Hypoxic stress, brain vascular system, and β-amyloid: A primary cell culture study

Alzheimer's Disease, Cerebrovascular Disease, and the β-amyloid Cascade

(2014) Kie Honjo et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Cerebral amyloidal angiopathy—A disease with implications for neurology and psychiatry

(2013) Maximilian Gahr et al.   BRAIN RESEARCH

The regulation of AβPP expression by RNA-binding proteins

(2012) Cara J. Westmark et al.   AGEING RESEARCH REVIEWS

Alzheimer's therapeutics: Continued clinical failures question the validity of the amyloid hypothesis—but what lies beyond?

(2012) Kevin Mullane et al.   BIOCHEMICAL PHARMACOLOGY

Alpha-Secretase Cleavage of the Amyloid Precursor Protein: Proteolysis Regulated by Signaling Pathways and Protein Trafficking

(2012) Stefan F. Lichtenthaler   Current Alzheimer Research

Cerebral amyloid angiopathy impact on endothelium

(2012) Lea Tenenholz Grinberg et al.   EXPERIMENTAL GERONTOLOGY

Activation of NMDA Receptors Upregulates A Disintegrin and Metalloproteinase 10 via a Wnt/MAPK Signaling Pathway

(2012) X.-Z. Wan et al.   JOURNAL OF NEUROSCIENCE

BACE1 levels are elevated in congestive heart failure

(2012) Hikmet F. Nural-Guvener et al.   NEUROSCIENCE LETTERS

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

(2011) Mario Merlini et al.   ACTA NEUROPATHOLOGICA

Ginsenoside Rg1 promotes nonamyloidgenic cleavage of APP via estrogen receptor signaling to MAPK/ERK and PI3K/Akt

(2011) Chun Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Neurovascular function in Alzheimer's disease patients and experimental models

(2011) Nektaria Nicolakakis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer’s Disease

(2011) Xiulian Sun et al.   JOURNAL OF NEUROCHEMISTRY

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

The role of G protein-coupled receptors in the pathology of Alzheimer's disease

(2011) Amantha Thathiah et al.   NATURE REVIEWS NEUROSCIENCE

p53, a Pivotal Effector of a Functional Cross-Talk Linking Presenilins and Pen-2

(2011) F. Checler et al.   Neurodegenerative Diseases

Oxidative Stress and Hypoxia Contribute to Alzheimer's Disease Pathogenesis: Two Sides of the Same Coin

(2011) Michela Guglielmotto et al.   TheScientificWorldJOURNAL

APP processing in Alzheimer's disease

(2011) Yun-wu Zhang et al.   Molecular Brain

Regulation of alpha-secretase ADAM10 expression and activity

(2011) Kristina Endres et al.   EXPERIMENTAL BRAIN RESEARCH

The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia

(2010) Costantino Iadecola   ACTA NEUROPATHOLOGICA

Effect of VEGF and its receptor antagonist SU-5416, an inhibitor of angiogenesis, on processing of the β-amyloid precursor protein in primary neuronal cells derived from brain tissue of Tg2576 mice

(2010) Susanne Bürger et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

IGF-1 Reduces BACE-1 Expression in PC12 Cells via Activation of PI3-K/Akt and MAPK/ERK1/2 Signaling Pathways

(2010) Hua Zhang et al.   NEUROCHEMICAL RESEARCH

The Vascular Hypothesis of Alzheimer’s Disease: Bench to Bedside and Beyond

(2010) Jack C. de la Torre   Neurodegenerative Diseases

Vascular basis for brain degeneration: faltering controls and risk factors for dementia

(2010) Raj N Kalaria   NUTRITION REVIEWS

Microvasculature changes and cerebral amyloid angiopathy in Alzheimer’s disease and their potential impact on therapy

(2009) Roy O. Weller et al.   ACTA NEUROPATHOLOGICA

Presenilin-dependent regulated intramembrane proteolysis and γ-secretase activity

(2009) J. V. McCarthy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pathological role of hypoxia in Alzheimer's disease

(2009) Xin Zhang et al.   EXPERIMENTAL NEUROLOGY

Vascular endothelial growth factor (VEGF) affects processing of amyloid precursor protein and β-amyloidogenesis in brain slice cultures derived from transgenic Tg2576 mouse brain

(2009) Susanne Bürger et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Possible involvement of NO/NOS signaling in hippocampal amyloid-β production induced by transient focal cerebral ischemia in aged rats

(2009) Song Li et al.   NEUROSCIENCE LETTERS

β-Amyloid, Blood Vessels, and Brain Function

(2009) Eric E. Smith et al.   STROKE

Linking vascular disorders and Alzheimer's disease: Potential involvement of BACE1

(2008) Sarah L. Cole et al.   NEUROBIOLOGY OF AGING

JNK and ERK1/2 pathways have a dual opposite effect on the expression of BACE1

(2008) Elena Tamagno et al.   NEUROBIOLOGY OF AGING

Oxidative stress triggers the amyloidogenic pathway in human vascular smooth muscle cells

(2007) Mireia Coma et al.   NEUROBIOLOGY OF AGING

Hypoxia increases Aβ generation by altering β- and γ-cleavage of APP

(2007) Liang Li et al.   NEUROBIOLOGY OF AGING