Article
Chemistry, Multidisciplinary
Paula M. Castillo, Francisco J. Fernandez-Acejo, Jose M. Carnerero, Rafael Prado-Gotor, Aila Jimenez-Ruiz
Summary: The study utilizes the stabilizing effect of lysozymes to develop a quick naked-eye test for detecting urinary lysozyme concentrations over 57.2 μg/mL. By calculating color difference parameters, the test can reliably provide a positive colorimetric response in less than 15 minutes, making it useful for detecting disorders such as leukemia-associated lysozymurias.
Article
Chemistry, Inorganic & Nuclear
Sadhana Kundu, Pradip Kar
Summary: In this study, stable aqueous colloid of 4-quinonimine (4-QI) functionalized gold nanoparticles (AuNPs) was used for selective colorimetric sensing of fluoride ion in water. The intensity of the surface Plasmon absorption band at 535 nm decreased significantly in the UV-visible spectra of AuNPs with increasing concentration of fluoride ion. The sensitivity of the 4-QI functionalized AuNPs for fluoride ion was obtained as approximately 340 μM-1 with a detection limit of 0.17 μM, while the sensitivity for chloride ion was only about 64 μM-1 with a detection limit of 0.93 μM.
JOURNAL OF CLUSTER SCIENCE
(2023)
Article
Chemistry, Analytical
Jing-Lin He, Ling Tang, Shi-Qing Liao, Mei-Tong Guo, Ling Wu, Yinghui Song, Sulai Liu, Zhong Cao
Summary: A label-free platform utilizing target-triggered hybridization and inhibition of gold nanoparticle aggregation was developed for naked-eye detection of telomerase activity. This method offers a cost-effective approach for cancer diagnosis and identification of breast cancer phenotypes.
Article
Materials Science, Multidisciplinary
V. Ramkumar, P. Kamachiyappan, R. Manjunath, S. Balamurugan, A. Ashokkumar, M. K. Ashraf Ali, S. C. Kim
Summary: A highly selective and sensitive receptor for Al3+ and Cu2+ ions was synthesized and characterized. The receptor exhibited solvatochromism and keto-enol tautomerism properties in different solvents. It was found to be a highly selective colorimetric sensor for Al3+ ions, and a turn-off sensor for Cu2+ ions. The highlight of this work is its effectiveness as a naked-eye sensor for both Al3+ and Cu2+ ions.
Article
Chemistry, Analytical
Ritika Gupta, Amit Kumar, Sandeep Kumar, Anil Kumar Pinnaka, Nitin Kumar Singhal
Summary: This study developed a detection platform utilizing the properties of gold nanoparticles and graphene oxide to detect E. coli cells through aptamer conjugation. The sensitivity of the designed nanoprobe was enhanced by covering AuNPs with graphene oxide. This platform was found to be applicable in glass capillary for making a point of care detection device.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Qiaoyin Li, Haiyan Chen, Shumin You, Zhenyu Lin, Zhitao Chen, Fengping Huang, Bin Qiu
Summary: Proper amount of fluorion is important for human health, but excessive fluorion is harmful. A colorimetric and fluorescence enhanced sensor, using MOF material UiO-66 combined with fluorescent dye FITC, is proposed to detect fluorion with high selectivity. It has a good linear relationship in the range of 2-150 mu M (0.038-2.85 ppm), and has been applied to the detection of actual water samples. Field visual detection of fluoride ion is realized, expanding the application of MOF in fluorescence sensing.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Physical
Liu Yang, Yu-Long Liu, Cheng-Guo Liu, Ying Fu, Fei Ye
Summary: HNA is a dual-platform colorimetric and ratiometric chemosensor designed to detect fluoride anion in DMSO solution. It shows excellent selectivity and sensitivity, with color changes from yellow to purple when F- is present. The detection limit is as low as 0.61 mu M, and it has a binding model with F- in a 3:2 stoichiometry ratio. HNA has the potential to be a superior chemosensor for monitoring F- selectively and sensitively.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
Arezoo Saadati, Fatemeh Farshchi, Mohammad Hasanzadeh, Yuqian Liu, Farzad Seidi
Summary: In this study, a fast and sensitive colorimetric method was developed to accurately detect trace amounts of arsenic. By changing the morphology of silver nanoparticles, the color of the nanoparticles changed, which was visible to the naked eye. The proposed probes showed good performance in the experiments and could be used to detect arsenic levels in human urine samples.
