Environment, dysbiosis, immunity and sex-specific susceptibility: A translational hypothesis for regressive autism pathogenesis

Altered Metabolites in the Plasma of Autism Spectrum Disorder: A Capillary Electrophoresis Time-of-Flight Mass Spectroscopy Study

(2013) Hitoshi Kuwabara et al.   PLoS One

Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children

(2013) Dae-Wook Kang et al.   PLoS One

The Gut Microbiome: A New Frontier in Autism Research

(2013) Jennifer G. Mulle et al.   Current Psychiatry Reports

Sex-biased gene expression in the developing brain: implications for autism spectrum disorders

(2013) Mark N Ziats et al.   Molecular Autism

Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder

(2013) R E Frye et al.   Translational Psychiatry

Autism spectrum disorder in children born preterm—role of exposure to perinatal inflammation

(2013) Suzanne J. Meldrum et al.   Frontiers in Neuroscience

Autism spectrum disorder and celiac disease: no evidence for a link

(2012) Icaro Camargo Batista et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Molecular Characterisation of Gastrointestinal Microbiota of Children With Autism (With and Without Gastrointestinal Dysfunction) and Their Neurotypical Siblings

(2012) Shakuntla V. Gondalia et al.   Autism Research

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

The microbiome as a human organ

(2012) F. Baquero et al.   CLINICAL MICROBIOLOGY AND INFECTION

Does the Human Gut Microbiota Contribute to the Etiology of Autism Spectrum Disorders?

(2012) Petra Louis   DIGESTIVE DISEASES AND SCIENCES

Metabolic differences underlying two distinct rat urinary phenotypes, a suggested role for gut microbial metabolism of phenylalanine and a possible connection to autism

(2012) T. Andrew Clayton   FEBS LETTERS

Hypothesis: Bacteria Control Host Appetites

(2012) V. Norris et al.   JOURNAL OF BACTERIOLOGY

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

(2012) G Clarke et al.   MOLECULAR PSYCHIATRY

Neurodevelopment: Unlocking the brain

(2012) Jon Bardin   NATURE

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Cytokine dysregulation in autism spectrum disorders (ASD): Possible role of the environment

(2012) Paula E. Goines et al.   NEUROTOXICOLOGY AND TERATOLOGY

Effectiveness of the gluten-free, casein-free diet for children diagnosed with autism spectrum disorder: Based on parental report

(2012) Christine M. Pennesi et al.   NUTRITIONAL NEUROSCIENCE

Autism After Infection, Febrile Episodes, and Antibiotic Use During Pregnancy: An Exploratory Study

(2012) H. O. Atladottir et al.   PEDIATRICS

Gut microbiota, immune development and function

(2012) Stig Bengmark   PHARMACOLOGICAL RESEARCH

Npas4: A Neuronal Transcription Factor with a Key Role in Social and Cognitive Functions Relevant to Developmental Disorders

(2012) Laurence Coutellier et al.   PLoS One

State of the art; microbiology in health and disease. Intestinal bacterial flora in autism

(2011) Sydney M. Finegold   ANAEROBE

Microbiology of regressive autism

(2011) Sydney M. Finegold et al.   ANAEROBE

Biosynthesis and function of gliotoxin in Aspergillus fumigatus

(2011) Daniel H. Scharf et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Gender Specific Differences in the Immune Response to Infection

(2011) Erin E. McClelland et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Autism spectrum disorders are associated with an elevated autoantibody response to tissue transglutaminase-2

(2011) Allen Rosenspire et al.   Autism Research

Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

(2011) James B Adams et al.   BMC GASTROENTEROLOGY

Milk from cows of different β-casein genotypes as a source of β-casomorphin-7

(2011) Anna Cieślińska et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Mechanisms of Mycotoxin-Induced Neurotoxicity through Oxidative Stress-Associated Pathways

(2011) Kunio Doi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nucleus Accumbens  -Opioid Receptors Mediate Social Reward

