to enhance their performance in pervaporative desalination. The effects of MIL-101(Cr) and MIL-101(Cr)@GO content, feed NaCl concentration, and operation temperature on flux and salt rejection were investigated. The hybrid membranes showed improved purification performance, with MIL-101(Cr)@GO doping achieving a salt rejection of 99.99% and a flux of 9.7 kg/m(2) h. They also maintained their separation performance over 10 cycles.
WATER AIR AND SOIL POLLUTION
(2023)
Article
Chemistry, Applied
Abdollah Ghiasi, Akbar Malekpour, Shokouh Mahpishanian
Summary: An aptamer-functionalized magnetic metal-organic framework was developed for selective magnetic solid phase extraction of acetamiprid. The method showed high recovery, low detection limit, good linearity, and stability, making it practically applicable for trace analysis of acetamiprid in various matrices.
Review
Biochemistry & Molecular Biology
Minmin Zou, Ming Dong, Tian Zhao
Summary: This review provides an overview of the latest synthesis methods of MIL-101(Cr) and its research progress in adsorption and catalysis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nanoscience & Nanotechnology
Paul Iacomi, Ezgi Gulcay, Patrick Pires Conti, Subharanjan Biswas, Nathalie Steunou, Guillaume Maurin, Guillaume Rioland, Sabine Devautour-Vinot
Summary: Volatile methylsiloxanes (VMSs) are common silicone degradation byproducts that cause serious concern. The mesoporous MIL-101(Cr) MOF is highlighted as a promising mass sensing layer for detecting VMS, and it shows excellent reversibility, repeatability, and fast response/recovery times.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Engineering, Environmental
Xinjia Zhang, Yaqi Wang, Jianguo Mi, Junsu Jin, Hong Meng
Summary: In this study, a dual modification approach was employed to improve the removal efficiency of volatile organic compounds (VOCs) using metal-organic framework (MOF) MIL-101(Cr) powder. The first modification involved crystallizing MIL-101(Cr) on the surface of amine grafting macroporous polyacrylate (PA-NH2) spheres, resulting in smaller crystal size. The second modification involved the synthesis of a hydrophobic composite P-MIL-101(Cr)@PA-NH2 using chemical vapor deposition (CVD) with polydimethylsiloxane (PDMS). The modified material exhibited excellent adsorption performance and structural stability, making it highly promising for VOC capture.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Nuttapong Makmeesub, Chonlada Ritvirulh, Kittisak Choojun, Suchinda Sattayaporn, Daniel E. Resasco, Tawan Sooknoi
Summary: In this study, highly stable Pd2+ species were successfully anchored on ethylenediamine-grafted MIL-101(Cr), which effectively prevented reduction and leaching of the catalyst, resulting in improved catalytic activity and stability.
CATALYSIS SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Jianwei Fu, Lin Wang, Yuheng Chen, Deyi Yan, Huase Ou
Summary: The grafting of a phenyl-ethyl side chain with low surface energy into metal-organic frameworks through a post-synthetic modification method increased hydrophobicity and water stability. The resulting MIL-101(Fe)-EPU showed high degradation efficiency and stability in photocatalysis reactions.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Applied
Yukun Lu, Changle Yue, Boxu Liu, Min Zhang, Yaping Li, Wenfeng Yang, Yan Lin, Yuan Pan, Daofeng Sun, Yunqi Liu
Summary: This study reported for the first time the preparation of a novel host-guest composite by anchoring Weakley-type polyoxometalate Na-7 [H2LaW10O36] in mesoporous metal-organic framework MIL-101(Cr) using a facile tandem post-synthetic modification strategy. The as-synthesized composite demonstrated obvious host-guest synergistic effect, excellent catalytic performance as a heterogeneous single-site catalyst for the ODS process, outstanding recyclability, and stability.