Article
Spectroscopy
Neha Singh, Sonu Kumari, Suphiya Khan
Summary: A low-cost and highly sensitive colorimetric detector for fluoride ions using carbon quantum dots and metal salts was developed, showing high selectivity towards fluoride ions compared to other ions. The detector exhibited a linear response in the range of 2-8 ppm, with color changes observable to the naked eye at concentrations as low as 2 ppm. Fluoride ion detection was successfully conducted in water samples from different districts, highlighting the wide sensing range of the developed colorimetric detector.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Almas Shamaila Mohammed, Aniket Balapure, Mahammad Nanne Khaja, Ramakrishnan Ganesan, Jayati Ray Dutta
Summary: The increasing incidence of HCV infection is a major concern worldwide. A rapid and cost-effective detection assay using an Au NP based strategy has been developed for early and sensitive detection of HCV RNA, which can be beneficial for mass screening even in resource-limited settings.
Article
Chemistry, Inorganic & Nuclear
Marimuthu Ponram, Bharathkumar Thangaraj, Suresh Ranganathan, Baskaran Sambath, Ravichandran Cingaram, Sathiyanarayanan Kulathu Iyer, Karthikeyan Natesan Sundaramurthy
Summary: A new chemosensor TPA-SB with high selectivity and sensitivity for Hg2+ was designed and synthesized. A paper sensor coated with TPA-SB was developed for rapid detection of Hg2+ with excellent selectivity and sensitivity. TPA-SB-SiO2 was also developed as an adsorbent for complete removal of Hg2+ ions from contaminated water. Additionally, the sensing system demonstrated the ability to recognize Hg2+ ions in Escherichia coli cells.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Somayeh Tarasi, Ali Ramazani, Ali Morsali, Mao-Lin Hu
Summary: A sacrificial metal-organic framework (MOF) was developed for naked-eye detection and measurement of Hg2+ in various solutions. It is capable of both qualitative and quantitative sensing, with a turn-off fluorescence sensor for detecting low concentrations of Hg2+.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Analytical
Maria Lopez-Valls, Carmen Escalona-Noguero, Ciro Rodriguez-Diaz, Demian Pardo, Milagros Castellanos, Paula Milan-Rois, Carlos Martinez-Garay, Rocio Coloma, Melanie Abreu, Rafael Canton, Juan Carlos Galan, Rodolfo Miranda, Alvaro Somoza, Begona Sot
Summary: The COVID-19 pandemic highlights the necessity of fast and sensitive detection methods to prevent pathogen spread. In this study, the authors present CASCADE, a sensing system that allows rapid naked-eye detection of SARS-CoV-2 RNA. CASCADE utilizes LwaCas13a CRISPR protein and gold nanoparticles to recognize and visualize target RNA.
ANALYTICA CHIMICA ACTA
(2022)
Review
Chemistry, Analytical
Jianyu Yang, Xin Wang, Yuyang Sun, Bo Chen, Fangxin Hu, Chunxian Guo, Ting Yang
Summary: Infectious pathogens pose a significant threat to public health due to their high infectivity and lethal capacity. Gold nanoparticles have gained attention in colorimetric biosensing for their unique physicochemical properties. Colorimetric diagnosis platforms based on functionalized AuNPs are promising for pathogen detection due to their high sensitivity, low-cost, and ease of use. This review summarizes recent developments in this field, including different colorimetric strategies and biomolecule-functionalized AuNP-based sensors, and offers future research directions and challenges.
Article
Chemistry, Analytical
Mengxin Mu, Xin Ke, Wenyu Cheng, Jie Li, Chendong Ji, Meizhen Yin
Summary: A colorimetric and fluorescent probe based on perylenemonoimide was designed and synthesized for the detection of aqueous fluoride ions. The probe showed high sensitivity, good selectivity, and reversibility. It could quantitatively detect fluorocarbons with a low detection limit and enable rapid and naked-eye detection of fluoride ions in drinking water.