(2011) V. Trezza et al.   JOURNAL OF NEUROSCIENCE

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Necrotizing Enterocolitis

(2011) Josef Neu et al.   NEW ENGLAND JOURNAL OF MEDICINE

The level of arabinitol in autistic children after probiotic therapy

(2011) Joanna Kałużna-Czaplińska et al.   NUTRITION

Sensory Processing in Autism: A Review of Neurophysiologic Findings

(2011) ELYSA J. MARCO et al.   PEDIATRIC RESEARCH

Probiotics and health: An evidence-based review

(2011) Paolo Aureli et al.   PHARMACOLOGICAL RESEARCH

Sex Hormones in Autism: Androgens and Estrogens Differentially and Reciprocally Regulate RORA, a Novel Candidate Gene for Autism

(2011) Tewarit Sarachana et al.   PLoS One

A Study of Nuclear Transcription Factor-Kappa B in Childhood Autism

(2011) Usha S. Naik et al.   PLoS One

Characterization of the Diversity and Temporal Stability of Bacterial Communities in Human Milk

(2011) Katherine M. Hunt et al.   PLoS One

Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances

(2011) Brent L. Williams et al.   PLoS One

Expression Profiling of Autism Candidate Genes during Human Brain Development Implicates Central Immune Signaling Pathways

(2011) Mark N. Ziats et al.   PLoS One

Aberrant NF-KappaB Expression in Autism Spectrum Condition: A Mechanism for Neuroinflammation

(2011) Adam M. H. Young et al.   Frontiers in Psychiatry

Transglutaminase participates in the blockade of neurotransmitter release by tetanus toxin: evidence for a novel biological function

(2010) Francesco Facchiano et al.   AMINO ACIDS

Pyrosequencing study of fecal microflora of autistic and control children

(2010) Sydney M. Finegold et al.   ANAEROBE

Effects of the enteric bacterial metabolic product propionic acid on object-directed behavior, social behavior, cognition, and neuroinflammation in adolescent rats: Relevance to autism spectrum disorder

(2010) Derrick F. MacFabe et al.   BEHAVIOURAL BRAIN RESEARCH

Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome

(2010) Paul Ashwood et al.   BRAIN BEHAVIOR AND IMMUNITY

Gene and miRNA expression profiles in autism spectrum disorders

(2010) Mohammad M. Ghahramani Seno et al.   BRAIN RESEARCH

Alterations of the Intestinal Barrier in Patients With Autism Spectrum Disorders and in Their First-degree Relatives

(2010) Laura de Magistris et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Urinary Metabolic Phenotyping Differentiates Children with Autism from Their Unaffected Siblings and Age-Matched Controls

(2010) Ivan K. S. Yap et al.   JOURNAL OF PROTEOME RESEARCH

Transannular Disulfide Formation in Gliotoxin Biosynthesis and Its Role in Self-Resistance of the Human PathogenAspergillus fumigatus

(2010) Daniel H. Scharf et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From Structure to Function: the Ecology of Host-Associated Microbial Communities

(2010) C. J. Robinson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

Genome-wide expression studies in Autism spectrum disorder, Rett syndrome, and Down syndrome

(2010) Carla Lintas et al.   NEUROBIOLOGY OF DISEASE

The food-associated fungal neurotoxin ochratoxin A inhibits the absorption of glutamate by astrocytes through a decrease in cell surface expression of the excitatory amino-acid transporters GLAST and GLT-1

(2010) Helisoa Razafimanjato et al.   NEUROTOXICOLOGY

Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite ofClostridiaspp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia

(2010) William Shaw   NUTRITIONAL NEUROSCIENCE

Recommendations for Evaluation and Treatment of Common Gastrointestinal Problems in Children With ASDs

(2010) Timothy Buie et al.   PEDIATRICS

Succession of microbial consortia in the developing infant gut microbiome

(2010) J. E. Koenig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biosynthesis and Toxicological Effects of Patulin

(2010) Olivier Puel et al.   Toxins

Deoxynivalenol-Induced Proinflammatory Gene Expression: Mechanisms and Pathological Sequelae

(2010) James J. Pestka   Toxins

Establishment of the gut microbiota in Western infants

(2009) I Adlerberth et al.   ACTA PAEDIATRICA

Crucial Role of Acetaldehyde in Alcohol Activation of the Mesolimbic Dopamine System

(2009) Marco Diana et al.   Annals of the New York Academy of Sciences

Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome

(2009) B. Chakrabarti et al.   Autism Research

The plasma zinc/serum copper ratio as a biomarker in children with autism spectrum disorders