MICROPOROUS AND MESOPOROUS MATERIALS
(2021)
Article
Chemistry, Physical
Rui Zhao, Xueyan Bai, Wenhui Yang, Kun Fan, Haiyang Zhang
Summary: Chiral metal-organic frameworks (cMOFs) are promising chiral stationary phases for enantioseparation in high-performance liquid chromatography (HPLC). In this study, MIL-101-Ppa@SiO2 was synthesized by coordination post-synthetic modification using (S)-(+)-2-Phenylpropionic acid and applied as the chiral stationary phase. The results showed that MIL-101-Ppa@SiO2 exhibited higher chiral ligand density and better chiral separation performance compared to NH2-MIL-101-Ppa@SiO2.
Article
Chemistry, Applied
Oana Grad, Monica Dan, Lucian Barbu-Tudoran, Nicoleta Tosa, Mihaela D. Lazar, Gabriela Blanita
Summary: This study investigates the synthesis of hierarchical MOFs/gamma-Al2O3 composites under hydrothermal conditions by depositing MIL-53(Cr) or MIL-101(Cr) on the surface of porous alumina supports. The influence of different parameters on the nature and quality of the composites is systematically studied. The results show that successful synthesis conditions for MIL-53(Cr)/gamma-Al2O3 composites are 150 degrees C, 12 h, and a specific molar ratio.
MICROPOROUS AND MESOPOROUS MATERIALS
(2023)
Article
Engineering, Environmental
Faraz Ege, Darshan G. Pahinkar
Summary: A new wash-coating technique was developed to coat a porous layer of MIL-101 (Cr) adsorbent on fused silica microchannels. The optimized adsorbent slurry was prepared using ethanol solvent, silica binder, and MIL-101 (Cr) and inserted into the microchannels. The coatings were characterized using SEM and water adsorption isotherms.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Ghader Mahmodi, Rasoul Rahimzadeh Bafti, Negin Iranpour Boroujeni, Sushobhan Pradhan, Shailesh Dangwal, Bratin Sengupta, Vahid Vatanpour, Mirco Sorci, Mahdi Fathizadeh, Prem Bikkina, Georges Belfort, Miao Yu, Seok-Jhin Kim
Summary: By incorporating MIL-101(Cr)-NH2 nanoparticles into a cellulose acetate matrix, mixed matrix membranes with enhanced hydrophilicity were developed, effectively addressing fouling issues in industrial wastewater treatment. The prepared membranes exhibited high stability and rejection efficiency, with improved antifouling properties.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Zhenggao Xiao, Ningke Fan, Wenqing Zhu, Hai-Long Qian, Xiu-Ping Yan, Zhenyu Wang, Sergio Rasmann
Summary: The application of nanosilicon has been found to enhance plant defenses against various stresses. Silicon quantum nanodots, with their unique biological and physiochemical properties, show promise in regulating plant responses to stress. By studying maize, it was observed that the addition of Si NDs and sodium silicate effectively inhibited the growth of caterpillars and activated defense genes. Field experiments also demonstrated the potential of Si NDs in increasing maize yield. These findings suggest that Si NDs can be an effective and ecofriendly crop protection strategy in agroecosystems.
Article
Chemistry, Analytical
Shu-Ting Xu, Cheng Yang, Xiu-Ping Yan
Summary: Cell cycle discrimination is crucial for studying cellular heterogeneity in single-cell analysis based on organic mass spectrometry. A robust protocol using three small molecular indicators was developed to discriminate single cells at different cycle stages in real time. This protocol successfully discriminated single cells at G0/G1, S, and G2/M stages and revealed significant heterogeneity in amino acids, nucleotides, energy metabolic intermediates, and phospholipids among cells at different cycle stages.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Analytical
Shu-Ting Xu, Xiu-Ping Yan, Hai-Long Qian
ANALYTICAL CHEMISTRY
(2023)
Article
Materials Science, Composites
Dan Wang, Yidong Peng, Jiancheng Dong, Lei Pu, Kangqi Chang, Xiu-Ping Yan, Le Li, Yunpeng Huang, Tianxi Liu
Summary: In this study, polyimide aerogel fibers were fabricated using an in-situ polymerization method and wet-spinning technique with Ti3C2Tx flakes as pore-generating agents. These aerogel fibers showed enhanced mechanical properties, large specific surface area, excellent flame resistance, and remarkable thermal insulation performance. They can be woven into flexible textiles for practical thermal regulating applications.