ANALYTICAL CHEMISTRY
(2022)
Review
Instruments & Instrumentation
Ivan Diarra, Krishna Kumar Kotra, Surendra Prasad
Summary: This review critically examines the current practices in phytoremediation and its prospects for the treatment of HM-contaminated sites in PICTs. It also reviews the limitations of traditional spectroscopic techniques such as inductively coupled plasma mass spectroscopy/atomic emission spectroscopy (ICP-MS/AES) and the promise of novel techniques such as field portable X-ray fluorescence spectrometry (FP-XRF), atmospheric pressure discharge plasma (APDP) and lab on chip (LOC) in phytoremediation studies.
APPLIED SPECTROSCOPY REVIEWS
(2022)
Article
Dermatology
Rajna Ogrin, Mohammod A. Motin, Behzad Aliahmad, Kylie Elder, Jacinta Anderson, Dinesh Kumar
Summary: This study investigated the effectiveness of using thermal imaging to predict venous leg ulcer healing in the homes of participants. The results showed that thermal imaging could not predict the healing progression of ulcers when taken in home settings.
INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
(2023)
Article
Multidisciplinary Sciences
Sheik Mohammed Ali, Sridhar Poosapadi Arjunan, James Peters, Laura Perju-Dumbrava, Catherine Ding, Michael Eller, Sanjay Raghav, Peter Kempster, Mohammod Abdul Motin, P. J. Radcliffe, Dinesh Kant Kumar
Summary: This study proposes the use of wearable accelerometer sensors for the quantitative assessment of essential tremor (ET). The results show that the sensor located on the forearm had the best classification and regression results, with moderate to good correlation between Fahn-Tolosa-Marin (FTM) scores and a combination of power spectral density ratio and task time. However, the system could not accurately differentiate ET phenotypes according to the Consensus classification scheme.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Inorganic & Nuclear
Ritu Painuli, Sapna Raghav, Prakash C. Jha, Mohd Athar, Dinesh Kumar
Summary: In this study, we developed a fast and selective detection method for Hg(II) ions in aqueous solutions using caffeic acid decorated silver nanoparticles. The method involves using a paper strip as a dipstick type device, which can detect Hg(II) ions in a concentration range of 20-0.0001 ppm with naked eyes.
INORGANIC AND NANO-METAL CHEMISTRY
(2023)
Article
Management
Amit Kumar Yadav, Dinesh Kumar
Summary: This paper proposes a lean-agile-green practices approach to improve the efficiency of the vaccine supply chain. A fuzzy decision framework is used to prioritize practices and it is found that sustainable packaging, coordination among supply chain stakeholders, and cold chain technology improvement have the greatest impact on performance indicators. The findings of this study will help policymakers in reframing strategies for a sustainable vaccine supply chain.
INTERNATIONAL JOURNAL OF PRODUCTIVITY AND PERFORMANCE MANAGEMENT
(2023)
Article
Plant Sciences
Kiran Sharma, Rachna Verma, Dinesh Kumar, Eugenie Nepovimova, Kamil Kuca, Ashwani Kumar, Disha Raghuvanshi, Rajni Dhalaria, Sunil Puri
Summary: This study focuses on the usage of different ethnomedicinal plants in the treatment of neurodegenerative diseases in different regions of Himachal Pradesh, India. The study reveals 73 ethnomedicinal plants used for various neurological disorders, with a particular emphasis on plants used for epilepsy. The study also highlights the importance of phytochemicals and their neuroprotective effects in traditional medicine.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Multidisciplinary Sciences
Dinesh Kumar, Frederic Ayant, Kottakkaran Sooppy Nisar, Daya Lal Suthar
Summary: In this article, we introduce the concepts of fractional-order Kober and generalized Weyl q-integrals, as well as present the properties and results of Riemann-Liouville and Weyl fractional q-integral transforms. By specializing variables and parameters, a wide variety of useful basic functions can be obtained.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES
(2023)
Article
Chemistry, Applied
Wilson Maeaba, Surendra Prasad
Summary: The study analyzed the macroelement content of calcium, magnesium, potassium, and sodium in tropical fruits from Solomon Islands using flame atomic absorption spectrometer. The results showed varying concentrations of these elements in different fruits, with breadfruit having the highest potassium content and cutnut having the highest calcium and magnesium content. Banana had the highest sodium concentration. The recommended dietary allowance (RDA) coverage for macroelements in these fruits was highest for children, followed by adolescents and adults.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Engineering, Environmental
Niharika Singh, Ankita Dhillon, Dinesh Kumar
Summary: Access to safe drinking water is crucial, as its scarcity and inadequacy can have catastrophic effects on humanity. The use of metal-organic frameworks (MOFs) has emerged as a promising solution in alleviating water fluoridation. Their exceptional properties, such as high adsorption capacity and adjustability, make them stand out from other conventional methods. Understanding the influencing factors and optimal conditions for MOFs in defluoridation can provide necessary information for enhancing their functioning in the field.