(2009) Scott Faber et al.   BIOMARKERS

Increase in Cerebellar Neurotrophin-3 and Oxidative Stress Markers in Autism

(2009) Elizabeth M. Sajdel-Sulkowska et al.   CEREBELLUM

Gender-dependent differences in the incidence of ochratoxin A-induced neural tube defects in thePdn/Pdnmouse

(2009) Etsuko Ueta et al.   CONGENITAL ANOMALIES

Gender Differences in P-Glycoprotein Expression and Function: Effects on Drug Disposition and Outcome

(2009) M. Bebawy et al.   CURRENT DRUG METABOLISM

The Relationship Between Intestinal Microbiota and the Central Nervous System in Normal Gastrointestinal Function and Disease

(2009) Stephen M. Collins et al.   GASTROENTEROLOGY

Candida albicans Releases Soluble Factors That Potentiate Cytokine Production by Human Cells through a Protease-Activated Receptor 1- and 2-Independent Pathway

(2009) S.-C. Cheng et al.   INFECTION AND IMMUNITY

SOX E genes: SOX9 and SOX8 in mammalian testis development

(2009) Francisco Barrionuevo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Celiac Disease Presenting as Autism

(2009) Stephen J. Genuis et al.   JOURNAL OF CHILD NEUROLOGY

Elevated immune response in the brain of autistic patients

(2009) Xiaohong Li et al.   JOURNAL OF NEUROIMMUNOLOGY

Autism

(2009) Susan E Levy et al.   LANCET

The blood–brain barrier and immune function and dysfunction

(2009) William A. Banks et al.   NEUROBIOLOGY OF DISEASE

Immune Proteins in Brain Development and Synaptic Plasticity

(2009) Lisa M. Boulanger   NEURON

Epidemiology of Pervasive Developmental Disorders

(2009) Eric Fombonne   PEDIATRIC RESEARCH

β-Casomorphins-7 in infants on different type of feeding and different levels of psychomotor development

(2009) Natalya V. Kost et al.   PEPTIDES

Functional Characterization of the Antibiotic Resistance Reservoir in the Human Microflora

(2009) M. O. A. Sommer et al.   SCIENCE

Ochratoxin A–Mediated DNA and Protein Damage: Roles of Nitrosative and Oxidative Stresses

(2009) Christophe Cavin et al.   TOXICOLOGICAL SCIENCES

Vision in autism spectrum disorders

(2009) David R. Simmons et al.   VISION RESEARCH

Human gut microbiota and bifidobacteria: from composition to functionality

(2008) Francesca Turroni et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Absence of urinary opioid peptides in children with autism

(2008) H Cass et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Sexually dimorphic activation of the periaqueductal gray–rostral ventromedial medullary circuit during the development of tolerance to morphine in the rat

(2008) Dayna R. Loyd et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Mechanisms of deoxynivalenol-induced gene expression and apoptosis

(2008) J.J. Pestka   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Neonatal protection by an innate immune system of human milk consisting of oligosaccharides and glycans1

(2008) D. S. Newburg   JOURNAL OF ANIMAL SCIENCE

Androgen and estrogen (α) receptor localization on periaqueductal gray neurons projecting to the rostral ventromedial medulla in the male and female rat

(2008) Dayna R. Loyd et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Sex Differences in  -Opioid Receptor Expression in the Rat Midbrain Periaqueductal Gray Are Essential for Eliciting Sex Differences in Morphine Analgesia

(2008) D. R. Loyd et al.   JOURNAL OF NEUROSCIENCE

Effects of Feedborne Fusarium Mycotoxins on Brain Regional Neurochemistry of Turkeys

(2008) C. K. Girish et al.   POULTRY SCIENCE

The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing

(2008) Les Dethlefsen et al.   PLOS BIOLOGY

Detoxification of patulin and ochratoxin A, two abundant mycotoxins, by lactic acid bacteria

(2007) S. Fuchs et al.   FOOD AND CHEMICAL TOXICOLOGY

Therapy and epidemiology of autism–clostridial spores as key elements

(2007) Sydney M. Finegold   MEDICAL HYPOTHESES