COMPOSITES COMMUNICATIONS
(2023)
Article
Nanoscience & Nanotechnology
Li-Ya Wang, Li-Jian Chen, Xu Zhao, Yan Lv, Tianxi Liu, Xiu-Ping Yan
Summary: The researchers report an activatable antimicrobial nanoplatform with ultralow-background persistent luminescent (PL) turn-on imaging and therapeutic capability. The platform utilizes chitosan as a linker to immobilize copper ions on the surface of persistent luminescent nanoparticles (PLNPs) to fabricate PLNPs-CS-Cu2+. The PL emission of PLNPs is quenched by Cu2+ under physiological conditions but recovered due to the conversion of Cu2+ into Cu+ by high glutathione (GSH) levels at the infection site. The as-prepared antibacterial nanoplatform shows promise for highly sensitive persistent luminescent imaging and simultaneous treatment of bacterial infection.
ACS APPLIED NANO MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Jingxiao Chen, Yufeng Wang, Le Li, Yue-E Miao, Xu Zhao, Xiu-Ping Yan, Chao Zhang, Wei Feng, Tianxi Liu
Summary: In this study, an ultrastretchable fluorinated ionogel with high transparency and waterproofness is prepared. The ionogel exhibits stable cross-linking structures, high mechanical elasticity, and self-healing capabilities. It also demonstrates excellent stretchability, mechanical toughness, and underwater strain-sensing performances. This work provides a method for obtaining waterproof ionogel elastomers for next-generation underwater sensors and communications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Kangqi Chang, Zhenzhong Wu, Jian Meng, Minhao Guo, Xiu-Ping Yan, Hai-Long Qian, Piming Ma, Jianhua Zhao, Fangneng Wang, Yunpeng Huang, Tianxi Liu
Summary: Inspired by the nanotopography of cicada wings, a highly sensitive tactile sensor was fabricated by nanotexturing polyaniline nanoneedles on a conductive and elastic carbon skeleton. The sensor exhibited ultrahigh sensitivity, fast response/recovery abilities, and reproducible sensing performance, making it capable of distinguishing motions in a wide pressure range, detecting spatial pressure distribution, and monitoring various gestures in a wireless manner. These excellent performances demonstrate the great potential of nature-inspired tactile sensors for practical human motion monitoring and artificial intelligence applications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Applied
Jiang-Yue Wang, Li-Jian Chen, Xu Zhao, Xiu-Ping Yan
Summary: A pH-responsive colorimetric microneedle (MN) patch made from bromothymol blue (BTB) and silk fibroin meth acryloyl (SilMA) was developed for sensing salmon spoilage. The MN patch could extract tissue fluids from salmon and display color changes based on the pH variation caused by the increase of total volatile basic nitrogen. This method allows rapid determination of salmon spoilage and can be analyzed nondestructively on a smartphone.