GROUNDWATER FOR SUSTAINABLE DEVELOPMENT
(2023)
Review
Chemistry, Applied
Poonam Singh, Surendra Prasad
Summary: Micronutrients such as iron, zinc, and calcium are needed in small amounts by the human body and play a significant role in human health. Deficiencies in these micronutrients can have life-threatening consequences, with iron deficiency and anemia being the most prevalent. This review focuses on the dietary sources of iron, zinc, and calcium, their importance in biological processes, and their effects on various diseases. It also examines the bioavailability of these micronutrients and the factors that influence their bioavailability, including phytates, tannins, oxalates, ascorbic acid, food processing techniques, and interactions among minerals. The review also discusses food processing methods that can reduce phytate levels and enhance the bioavailability of these minerals.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Analytical
Naresh A. Rajpurohit, Kaushalya Bhakar, Meena Nemiwal, Tian C. Zhang, Dinesh Kumar
Summary: In this study, an electrochemical sensor modified with CeW@rGO nanocomposites was designed and prepared for the detection of the toxic substance hydroquinone. The CeW-6@rGO nanocomposite showed optimal electrochemical behavior and exhibited long-term stability with high selectivity. The sensor demonstrated reliable detection of hydroquinone in real-world water samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Shadhon Chandra Mohonta, Mohammod Abdul Motin, Dinesh Kant Kumar
Summary: In this study, a deep-learning approach is proposed to detect arrhythmia from short segments of ECG. The scalogram obtained by continuous wavelet transform is classified by a convolutional neural network, achieving high sensitivity, specificity, and accuracy.
SENSING AND BIO-SENSING RESEARCH
(2022)
Article
Mathematics
Norbert Suedland, Joerg Volkmann, Dinesh Kumar
Summary: Algebraic equations of degree 4 have been solved analytically since Cardano, but the discovery of two algorithms with the same solutions brings a new insight into the solution methods.
ANNALES UNIVERSITATIS PAEDAGOGICAE CRACOVIENSIS-STUDIA MATHEMATICA
(2022)
Article
Engineering, Multidisciplinary
Sunil S. Kumar, Neelakantha Londe, Dilip K. Kumar, M. Kittur, Irfan Anjum Badruddin, Mohammed Faheem, Sher Afghan Khan
Summary: Accelerated salt spray corrosion tests were conducted on Al6061T6 and Al7075T6 aluminum alloys, showing that the oxide layer lost its protective properties after prolonged exposure, leading to further corrosion. The increase in exposure time significantly decreased the tensile properties, impact strength, and hardness. Al7075T6 was found to be more susceptible to corrosion compared to Al6061T6.
INTERNATIONAL JOURNAL OF INTEGRATED ENGINEERING
(2022)
Article
Mathematics, Interdisciplinary Applications
Dinesh Kumar, Dumitru Baleanu, Frederic Ayant, Norbert Suedland
Summary: In this work, we derived the fractional order q-integrals and q-derivatives for a basic analogue of the Aleph-function with two variables (AFTV). We discussed its related application and the q-extension of the corresponding Leibniz rule. Additionally, we presented two corollaries involving the basic analogue of the I-function with two variables and the basic analogue of the Aleph-function with one variable.
FRACTAL AND FRACTIONAL
(2022)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