Article
Biochemistry & Molecular Biology
Pengwu Xu, Gaopeng Qi, Dongxuan Lv, Deyu Niu, Weijun Yang, Huiyu Bai, Xiuping Yan, Xu Zhao, Piming Ma
Summary: In this study, an in situ polymerization method was employed to intercalate P-N-containing hyperbranched macromolecules (HBM) among BNT layers (HBM-B) to improve the flame retardancy and mechanical properties of PHA. The LOI of the PHA/HBM-B composite reached 27.6% when the mass ratio of HBM to BNT was 75/25. When the content of HBM-B reached 15 wt%, the LOI of PHA-Based composites reached 29.6% and achieved a UL-94 rating of V-0, meeting the standard of flame-retardant material.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Environmental
Shuyan Wu, Shichao Cai, Fengyang Qin, Feng He, Tianxi Liu, Xiuping Yan, Zhenyu Wang
Summary: Ball milling is effective in activating and reducing the size of microscale zero valent iron (mZVI) and sulfidating mZVI mechanochemically. However, there are differences in the interaction between chlorinated ethenes (CEs) and ball milled mZVI (mZVIbm) and mechanochemically sulfidated mZVI (S-mZVIbm) that are not well understood. This study found that simple ball milling exposed active Fe0 sites, while mechanochemical sulfidation decreased Fe0 sites and increased S2 sites. The sulfidation process enhanced the reactivity of TCE dechlorination the most, followed by PCE and 1,1-DCE, but reduced the reactivity of trans-DCE, cis-DCE, and VC compared to simple ball milling. Sulfidation also improved the electron efficiency of CE dechlorination, except for cis-DCE and VC. The kSA of cis-DCE, VC, and trans-DCE dechlorination positively correlated with the sulfide content.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Xu Zhao, Kang-Kang Zhang, Li-Jian Chen, Zhen-Yu Wang, Xiu-Ping Yan
Summary: We design and synthesize an acid-activated near-infrared probe to construct an intelligent theranostic nanoplatform for tumor-targeting image-guided photothermal and photodynamic therapy. The nanoplatform combines precise tumor targeting ability, specific imaging with a high signal-to-noise ratio, and excellent in vivo antitumor activity.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Li-Ya Wang, Li-Xia Yan, Xu Zhao, Li-Jian Chen, Xiu-Ping Yan
Summary: This study developed a pH-responsive theragnostic nanoplatform for targeted imaging and local drug release at the bacterial infection site. The nanoplatform consists of core-shell structure with persistent luminescence nanoparticles (PLNPs) as the core and zeolitic imidazolate framework-8 (ZIF-8) as the shell loaded with antibiotics. The nanoparticles were further conjugated with folic acid (FA) to achieve autofluorescence-free targeted imaging at the infection site. The acidic microenvironment at the bacterial infection site enables ZIF-8 to decompose and release drugs, improving the efficacy of bacterial infection treatment.
Article
Nanoscience & Nanotechnology
Xu Zhao, Ming-Yue Yin, Tian-Yue Gu, Xue-Mei Gao, Li-Jian Chen, Zhen-Yu Wang, Xiu-Ping Yan
Summary: This study reported a pH-/H2O2-activated and self-luminous nanosphere for intelligent bacteria-targeting and self-reported imaging-guided precision phototherapy sterilization. The nanosphere, formed by self-assembly of CMC-PC-N with CPPO, can rapidly release CPPO in the bacterial acidic microenvironment. The released CPPO can activate the fluorescence of the porphyrin for self-report imaging and achieve efficient phototherapy sterilization under external irradiation.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Analytical
Xue-Mei Gao, Tian-Yue Gu, Ke-Lin Chen, Xu Zhao, Xiu-Ping Yan
Summary: In this study, an intelligent luminescence ratiometric sensor based on ultra-small dual-emissive PLNP is reported for precise tumor-targeted imaging. The PLNP-Mal@Cy5.5 sensor can achieve long-term retention and specificity imaging by detecting the change of I-708/I-501.
ANALYSIS & SENSING
(2023)
Article
Nanoscience & Nanotechnology
Kangqi Chang, Zhenzhong Wu, Jian Meng, Minhao Guo, Xiu-Ping Yan, Hai-Long Qian, Piming Ma, Jianhua Zhao, Fangneng Wang, Yunpeng Huang, Tianxi Liu
Summary: We propose a simple strategy to fabricate a highly sensitive tactile sensor by nanotexturing erected polyaniline (PANI) nanoneedles on a conductive and elastic three-dimensional (3D) carbon skeleton. The developed sensor exhibits ultrahigh sensitivity, fast response/recovery abilities, and reproducible sensing performance, making it capable of distinguishing motions, detecting spatial pressure distribution, and monitoring various gestures wirelessly.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
